hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpg/mpg00622/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0433  ( 1132 res)   mpg00622

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N 
--------        -----------                             -----    ------- ---
Acid_phosphat_A Histidine acid phosphatase              349.8   2.9e-101   1
PGAM            Phosphoglycerate mutase family          -10.3       0.17   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
PGAM              1/1     489   662 ..     1   216 []   -10.3     0.17
Acid_phosphat_A   1/1     388   903 ..     1   395 []   349.8 2.9e-101

Alignments of top-scoring domains:
PGAM: domain 1 of 1, from 489 to 662: score -10.3, E = 0.17
                   *->rlyLvRHGe....tewlNaenlqeegrisqlqGwt.........Lte
                      +l  + HG +++++e        +++r            + +++Lt+
   mKIAA0433   489    QLTYLPHGCpktsSE--EE----DNRR---EEPSLllvlkwggeLTP 526  

                   kGreQAralgkrllqLk......................vqavesrtasl
                    Gr QA++lg++   ++   ++++++  + ++ +  + +           
   mKIAA0433   527 AGRVQAEELGRA---FRcmypggqgdyagfpgcgllrlhS---------- 563  

                   klseelgipfda.iysSPlkRArqTAeiilaelLkaelgnpedrwdeglk
                           + d++iy+S+  R + TA++ +a+    +l            
   mKIAA0433   564 ------TYRHDLkIYASDEGRVQMTAAA-FAK----GLL----------- 591  

                   tklpvivdprLrErdfGfedWsrceeGltfaelkekyp......eyr.wr
                                      ++   e G  ++ l ++  + + ++ +++  
   mKIAA0433   592 -------------------AL---E-GELTPILVQMVKsanmngLLDsDS 618  

                   edpadfrppgaakredeiegvPgGEeasladvaaRv.aaleeli......
                   +                          sl   ++Rv+a l e+++++++ 
   mKIAA0433   619 D--------------------------SLSSCQQRVkARLHEILqkdrdf 642  

                   ........hpgenviliVsHGgviral<-*
                   + ++ ++  p +++        vi+++   
   mKIAA0433   643 taedyeklTPSGSI-------SVIKSM    662  

Acid_phosphat_A: domain 1 of 1, from 388 to 903: score 349.8, E = 2.9e-101
                   *->eLefVqvvfRHGdRtPtksypkdikaeidkllsa.............
                      eL++V++v+RHGdRtP+++++++++++++++l+++ ++ ++++ + +
   mKIAA0433   388    ELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEkcdgyksgklklk 434  

                   .....................................alalegklsflgd
                   ++++ ++  +  ++   + +++++++ ++++++ ++ +++le++++f+g+
   mKIAA0433   435 kpkqlqevldiarqllmelgqnndseieenkskleqlKTVLEMYGHFSGI 484  

                   y.ylvpdp.....................lqwplgwGqeLTpeGreqafe
                   ++++++++ +++ ++++++++++++++++l   l+wG+eLTp+Gr+qa+e
   mKIAA0433   485 NrKVQLTYlphgcpktsseeednrreepsLLLVLKWGGELTPAGRVQAEE 534  

                   lGrylRqrYvedl.........gLlpdeynarkevyirstdvdRtlaSAq
                   lGr +R++Y++++++  + ++ gLl+ ++++r++++i+++d++R++++A+
   mKIAA0433   535 LGRAFRCMYPGGQgdyagfpgcGLLRLHSTYRHDLKIYASDEGRVQMTAA 584  

                   aflaGlfppdg...................lvdvwndlldwqpipvhtip
                   af++Gl+ + +++ ++   +  ++ + ++ l+++ ++l++ q   +  ++
   mKIAA0433   585 AFAKGLL-ALEgeltpilvqmvksanmnglLDSDSDSLSSCQQRVKARLH 633  

                   eakkaldnllll.ynsCpafee.....lqepllvekrvdeelaklladyl
                   e+ +++ ++ + +y+  +   + +  ++++++++  ++++++ +l++ + 
   mKIAA0433   634 EILQKDRDFTAEdYEKLTPSGSisvikSMHLIKNPVKTCDKVYSLIQSLT 683  

                   epiakrlsql...qllcltGgtnltaddvwalldlclfetn.krdgspfp
                    +i+ r++++++ + + + ++t  +++ +w++l + + ++n+ +d+s++p
   mKIAA0433   684 SQIRYRMEDPksaDIQLYHSETLELMLRRWSKLEKDFKTKNgRYDISKIP 733  

                   dlftelkqyellhleylllsdLseyyglsk.LaDfvipQEYgignelarl
                   d+++++k y+++h+  l+l++  e+y+lsk LaD+vipQEYgi++ +++ 
   mKIAA0433   734 DIYDCIK-YDVQHNGSLKLENTMELYRLSKaLADIVIPQEYGITKAEKLE 782  

                   qGgpllnellkrltnklvgdk.....T.tnrtl.snpatfpldrklylyf
                   ++ +++ +l+++++++l++++++++ +++++ ++++++++ ++ +++lyf
   mKIAA0433   783 IAKGYCTPLVRKIRSDLQRTQdddtvNkLHPVYsRGVLSPERHVRTRLYF 832  

                   aHDttiapllaaLre.Glfddl.gldkp.fqdsfksseepPyaarlvfEl
                   ++++++++ll+ Lr++ l+dd++++++ +++d++ +  e++y++++v++l
   mKIAA0433   833 TSESHVHSLLSILRYgALCDDSkDEQWKrAMDYLNVVNELNYMTQIVIML 882  

                   yqcddgk.a.tgeyyVrvlyn<-*
                   y++++++ +++++++V+++++   
   mKIAA0433   883 YEDPNKDlSsEERFHVELHFS    903  

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