hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg09026/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0450  ( 1592 res)   mbg09026

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PLCXc    Phospholipase C, catalytic domain (part); do   266.8    1.7e-75   1
PLCYc    Phospholipase C, catalytic domain (part); do   202.7    3.4e-56   1
C2       Protein kinase C conserved region 2 (CalB)      86.6    3.1e-21   1
EFh      EF-hand, calcium binding motif                  48.7    7.6e-10   2
PH       Pleckstrin homology domain.                     37.2    2.1e-06   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PH         1/1      22   131 ..     1    82 []    37.2  2.1e-06
EFh        1/2     147   175 ..     1    29 []    27.5   0.0019
EFh        2/2     183   212 ..     1    29 []    21.4     0.13
PLCXc      1/1     320   465 ..     1   182 []   266.8  1.7e-75
PLCYc      1/1     627   741 ..     1   119 []   202.7  3.4e-56
C2         1/1     760   868 ..     1    92 []    86.6  3.1e-21

Alignments of top-scoring domains:
PH: domain 1 of 1, from 22 to 131: score 37.2, E = 2.1e-06
                   *->vikeGwLlkks..k.swkkryfvLfn..gvLlyyksk.kpkgsipLs
                         eG+ ++k +++++   r+ +L++++++L +  s++  k +i+++
   mKIAA0450    22    AMQEGTQMVKLrgSsKGLVRFYYLDEhrSCLRWRPSRkNEKAKISID 68   

                   gc.svre.p.................cFeivt.dr..tlllqAeseeere
                   ++++v+e+  ++   + ++++ +++ cF i++++++++l l  +s+ee++
   mKIAA0450    69 SIqEVSEgRqseifqrypdssfdpncCFSIYHgSHreSLDLVSPSSEEAR 118  

                   eWvealqsaiaka<-*
                    Wv+ l+ ++a     
   mKIAA0450   119 TWVTGLRYLMAGI    131  

EFh: domain 1 of 2, from 147 to 175: score 27.5, E = 0.0019
                   *->elkeaFrefDkDgdGkIdfeEfkallksl<-*
                       lk+ F+e+Dk+gdG ++  E ++ll++l   
   mKIAA0450   147    WLKQTFDEADKNGDGSLSISEVLQLLHKL    175  

EFh: domain 2 of 2, from 183 to 212: score 21.4, E = 0.13
                   *->elkeaFrefDkD.gdGkIdfeEfkallksl<-*
                       +k++Fre+D+D++ G++ feEf+a+ k++   
   mKIAA0450   183    RVKQMFREADTDdHQGTLGFEEFCAFYKMM    212  

PLCXc: domain 1 of 1, from 320 to 465: score 266.8, E = 1.7e-75
                   *->qDmdkPLshYfInsSHNsGtfkidiFPFGLDAPEKLRLPPYVTFLLR
                      qDm++PLshYfI sSHN                              
   mKIAA0450   320    QDMTQPLSHYFITSSHN------------------------------ 336  

                   FTYLtgkQlwgessvegYiqaLkaGcRcvELDcwdgpdgePviyHGhTft
                    TYL g+Ql + s v +Y  +L+aGcRcvE DcwdgpdgeP+++HG+T+t
   mKIAA0450   337 -TYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLT 385  

                   skikLsdVleaIKkfAFvtSpyPEFvIlSLenHcspdqQakmaqmfkeiF
                   ski ++dV+e+I+k+AF++ +yP  vIlS+enHcs+ qQ+kmaq+++ i+
   mKIAA0450   386 SKILFKDVIETINKYAFIKNEYP--VILSIENHCSVVQQKKMAQYLTDIL 433  

                   gdlLytkPltsseeypgsnLPsPeqLkgKILLkgK<-*
                   gd+L   +l s+++++   LPsP++LkgKIL+kgK   
   mKIAA0450   434 GDKL---DLSSVSSEDATMLPSPQMLKGKILVKGK    465  

PLCYc: domain 1 of 1, from 627 to 741: score 202.7, E = 3.4e-56
                   *->lseLvsycapvkFrsfelaeekdnafyemsSfsEtkaakkllekapt
                      ls+Lv y ++v  + +e +  +   ++++sSfsEtk a ++l+++pt
   mKIAA0450   627    LSDLVKYTKSVGTHDVEIEVVS---SWQVSSFSETK-AHQILQQKPT 669  

                   dfvryNqrqLsRvYPkGtRvDSSNYnPqvfWnaGcQMVALNfQTpDkaMq
                   + +r+Nq+qLsR+YP+  RvDSSNYnPq+fWnaGcQMVALN+Q  ++++q
   mKIAA0450   670 QYLRFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQ 719  

                   lNqGmFraNGgCGYVLKPefLR<-*
                   lN ++F+aNG CGYVLKP ++    
   mKIAA0450   720 LNRAKFSANGDCGYVLKPQCMC    741  

C2: domain 1 of 1, from 760 to 868: score 86.6, E = 3.1e-21
                   *->tLtvkiisArnLp..............DPYVkvs...........kT
                      +L ++iis+++Lp+++++  ++++   DP+V+v+  + + + ++ +T
   mKIAA0450   760    QLALRIISGQQLPkprdsvlgdrgeiiDPFVEVEviglpvdcskeQT 806  

                   kvvkktlsgfNPvWnEesetFeFevpp...s.LeieVyDk.....dfiGr
                   +vv +++  fNP W+E   t++F+v+ ++ + +++ V+D+++ ++dfiG+
   mKIAA0450   807 RVVDDNG--FNPMWEE---TLVFTVHMpeiAlVRFLVWDHdpigrDFIGQ 851  

                   vtippnnahqhsadglihlsell.ggrh.kl<-*
                    t+               +s++++g+rh  l   
   mKIAA0450   852 RTLA--------------FSSIMpGYRHvYL    868  

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