hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj00259/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0537  ( 575 res)   mfj00259

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    264.8    6.7e-75   1
TyrKc    Tyrosine kinase, catalytic domain               27.3    7.9e-13   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TyrKc      1/1       1   222 [.     1   280 []    27.3  7.9e-13
S_TKc      1/1       1   224 [.     1   231 []   264.8  6.7e-75

Alignments of top-scoring domains:
TyrKc: domain 1 of 1, from 1 to 222: score 27.3, E = 7.9e-13
                   *->ltlgkkLGeGaFGeVykGtlkieVAVKtLkeda......keeFlrEa
                                               +K++++d+ +++ ++  ++rE+
   mKIAA0537     1    -------------------------IKSIRKDKikdeldMVHIRREI 22   

                   kiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldyLr
                   +iM++l  +Hp+i+ ++ v   +       + + i+mEy+++G L dy+ 
   mKIAA0537    23 EIMSSL--NHPHIISIYEVFENK-------DKIVIIMEYASKGELYDYIS 63   

                   knrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenkvvKI
                   ++r+ ls ++  +f  QI +   Y +++++vHRDL   N+L+++n  +KI
   mKIAA0537    64 ERRR-LSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKI 112  

                   sDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEslkdgkF.
                   +DFGLs     d      k   +     +g    P+   +PE  + + ++
   mKIAA0537   113 ADFGLSNLYQKD------KFLQTF----CG---SPL-YASPEIVNGRPYr 148  

                   tskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGyRlpkP
                    ++ D W+ GVlL+  + +G +P  g      + + +++++ +G+++++ 
   mKIAA0537   149 GPEVDSWALGVLLY-TLIYGTMPFDG-----FDHKNLIRQISSGEYREPT 192  

                   endlpiSsvtCPdelYd.lMlqCWaedPedRPtFselverl<-*
                   +               ++l+++  + +P+ R t +++   +   
   mKIAA0537   193 QP-----------SDARgLIRWMLMVNPDRRATIEDIANHW    222  

S_TKc: domain 1 of 1, from 1 to 224: score 264.8, E = 6.7e-75
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik.....erilrEiki
                                      + + k+        +ik++ +  +i+rEi+i
   mKIAA0537     1    ---------------IKSIRKD--------KIKdeldmVHIRREIEI 24   

                   Lkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgrrglrk
                   +++ +HP+I+ +y+vfe++dk+ ++mEy++   G+L+d++ +r+r     
   mKIAA0537    25 MSSlNHPHIISIYEVFENkDKIVIIMEYASK--GELYDYISERRR----- 67   

                   vlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvKlaDFG
                    lsE+e+r++frQi+sa+ Y+H++g++HRDLK eNiLLd++ ++K+aDFG
   mKIAA0537    68 -LSErETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDncNIKIADFG 116  

                   lArql......ttfvGTpeYmAPEvl...gYgkpavDiWSlGcilyEllt
                   l+ ++++++   tf+G+p Y +PE++++++Y +p+vD W+lG++ly l++
   mKIAA0537   117 LSNLYqkdkflQTFCGSPLYASPEIVngrPYRGPEVDSWALGVLLYTLIY 166  

                   GkpPFp..qldlifkkig.........SpeakdLikklLvkdPekRlta.
                   G  PF++ +++ ++++i ++++++++ +++a+ Li+ +L ++P++R t++
   mKIAA0537   167 GTMPFDgfDHKNLIRQISsgeyreptqPSDARGLIRWMLMVNPDRRATIe 216  

                   eaLedeldikaHPff<-*
                   ++ +       H ++   
   mKIAA0537   217 DIAN-------HWWV    224  

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