hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg09026/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0450  ( 1592 res)   mbg09026

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PI-PLC-X Phosphatidylinositol-specific phospholipase    248.4    9.8e-71   1
PI-PLC-Y Phosphatidylinositol-specific phospholipase    173.4    3.6e-48   1
C2       C2 domain                                       96.3    6.2e-25   1
efhand   EF hand                                         34.8      2e-06   2
PH       PH domain                                       32.8    7.8e-06   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PH         1/1      22   129 ..     1    92 []    32.8  7.8e-06
efhand     1/2     147   175 ..     1    29 []    28.7  0.00013
efhand     2/2     183   212 ..     1    29 []     6.4       25
PI-PLC-X   1/1     321   466 ..     1   153 []   248.4  9.8e-71
PI-PLC-Y   1/1     626   741 ..     1   128 []   173.4  3.6e-48
C2         1/1     761   853 ..     1    88 []    96.3  6.2e-25

Alignments of top-scoring domains:
PH: domain 1 of 1, from 22 to 129: score 32.8, E = 7.8e-06
                   *->vikeGwLlkkg.gkkswkkRyfvLfn..dvLlyykdkkkkpkgsipL
                       + eG  ++k +g ++   R+  L +++++L +  ++ k+ k +i++
   mKIAA0450    22    AMQEGTQMVKLrGSSKGLVRFYYLDEhrSCLRWRPSR-KNEKAKISI 67   

                   sgi.qvekvpdn...........krkncFeirt.dr.etlllqaeseeer
                   ++i++v +   ++  ++ ++++ + ++cF i +++++e+l l  +s+ee+
   mKIAA0450    68 DSIqEVSEGRQSeifqrypdssfDPNCCFSIYHgSHrESLDLVSPSSEEA 117  

                   keWvkaiqsair<-*
                   ++Wv+ ++++++   
   mKIAA0450   118 RTWVTGLRYLMA    129  

efhand: domain 1 of 2, from 147 to 175: score 28.7, E = 0.00013
                   *->elkeaFkefDkDgDGkIsfeEfkaalkkl<-*
                       lk+ F+e+Dk+gDG +s+ E +++l+kl   
   mKIAA0450   147    WLKQTFDEADKNGDGSLSISEVLQLLHKL    175  

efhand: domain 2 of 2, from 183 to 212: score 6.4, E = 25
                   *->elkeaFkefDk.DgDGkIsfeEfkaalkkl<-*
                      ++k++F+e+D++D+ G++ feEf+a++k++   
   mKIAA0450   183    RVKQMFREADTdDHQGTLGFEEFCAFYKMM    212  

PI-PLC-X: domain 1 of 1, from 321 to 466: score 248.4, E = 9.8e-71
                   *->dmsiPLsHYfisSshntYLtgkQlwGkssvesYrqqLdaGcRcvELD
                      dm +PLsHYfi+SshntYL g+Ql ++s v +Y  +L+aGcRcvE D
   mKIAA0450   321    DMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVD 367  

                   cwdGkpddepiIyHGhtltleiklkdVleaIkdfafkPtSpyPvIlSlen
                   cwdG pd+epi+ HG+tlt++i++kdV+e+I ++af    +yPvIlS+en
   mKIAA0450   368 CWDG-PDGEPIVHHGYTLTSKILFKDVIETINKYAFI-KNEYPVILSIEN 415  

                   HcnsddqQrkmakyfkeiFgdmLltkPtldslttepglpLPslkdlrgKI
                   Hc++  qQ+kma+y+ +i+gd+L    +  + +t     LPs+ +l+gKI
   mKIAA0450   416 HCSVV-QQKKMAQYLTDILGDKLDLSSVSSEDATM----LPSPQMLKGKI 460  

                   LLknkk<-*
                   L+k+kk   
   mKIAA0450   461 LVKGKK    466  

PI-PLC-Y: domain 1 of 1, from 626 to 741: score 173.4, E = 3.6e-48
                   *->ElsnLvnYiqsikFrsFelsGeekntsyeisSFsErkvkakkllkes
                       ls+Lv Y +s++    e+       s ++sSFsE+  ka + l++ 
   mKIAA0450   626    ALSDLVKYTKSVGTHDVEIE---VVSSWQVSSFSET--KAHQILQQK 667  

                   pvefVkyNkrqLsRvYPkGtRvDSSNfmPqvfWnaGCQmVALNfQTsDlp
                   p +  ++N++qLsR+YP   RvDSSN++Pq+fWnaGCQmVALN+Q+ +  
   mKIAA0450   668 PTQYLRFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRM 717  

                   mqiNdGmFeyNggqPdGsfksGYlLKPeflR<-*
                   +q+N ++F++Ng        +GY+LKP ++    
   mKIAA0450   718 LQLNRAKFSANGD-------CGYVLKPQCMC    741  

C2: domain 1 of 1, from 761 to 853: score 96.3, E = 6.2e-25
                   *->LrVtvieAknLppkDf.....kngksDPYVkvslggdkkd.qkkkTk
                      L +++i+++ Lp+  ++  ++++  +DP+V+v++ g ++d +k +T+
   mKIAA0450   761    LALRIISGQQLPKPRDsvlgdRGEIIDPFVEVEVIGLPVDcSKEQTR 807  

                   vikkt.lNPvWNEtFtFevpppdlqetLeieVyDydrfgrddflGevs<-
                   v++++++NP W+Et++F v+ p+ +  +++ V+D+d +g  df+G+ +  
   mKIAA0450   808 VVDDNgFNPMWEETLVFTVHMPEIAL-VRFLVWDHDPIG-RDFIGQRT   853  

                   *
                    
   mKIAA0450     -   -    

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