hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh01581/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0472  ( 658 res)   mbh01581

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       141.0    2.2e-38   1
Pkinase_Tyr Protein tyrosine kinase                      76.6    5.1e-19   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase_Tyr   1/1     382   635 ..     1   272 []    76.6  5.1e-19
Pkinase       1/1     381   638 ..     1   287 []   141.0  2.2e-38

Alignments of top-scoring domains:
Pkinase_Tyr: domain 1 of 1, from 382 to 635: score 76.6, E = 5.1e-19
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtLkeigasseeie
                       klg++LG+G++G+Vy++       g++ ++A K++  +  ++++  
   mKIAA0472   382    -KLGQELGRGQYGVVYLCDNW----GGHFPCALKSV--VPPDEKH-- 419  

                   redFlrEAsiMkklGdHpNiVrLlGvctkegePg..gpg.lyiVtEymeg
                   + d+  E   M++l++H+ +V L+G +++    g++++  +++++E  + 
   mKIAA0472   420 WNDLALEFHYMRSLPKHERLVDLHGSVID-YNYGggSSVaVLLIMERLHR 468  

                   GdLldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNc
                    dL++ L++      Ltl++ l++al++ +G  +L+s+++vHRD+  +N+
   mKIAA0472   469 -DLYTGLKAG-----LTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNV 512  

                   LVsenlvVKIsDFGLaRdiynddyYvrkkgggk..lPvkWmAPEslkygk
                   L+++++ +KI+D G ++          + +g+  + P+  mAPE l++gk
   mKIAA0472   513 LLDKQNRAKITDLGFCKPE-------AMMSGSIvgTPIH-MAPE-LFTGK 553  

                   FtskSDVWSFGVlLWEiftlGe..qP..FYpgm.sneevlellyedGyRL
                   +    DV++FG+l W i++ G  + P+ F + + s   + + + ++G R 
   mKIAA0472   554 YDNSVDVYAFGILFWYICS-GSikLPeaF-ERCaSKDHLWNNV-RRGTRP 600  

                   prPenCPdelYdlMlqCWaedPedRPtFselverL<-*
                   +r +   +e  +lM  CW+ dP +RP    ++  L   
   mKIAA0472   601 ERLPVFDEECWQLMEACWDGDPLKRPLLGIVQPML    635  

Pkinase: domain 1 of 1, from 381 to 638: score 141.0, E = 2.2e-38
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                       +l++ lG+G +G+Vy++ + g     A+K +  ++ek++ d ++  
   mKIAA0472   381    PKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLAL-- 425  

                   rsEiqilkrL.sHpNIvrlidvfed.......kdhlylVlEycegGLrll
                     E +++++L++H+  v l++++ d + +++++  + l++E + +     
   mKIAA0472   426 --EFHYMRSLpKHERLVDLHGSVIDynygggsSVAVLLIMERL-HR---- 468  

                   dLfdylsetrrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeN
                   dL++ l+      +l  + ++   ial +++g+ +LHs+g +HRD+K+ N
   mKIAA0472   469 DLYTGLK-----AGL--TLETRLQIALDVVEGIRFLHSQGLVHRDIKLKN 511  

                   ILldengvvdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllgg
                   +Lld+++      Ki+D G++     +      ++vGTp  mAPE+  + 
   mKIAA0472   512 VLLDKQNRA----KITDLGFC----KpEAMmSGSIVGTPIHMAPEL--FT 551  

                   ngygtkvDvWSlGvilyelltGk....pPFsgevqds.ldqlqlirkilg
                    +y+ +vDv+++G+++++ ++G  + +  F  +    + d+l+  ++ + 
   mKIAA0472   552 GKYDNSVDVYAFGILFWYICSGSiklpEAFERC---AsKDHLWNNVRRGT 598  

                   pplefdspewdsisrsefrrlpnlseeakdLikkcLnkDPskRlt...ae
                   +p + + +                +ee+ +L++ c++ DP kR+  +  +
   mKIAA0472   599 RPERLPVF----------------DEECWQLMEACWDGDPLKRPLlgiVQ 632  

                   eilqHPwf<-*
                     l +  +   
   mKIAA0472   633 PMLRS--I    638  

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