hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg16592/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0520  ( 1334 res)   mbg16592

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N 
--------      -----------                               -----    ------- ---
Guanylate_cyc Adenylate and Guanylate cyclase catalyt   528.4     5e-155   2

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
Guanylate_cyc   1/2     366   554 ..     1   223 []   326.1  4.2e-94
Guanylate_cyc   2/2    1030  1225 ..     1   223 []   206.0  5.8e-58

Alignments of top-scoring domains:
Guanylate_cyc: domain 1 of 2, from 366 to 554: score 326.1, E = 4.2e-94
                   *->vyaqrydnVtilFaDIvGFTalssrhsvNngpeevvrlLNdlytrFD
                      +++q+ ++V+ilFaDIvGFT++s+++s    ++++v lLNdl++rFD
   mKIAA0520   366    FKMQQIEEVSILFADIVGFTKMSANKS----AHALVGLLNDLFGRFD 408  

                   eLldehkfgvyKvKTIGDaYMvasGlppaadqtkLakklqldsaaHaakl
                   +L++++  +++K+ T+GD+Y++++G+p++             +a+Ha+++
   mKIAA0520   409 RLCEQT--KCEKISTLGDCYYCVAGCPEP-------------RADHAYCC 443  

                   adfALdmveaiqevnvehanrepPtvLyrGlrvRiGiHtGpVvaGviGlt
                   ++++L+m++ai+++++e+++  +       +++R+G+HtG+V++G++G  
   mKIAA0520   444 IEMGLGMIKAIEQFCQEKKE--M-------VNMRVGVHTGTVLCGILG-- 482  

                   akrprYdvwGdTVNlASRmEStGvpgsekIhvseetyrlLkeeesfefef
                   ++r+++dvw+++VNlA++mE++Gv+g  k+h+se+t+++L +++++e+++
   mKIAA0520   483 MRRFKFDVWSNDVNLANLMEQLGVAG--KVHISEATAKYLDDRYEMEDGR 530  

                   aleprgeveVkGkgkpGeietYfLkg<-*
                   ++e++g++ V ++ k+  ++tY+++g   
   mKIAA0520   531 VIERLGQSVVADQLKG--LKTYLISG    554  

Guanylate_cyc: domain 2 of 2, from 1030 to 1225: score 206.0, E = 5.8e-58
                   *->vyaqrydnVtilFaDIvGFTalssrhsvNngpeevvrlLNdlytrFD
                       y++ +d+ +++Fa+Iv+F +++++    +g+ e+ r+LN+l+++FD
   mKIAA0520  1030    TYSKNHDSGGVIFASIVNFSEFYEENY--EGGKECYRVLNELIGDFD 1074 

                   eLldehkf.gvyKvKTIGDaYMvasGlppaadqtkLakklqlds..aaHa
                   eLl+++ ++ ++K+KTIG +YM+asGl  a        ++q+ +++  H+
   mKIAA0520  1075 ELLSKPDYnSIEKIKTIGATYMAASGLNTA--------QCQEGGhpQEHL 1116 

                   akladfALdmveaiqevnvehanrepPtvLyrGlrvRiGiHtGpVvaGvi
                   + l +fA +m+  ++ +n+  +   +       +++R+G ++Gp  aGvi
   mKIAA0520  1117 RILFEFAKEMMRVVDDFNNNMLW-FN-------FKLRVGFNHGPLTAGVI 1158 

                   GltakrprYdvwGdTVNlASRmEStGvpgsekIhvseetyrlLkeeesfe
                   G  + +  Yd+wGdTVN+ASRm++tGv    +I+vsee yr+L++ + ++
   mKIAA0520  1159 G--TTKLLYDIWGDTVNIASRMDTTGVEC--RIQVSEESYRVLSKMG-YD 1203 

                   fefaleprgeveVkGkgkpGeietYfLkg<-*
                   f++    rg v+VkGkg+   ++tY+ +    
   mKIAA0520  1204 FDY----RGTVNVKGKGQ---MKTYLYPK    1225 

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