hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg05983/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA0531  ( 987 res)   mbg05983

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N 
--------      -----------                               -----    ------- ---
Kinesin       Kinesin motor domain                      576.6   1.6e-169   1
Spindle_assoc Spindle associated                         -3.9       0.92   1
Filament      Intermediate filament protein            -185.9       0.44   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
Kinesin         1/1      45   359 ..     1   424 []   576.6 1.6e-169
Spindle_assoc   1/1     861   914 ..     1    63 []    -3.9     0.92
Filament        1/1     715   946 ..     1   359 []  -185.9     0.44

Alignments of top-scoring domains:
Kinesin: domain 1 of 1, from 45 to 359: score 576.6, E = 1.6e-169
                   *->RvRPlnerEksrgs.vvvnvsedvessrltn.gkkktFtFDkVFdpe
                      R+RPlne E+ rg++++    ++ ++  +   g+ k + FD+V +p+
   mKIAA0531    45    RFRPLNEAEILRGDkFI----PKFKGEETVViGQGKPYVFDRVLPPN 87   

                   atQegssepYAsqefvyesvakPlvesvleGyNgtiFAYGQTGSGKTYTM
                   +t          qe+vy+ +ak++v++vleGyNgtiFAYGQT SGKT+TM
   mKIAA0531    88 TT----------QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTM 127  

                   eGppesdkesgnptddsytlpeeepGiiPRaledlFerieerkerkpvfK
                   eG+                 +++ +GiiPR+ +d+F++i           
   mKIAA0531   128 EGKLH---------------DPQLMGIIPRIAHDIFDHI----------- 151  

                   Pklnekgwellnsqetligvsfdrglssdly.v.ndlefsvkvSylEIYN
                                                 y+++++lef++kvSy+EIY 
   mKIAA0531   152 ------------------------------YsMdENLEFHIKVSYFEIYL 171  

                   EkirDLLspsppqrgspskanekkkkkpLrireDpkrGgkmdgvyVeGLt
                    kirDLL+ s             k++  L ++eD++r      +yV+G+t
   mKIAA0531   172 DKIRDLLDVS-------------KTN--LAVHEDKNRV-----PYVKGCT 201  

                   eveVssaeevlelLelGnknRtvasTkmNerSSRSHaiFtitveqrntds
                   e  Vss+eev+ ++++G +nR+va T+mNe+SSRSH+iF i ++q+n ++
   mKIAA0531   202 ERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVET 251  

                   tgsvvtgkdnsgeesvrvskLnLVDLAGSERaskTgatgAggrRLkEaan
                   +                ++kL+LVDLAGSE++skTg   A+g  L Ea+n
   mKIAA0531   252 EKK-------------LSGKLYLVDLAGSEKVSKTG---AEGAVLDEAKN 285  

                   INkSLsaLGnVInALadkqkssHiPYRDSKLTrLLqDSLGGGDNsKTlMI
                   INkSLsaLGnVI+ALa++  ++H+PYRDSK Tr+LqDSLGG  N++T+++
   mKIAA0531   286 INKSLSALGNVISALAEG-TKTHVPYRDSKMTRILQDSLGG--NCRTTIV 332  

                   aniSPsssrNntnyeETLsTLrFAsRAKnIk<-*
                    ++SPs      n  ET sTL F++RAK Ik   
   mKIAA0531   333 ICCSPSVF----NEAETKSTLMFGQRAKTIK    359  

Spindle_assoc: domain 1 of 1, from 861 to 914: score -3.9, E = 0.92
                   *->LkKENFgLKLkIyFLeErLnkkseegiediiKeNiELKvevesLqRd
                              K kI FLe  L ++     +     N +L  e+ +L + 
   mKIAA0531   861    --------KQKISFLENNLEQLT-KVHKQLVRDNADLRCELPKLEKR 898  

                   lqgykkklsklekqle<-*
                   l    ++++ le++l+   
   mKIAA0531   899 LRATAERVKALESALK    914  

Filament: domain 1 of 1, from 715 to 946: score -185.9, E = 0.44
                   *->nEKeqmQnLNDRLAsYIdKVRfLEqqNkeLevkieelrqkqsrggpa
                      +EKe +  L D            E+ +k+Le + e +r+ +++    
   mKIAA0531   715    KEKEHLTRLQD-----------AEEVKKALEQQMESHREAHQK---- 746  

                   svsrlyslYeteieeLRrqidqltnerarlqlEidnlrealedfrkKyed
                    +srl++    eiee +r id+    + +lqlE + l  ++ +++ + ++
   mKIAA0531   747 QLSRLRD----EIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQE 792  

                   Ke.DLaaQnqlkdlEialntkeaeLaTaL..eRqeaEndlvgLRaQiAkl
                    e +L         E  l         +L++ R+ a +dl+gL       
   mKIAA0531   793 REvKL---------EKLL---------LLndKREQAREDLKGL------- 817  

                   EslaaRkdlDeaTLarvDLEnkvEsLqEElaFLKknHeEEvkeLqaqiqd
                             e+T +r     ++++L      L+k++   v +L  ++  
   mKIAA0531   818 ----------EETVSR-----ELQTLHN----LRKLF---VQDLTTRVKK 845  

                   tgqvnVEmDaarqqEwklDLtkaLrEiRaQYEeiAeknrqeaEewYksKl
                   +  v ++ D++                       A++         k+K+
   mKIAA0531   846 S--VELDSDDGG--------------------GSAAQ---------KQKI 864  

                   eeLqtaaarngealrsaKeEitElRRqiQsLeiELqslksqnasLErqla
                   + L    ++ +   ++    + +lR  +  Le +L +     ++LE +l 
   mKIAA0531   865 SFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALK 914  

                   ElEeryeaelaqyqalisqlEeeLqqlreEMarqLrEYQeLLdVKlaLDi
                   E++e   ++++ yq    +  e+++     Mar                 
   mKIAA0531   915 EAKENAMRDRKRYQQEVDRIKEAVRA--KNMAR----------------- 945  

                   EIATYRKLLEGEEsR<-*
                                 R   
   mKIAA0531   946 --------------R    946  

//