hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbp/mbp02223/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0447  ( 414 res)   mbp02223

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
DUF250   Domain of unknown function, DUF250             153.4    3.9e-42   1
DUF6     Integral membrane protein DUF6                   8.0       0.47   2

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
DUF6       1/2      92   224 ..     1   128 []    -1.9      1.5
DUF250     1/1     233   378 ..     1   164 []   153.4  3.9e-42
DUF6       2/2     242   378 ..     1   128 []    17.9     0.15

Alignments of top-scoring domains:
DUF6: domain 1 of 2, from 92 to 224: score -1.9, E = 1.5
                   *->fiWalytvfskkller........ispltltawrfliagilllilll
                      f++++ t+f  k + +  +++++ ++++ +++  ++ +   + ++ l
   mKIAA0447    92    FFFSFCTLFLNKYILSllegepsmLGAVQMLSTTLIGCVKIFVPCCL 138  

                   fllkgppllallslk.ilallylgilgtalgyllyfyalkyvsaskasvl
                   +  k +   ++++++ i   l++g+   + + +l + +lk+v +s+a  +
   mKIAA0447   139 YQHKTR---LSYPPNfIMTMLFVGLM-RFATVVLGLVSLKNVAVSFAETV 184  

                   tslsPvftlilsvllLgEkltlkqllGivlillGvllisl<-*
                    s +P+ft+i+s  +LgE  +l+  l+++ +++G++l +    
   mKIAA0447   185 KSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTA    224  

DUF250: domain 1 of 1, from 233 to 378: score 153.4, E = 3.9e-42
                   *->GfilalaasllfaLrlilsqkllkkklkkgtklnplellyylspvaf
                      Gf +al+++++ +L++++s+kll+++   ++  +  el++y+s +a+
   mKIAA0447   233    GFSAALSTNIMDCLQNVFSKKLLSGD---KYRFSAPELQFYTSAAAV 276  

                   ivllpgllfvegfklnkfilkakssdlseEmeFkkGktqryvlllllsgv
                   ++l+p++ f+ +  +++++ k++s+            +q +vllll +g 
   mKIAA0447   277 ALLIPAWTFFMDIPVIGRSGKSFSY------------SQDIVLLLLTDGA 314  

                   lafllnlsaflllgrtSplTysVagtvKrvvvivlsviiFgFmDdpvtpl
                   l++l+ ++a+ l+g++Sp+T+sVa+tvK+++ i+ls+i+Fg   +++t l
   mKIAA0447   315 LFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSIIVFG---NKITSL 361  

                   nilGlaiAlaGvvlYsy<-*
                    ++G+++  +Gv+lY+    
   mKIAA0447   362 SAIGTILVTLGVLLYNK    378  

DUF6: domain 2 of 2, from 242 to 378: score 17.9, E = 0.15
                   *->fiWalytvfskkller....ispltltawrfliagilllilllfllk
                      ++  l  vfskkll+ ++ ++s+++l ++ ++ a +ll++   f++ 
   mKIAA0447   242    IMDCLQNVFSKKLLSGdkyrFSAPELQFYTSAAAVALLIPAWTFFMD 288  

                   gppl...lallslk.ilallylgilgtalgyllyfya.lkyvsaskasvl
                   +p ++++ +++s ++ + ll+l   + +  ++   ya + ++s+ + sv 
   mKIAA0447   289 IPVIgrsGKSFSYSqDIVLLLLTDGALFHLQSVTAYAlMGKISPVTFSVA 338  

                   tslsPvftlilsvllLgEkltlkqllGivlillGvllisl<-*
                   + +  ++++ ls++++g k+t +  +G++l+ lGvll +    
   mKIAA0447   339 STVKHALSIWLSIIVFGNKITSLSAIGTILVTLGVLLYNK    378  

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