hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh01581/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0472  ( 658 res)   mbh01581

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    137.4    1.5e-36   1
TyrKc    Tyrosine kinase, catalytic domain               67.5    1.7e-15   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
S_TKc      1/1     381   635 ..     1   231 []   137.4  1.5e-36
TyrKc      1/1     381   635 ..     1   280 []    67.5  1.7e-15

Alignments of top-scoring domains:
S_TKc: domain 1 of 1, from 381 to 635: score 137.4, E = 1.5e-36
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik.......erilrEi
                       +l+++lG+G +G+Vyl+ + + +  +A+K + ++++++ +++  E 
   mKIAA0472   381    PKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVppdekhwNDLALEF 427  

                   kiLkk..dHPNIVkLydvfed........dklylVmEyceGdlGdLfdll
                     +++ ++H+ +V L+++  d + +++++  + l+mE +     dL++ l
   mKIAA0472   428 HYMRSlpKHERLVDLHGSVIDynygggssVAVLLIMERLHR---DLYTGL 474  

                   kkrgrrglrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds
                   k          l+ ++   ++  +++++ +LHsqg +HRD+K  N+LLd+
   mKIAA0472   475 KAG--------LTLeTRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDK 516  

                   ..hvKlaDFGlArql....ttfvGTpeYmAPEvl..gYgkpavDiWSlGc
                   +++ K++D G+++     + ++vGTp  mAPE+++++Y+  +vD++++G+
   mKIAA0472   517 qnRAKITDLGFCKPEammsGSIVGTPIHMAPELFtgKYDN-SVDVYAFGI 565  

                   ilyElltGkpPFp.......qldlifkkig...........SpeakdLik
                   +++  ++G    p+  ++    d +++++++++++++ +  ++e+++L++
   mKIAA0472   566 LFWYICSGSIKLPeafercaSKDHLWNNVRrgtrperlpvfDEECWQLME 615  

                   klLvkdPekRltaeaLedeldikaHPff<-*
                    +++ dP kR+   + +        P +   
   mKIAA0472   616 ACWDGDPLKRPLLGIVQ--------PML    635  

TyrKc: domain 1 of 1, from 381 to 635: score 67.5, E = 1.7e-15
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda...keeFlrEa
                       +lg++LG+G++G+Vy++   +++ ++A K++ +  +++  ++  E 
   mKIAA0472   381    PKLGQELGRGQYGVVYLCDNWgghFPCALKSVVPPDekhWNDLALEF 427  

                   kiMkklGgkHpNiVkLlGvcte....egrrFmevePlmivmEymegGdLl
                     M++l +kH+ +V L+G +++ + ++       +    v+  me    +
   mKIAA0472   428 HYMRSL-PKHERLVDLHGSVIDynygG-------GSSVAVLLIMERLHRD 469  

                   dyLrknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenk
                    y   + + l+l++ l++Al++ +G ++L+s+++vHRD+   N+L+++++
   mKIAA0472   470 LYTGLKAG-LTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQN 518  

                   vvKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEslkd
                   ++KI+D G ++           +  ++      g    Pi  mAPE + +
   mKIAA0472   519 RAKITDLGFCKPEAMM------SGSIV------GT---PIH-MAPELF-T 551  

                   gkFtskSDVWSFGVlLWEiftlGeqPYpgeiqq.fmsneevleylkkGyR
                   gk+    DV++FG+l W i++   + ++   +++  s +++ +++++G R
   mKIAA0472   552 GKYDNSVDVYAFGILFWYICSGSIKLPEA--FErCASKDHLWNNVRRGTR 599  

                   lpkPendlpiSsvtCPdelYdlMlqCWaedPedRPtFselverl<-*
                   +++ +           +e  +lM+ CW+ dP +RP    +   l   
   mKIAA0472   600 PERLPV--------FDEECWQLMEACWDGDPLKRPLLGIVQPML    635  

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