hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg07539/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0463  ( 1529 res)   mbg07539

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
TIG      IPT/TIG domain                                 258.5    8.9e-74   4
PSI      Plexin repeat                                  153.4      4e-42   3

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PSI        1/3     145   195 ..     1    63 []    67.6  2.6e-16
PSI        2/3     290   337 ..     1    63 []    47.9  2.3e-10
PSI        3/3     438   491 ..     1    63 []    55.3  1.3e-12
TIG        1/4     493   587 ..     1   105 []    69.1  9.6e-17
TIG        2/4     589   673 ..     1   105 []    92.7  7.5e-24
TIG        3/4     676   775 ..     1   105 []    70.2  4.4e-17
TIG        4/4     778   871 ..     1   105 []    46.8  4.7e-10

Alignments of top-scoring domains:
PSI: domain 1 of 3, from 145 to 195: score 67.6, E = 2.6e-16
                   *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfyGeCprae.
                      +C+qyt+C++CL++ dp +CgWC++++ C+r++        C+ra++
   mKIAA0463   145    SCEQYTTCGECLSSGDP-HCGWCALHNMCSRRD-------KCQRAWe 183  

                   pendqwldwswssskCp<-*
                   ++     +++ s s+C    
   mKIAA0463   184 AN-----RFAASISQCM    195  

PSI: domain 2 of 3, from 290 to 337: score 47.9, E = 2.3e-10
                   *->nCsqytsCssCLaardpfyCgWCssegrCtrgsaytsfyGeCpraep
                      nCs+++ C sC+++    +C+WC++++ Ct+ ++       C+ +e 
   mKIAA0463   290    NCSAHQLCLSCVNSAF--RCHWCKYRNLCTHDPT------TCSFQE- 327  

                   endqwldwswssskCp<-*
                         +++++s++Cp   
   mKIAA0463   328 ------GRINVSEDCP    337  

PSI: domain 3 of 3, from 438 to 491: score 55.3, E = 1.3e-12
                   *->nCsqy.tsCssCLaardpfyCgWCssegrCtrgsaytsfyGeCprae
                      +C++++ sC+ CL a+ +f+CgWCs+e+rCt+++       +Cp+ +
   mKIAA0463   438    KCAAQrESCGLCLKADHKFECGWCSGERRCTLHQ-------HCPSTS 477  

                   pendqwldwswssskCp<-*
                      ++wldws+++ kC    
   mKIAA0463   478 ---SPWLDWSSHNVKCS    491  

TIG: domain 1 of 4, from 493 to 587: score 69.1, E = 9.6e-17
                   *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt
                      P It+i   sgp +GGt++Ti+G nlg          +f++  ++V 
   mKIAA0463   493    PQITEILTVSGPPEGGTRVTIHGVNLG---------LDFSEIAHHVQ 530  

                   fggtpvpCdvisssss..tqivCktPpva.ggpsppvvtvsvdgggsgdg
                   ++g+p  C++i+ +++  +qivC+ + +  g +s+p v++ ++ +  + +
   mKIAA0463   531 VAGVP--CTPIPGEYIiaEQIVCEMGHAViGTTSGP-VRLCIGECK-PEF 576  

                   rssspvtFtYv<-*
                   ++ s +++t+v   
   mKIAA0463   577 MTKSHQQYTFV    587  

TIG: domain 2 of 4, from 589 to 673: score 92.7, E = 7.5e-24
                   *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt
                      P++ s+sP +gp sGGt++TitG +lg+gs            ++ V+
   mKIAA0463   589    PSVLSLSPIRGPESGGTMVTITGHYLGAGS------------SVAVY 623  

                   fggtpvpCdvissssstqivCktPpva.ggpsppvvtvsvdgggsgdgrs
                   +g+++  C++  +s+ ++ivC++Pp+++g  + p v vsvd+++     +
   mKIAA0463   624 LGNQT--CEFYGRSM-NEIVCVSPPSSnGLGPVP-VSVSVDRAR-----V 664  

                   sspvtFtYv<-*
                    s+ +F+Y+   
   mKIAA0463   665 DSSLQFEYI    673  

TIG: domain 3 of 4, from 676 to 775: score 70.2, E = 4.4e-17
                   *->PvItsisPssgplsGGteiTitGsnlgsgsePrirkntfededikVt
                      P++++i+P+++ +sG t +TitG nl+ ++ePr+r          V+
   mKIAA0463   676    PRVQRIEPEWSITSGHTPLTITGFNLDVIQEPRVR----------VK 712  

                   fggtpv..pCdvissssstqivCktPpva.ggpsppv.......vtvsvd
                   f+g++  + C+v++++    ++C  P+++++  ++  + ++++++ + ++
   mKIAA0463   713 FNGKESvnVCTVVNTTT---LTCLAPSLTsDYRPGLDtverpdeFGFLFN 759  

                   gggsgdgrssspvtFtYv<-*
                   +++   +++ + + F Y+   
   mKIAA0463   760 NVQ--SLLIYNDTKFIYY    775  

TIG: domain 4 of 4, from 778 to 871: score 46.8, E = 4.7e-10
                   *->PvItsisP.ssgplsGGteiTitGsnlgsgsePrirk.ntfededik
                      P+++ +sP+     ++G+ i+++G+nl  ++ + + +++t       
   mKIAA0463   778    PTFELLSPtGILDQKPGSPIILKGKNLCPPASGGAKLnYT------- 817  

                   VtfggtpvpCdvissssstqivCktPpva.ggpsppvvtvsvdggg.sgd
                   V +g+tp  C+v++s+  tq+ C+ P+++++++    v+v+v+g   s++
   mKIAA0463   818 VMIGETP--CTVTVSE--TQLLCEPPNLTgQHK----VMVHVGGMVfSPG 859  

                   grssspvtFtYv<-*
                    +s  + +   +   
   mKIAA0463   860 SVSVISDSLLTL    871  

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