hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj00259/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0537  ( 575 res)   mfj00259

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       274.7    1.2e-78   1
Pkinase_Tyr Protein tyrosine kinase                      44.4    1.2e-14   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase_Tyr   1/1       1   222 [.     1   272 []    44.4  1.2e-14
Pkinase       1/1       1   224 [.     1   287 []   274.7  1.2e-78

Alignments of top-scoring domains:
Pkinase_Tyr: domain 1 of 1, from 1 to 222: score 44.4, E = 1.2e-14
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtLkeigasseeie
                      +k ++k              +             ++k+   +  +  
   mKIAA0537     1    IKSIRK--------------D-------------KIKD-ELDMVH-- 17   

                   redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL
                        rE++iM++l +Hp+i++ + v    ++     + i++Ey+ +G L
   mKIAA0537    18 ---IRREIEIMSSL-NHPHIISIYEVFEN-KDK----IVIIMEYASKGEL 58   

                   ldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLVs
                   +d+  +   +r+L+  +  +f +Qi ++  Y + +++vHRDL   N+L++
   mKIAA0537    59 YDYISE---RRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLD 105  

                   enlvVKIsDFGLaRdiynddyYvrkkgggklPvkWmAPEslkygkF.tsk
                   +n  +KI+DFGL+ + ++d    ++  g++l     +PE  + + ++  +
   mKIAA0537   106 DNCNIKIADFGLSNLYQKDKFL-QTFCGSPL---YASPEIVNGRPYrGPE 151  

                   SDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPenCPde
                    D W+ GVlL+ ++  G +P + g +   ++ ++  +G+  ++ +  P +
   mKIAA0537   152 VDSWALGVLLYTLIY-GTMP-FDGFDHKNLIRQI-SSGEYREPTQ--PSD 196  

                   lYdlMlqCWaedPedRPtFselverL<-*
                      l++   + +P++R t +++ ++    
   mKIAA0537   197 ARGLIRWMLMVNPDRRATIEDIANHW    222  

Pkinase: domain 1 of 1, from 1 to 224: score 274.7, E = 1.2e-78
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                                                  +K i+k+k+k++ d+ ++r
   mKIAA0537     1    ----------------------------IKSIRKDKIKDELDMVHIR 19   

                   rsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrlldLfdylse
                   r Ei+i+ +L+Hp+I+ +++vfe+kd++ +++Ey+ +G    +L+dy+s 
   mKIAA0537    20 R-EIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKG----ELYDYIS- 63   

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldengv
                     ++++l  se+e +++++Qi++++ Y+H+ng++HRDLK+eNILld+n +
   mKIAA0537    64 --ERRRL--SERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCN 109  

                   vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD
                   +    KiaDFGl+ +  ++++  l+tf+G+p Y++PE+++g+++ g++vD
   mKIAA0537   110 I----KIADFGLSNL--YqKDKfLQTFCGSPLYASPEIVNGRPYRGPEVD 153  

                   vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi
                    W+lGv+ly l+ G  PF+g      d++ lir+i +++++++ +     
   mKIAA0537   154 SWALGVLLYTLIYGTMPFDGF-----DHKNLIRQISSGEYREPTQ----- 193  

                   srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                              +++a+ Li+++L ++P +R t+e+i +H w+   
   mKIAA0537   194 -----------PSDARGLIRWMLMVNPDRRATIEDIANHWWV    224  

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