hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs Sequence file: /cdna4/rodent/full/goal/mic/mic36088/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA0524 ( 729 res) mic36088 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- SAM Sterile alpha motif. 100.8 1.6e-25 2 TIR Toll - interleukin 1 - resistance 81.3 1.2e-19 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- SAM 1/2 419 481 .. 1 67 [] 53.3 3.1e-11 SAM 2/2 484 553 .. 1 67 [] 47.7 1.5e-09 TIR 1/1 566 707 .. 1 147 [] 81.3 1.2e-19 Alignments of top-scoring domains: SAM: domain 1 of 2, from 419 to 481: score 53.3, E = 3.1e-11 *->vs.wspesVaeWLesigleqYadnFrkngidgeelllltseedLkel v +w++ +V+ WL+ ig++qY++nFr ++ll+lt+ee+ ++l mKIAA0524 419 VAsWKEAEVQTWLQQIGFSQYCENFRG-----DLLLRLTDEELQTDL 460 GitllGhRkkIlsaiqklkeq<-* G+++ Rk++++++ +lk++ mKIAA0524 461 GMKSSITRKRFFRELTELKTF 481 SAM: domain 2 of 2, from 484 to 553: score 47.7, E = 1.5e-09 *->vs.wspesVaeWLesigleq..YadnFrkngidgeelllltseedLk + +++ +++a+WL s++ ++Y++ + ++g+d ++l++ +++++L+ mKIAA0524 484 YAtCDRSNLADWLGSLDPRFrqYTYGLVSCGLDRSLLHRVSEQQLLE 530 elGitllGhRkkIlsaiqklkeq<-* ++Gi l hR +Ilsa ++++++ mKIAA0524 531 DCGIRLGVHRTRILSAAREMLHS 553 TIR: domain 1 of 1, from 566 to 707: score 81.3, E = 1.2e-19 *->eydvFiSfrgdeedvrnefvshLlkalrgkgklcvFiDdfepgggda ++dvFiS+r+ + + +++ + ++ +l+g+ vFiD++ +++g++ mKIAA0524 566 TPDVFISYRR-NSGSQLASLLKVHLQLHGF---SVFIDVEKLEAGKF 608 enkllpelfeaIekSriaivvlSpnYaeSeWCld.lElvaalecale..g e+k l++++ ++r +++vlS ++ +++++++ + ++e ++ ++ mKIAA0524 609 EDK----LIQSVIAARNFVLVLSAGALDKCMQDHdCKDWVHKEIVTAlsC 654 glrvIPIfyevi.sdvrkqtgkfgkvfkkngpedtylkwted....fWkk g++++PI+ + + ++ +++++++v+++n +kw+++ ++ +k mKIAA0524 655 GKNIVPIIDGFEwPEPQALPEDMQAVLTFN-----GIKWSHEyqeaTIEK 699 alysvpnk<-* ++++ + mKIAA0524 700 IIRFLQGR 707 //