hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj13077/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0517  ( 787 res)   mfj13077

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
NHL      NHL repeat                                     216.7    3.5e-61   6
zf-B_box B-box zinc finger                               55.2    1.4e-12   1
Filamin  Filamin/ABP280 repeat                           54.8    1.8e-12   1
zf-C3HC4 Zinc finger, C3HC4 type (RING finger)           39.9    5.6e-08   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
zf-C3HC4   1/1      66   106 ..     1    50 []    39.9  5.6e-08
zf-B_box   1/1     158   197 ..     1    46 []    55.2  1.4e-12
Filamin    1/1     365   461 ..     1   101 []    54.8  1.8e-12
NHL        1/6     529   556 ..     1    29 []    34.0  3.3e-06
NHL        2/6     576   603 ..     1    29 []    37.9  2.3e-07
NHL        3/6     618   645 ..     1    29 []    29.3  8.9e-05
NHL        4/6     665   692 ..     1    29 []    39.3  8.7e-08
NHL        5/6     712   739 ..     1    29 []    49.6    7e-11
NHL        6/6     756   783 ..     1    29 []    41.5  1.8e-08

Alignments of top-scoring domains:
zf-C3HC4: domain 1 of 1, from 66 to 106: score 39.9, E = 5.6e-08
                   *->CrICleelkepsndfplilpCgHsGslkyfCrsClerwlss.sgntt
                      C ICle +k+p+     +lpC+H+     fC+ Cl++++  +s + +
   mKIAA0517    66    CSICLERYKNPK-----VLPCLHT-----FCERCLQNYIPAhSLTLS 102  

                   CplC<-*
                   Cp+C   
   mKIAA0517   103 CPVC    106  

zf-B_box: domain 1 of 1, from 158 to 197: score 55.2, E = 1.4e-12
                   *->ervCpeHg.ekaslfCedDqalLCvvCdesgeHsanklargHtvvpl
                      +  Cp+H++ +++++C+ +++++C++C+e  eH      + H +vpl
   mKIAA0517   158    PLSCPNHDgNVMEFYCQSCETAMCRECTEG-EH------AEHPTVPL 197  

                   <-*
                      
   mKIAA0517     -     -    

Filamin: domain 1 of 1, from 365 to 461: score 54.8, E = 1.8e-12
                   *->agDasKVkAyGPGLeggGVkvgkPaeFtVdtVdkdGepkgAGgGgLs
                      ++ as   A G GL  +    g+P + t+ t dkdGe+++ G++ L+
   mKIAA0517   365    NAVASETVATGEGLRQT--IIGQPMSVTITTKDKDGELCKTGNAYLT 409  

                   VkVeGPsGaeAvvevkvtDngDGtYtVsYtPtepGdYtvnVtygGehIPg
                   +  + P+G   v + ++ Dn++GtY   Yt +++Gd t +  + ++hI g
   mKIAA0517   410 AELSTPDGS--VADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRG 457  

                   SPFk<-*
                   SPFk   
   mKIAA0517   458 SPFK    461  

NHL: domain 1 of 6, from 529 to 556: score 34.0, E = 3.3e-06
                   *->lnrPhGvavdpsdGrvyVaDsenhrvqvf<-*
                      + + +Gva + ++G +++aDs+n +vq+f   
   mKIAA0517   529    FTNLQGVAAS-TSGKILIADSNNQCVQIF    556  

NHL: domain 2 of 6, from 576 to 603: score 37.9, E = 2.3e-07
                   *->lnrPhGvavdpsdGrvyVaDsenhrvqvf<-*
                      l+rP+Gvav  ++G++++aD++n  v +f   
   mKIAA0517   576    LQRPTGVAVH-PSGDIIIADYDNKWVSIF    603  

NHL: domain 3 of 6, from 618 to 645: score 29.3, E = 8.9e-05
                   *->lnrPhGvavdpsdGrvyVaDsenhrvqvf<-*
                      l  P Gv vd ++G+++V+D+   +v++f   
   mKIAA0517   618    LMGPKGVSVD-RNGHIIVVDNKACCVFIF    645  

NHL: domain 4 of 6, from 665 to 692: score 39.3, E = 8.7e-08
                   *->lnrPhGvavdpsdGrvyVaDsenhrvqvf<-*
                      +  Ph  av+ s+++++++D++nh v+vf   
   mKIAA0517   665    FAGPHFAAVN-SNNEIIITDFHNHSVKVF    692  

NHL: domain 5 of 6, from 712 to 739: score 49.6, E = 7e-11
                   *->lnrPhGvavdpsdGrvyVaDsenhrvqvf<-*
                      +n P+Gvavd s+G+++VaD +n+r+qvf   
   mKIAA0517   712    FNAPTGVAVD-SNGNIIVADWGNSRIQVF    739  

NHL: domain 6 of 6, from 756 to 783: score 41.5, E = 1.8e-08
                   *->lnrPhGvavdpsdGrvyVaDsenhrvqvf<-*
                      l+ P+G+a++ sdG+v+VaDs+nh+ +v+   
   mKIAA0517   756    LYGPQGLALT-SDGHVVVADSGNHCFKVY    783  

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