hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg17696/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0398  ( 467 res)   mbg17696

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N 
--------        -----------                             -----    ------- ---
Pox_MCEL        mRNA capping enzyme                     662.9   1.6e-195   1
Methyltransf_11 Methyltransferase domain                 23.1     0.0046   1
Methyltransf_12 Methyltransferase domain                 20.1      0.042   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
Methyltransf_12   1/1     193   305 ..     1   100 []    20.1    0.042
Methyltransf_11   1/1     193   307 ..     1    99 []    23.1   0.0046
Pox_MCEL          1/1     127   467 .]     1   563 []   662.9 1.6e-195

Alignments of top-scoring domains:
Methyltransf_12: domain 1 of 1, from 193 to 305: score 20.1, E = 0.042
                   *->LdiGcGtGrllaalleallnpgaeytgvDiSp.aleiaaaaerladl
                      Ld+GcG G+ l  + +    + +++++ Di   ++       + +++
   mKIAA0398   193    LDLGCGKGGDLLKWRKG---RISRLVCADIADiSM-------KQCQQ 229  

                   gl.va.rvrldvldlidedp..................sfDvvvafnvLh
                   + ++ ++ r ++   + e ++ + +++   ++ ++++  fDv  + ++ h
   mKIAA0398   230 RYeDMrCRRDNEHIFSAEFItadcskellvekfrdpemYFDVCSCQFACH 279  

                   hl..dpedpravLrnlrrlLkPGGvl<-*
                   +  +++ + + +Lrn+   L PGG++   
   mKIAA0398   280 YSfeSQVQADTMLRNACGRLNPGGYF    305  

Methyltransf_11: domain 1 of 1, from 193 to 307: score 23.1, E = 0.0046
                   *->LDvGcGtGllaraLarrvgpgarvtGvDlspemlalArerapeagle
                      LD+GcG G  ++ +++     +r+++ D+ + + +++++r+++   +
   mKIAA0398   193    LDLGCGKGGDLLKWRKG--RISRLVCADIADISMKQCQQRYEDMRCR 237  

                   n.........fvvgD......aedLPfpDesFDlVvssevlhhl...aed
                   +++++  + +f+ +D +++  +e+   p+ +FD++ + ++ h+  ++   
   mKIAA0398   238 RdnehifsaeFITADcskellVEKFRDPEMYFDVCSCQFACHYSfesQVQ 287  

                   peralrEiaRVLKPGGklvi<-*
                    +  lr++   L PGG+++    
   mKIAA0398   288 ADTMLRNACGRLNPGGYFIG    307  

Pox_MCEL: domain 1 of 1, from 127 to 467: score 662.9, E = 1.6e-195
                   *->egeaeteknitdvVaaHLpaQPEGVvLFYnerDEKitDGviLLDkes
                      ++ +++e++++++VaaH           Yne+            +e+
   mKIAA0398   127    QKLQKLEEGHSSAVAAH-----------YNEL------------QEV 150  

                   gidlkkRqdSpIdqavNiiyrymssePvifgedsiFlefkkFsNDkgfpk
                   g  l+kR++S+I++                                    
   mKIAA0398   151 G--LAKRSQSRIFY------------------------------------ 162  

                   EygtgklvlndgvrYlNnIycLeFkNiHnrvGikivvvPikfIvEFSflg
                                                                     
   mKIAA0398     - -------------------------------------------------- -    

                   elikpridktmkylfknYYGNqlkVilehlrdqeikvGLDtvGiDYLYdv
                                                                     
   mKIAA0398     - -------------------------------------------------- -    

                   FkedklsdvgknlaNdkvrlnpdvsyftnkrtRGPLrnFNNwIKslLIse
                                                      LrnFNNwIKs+LI+e
   mKIAA0398   163 -----------------------------------LRNFNNWIKSILIGE 177  

                   yasKtfqeksmGpkrkVLdldCGKGGDLlKydkagIsgligtDIaevSie
                   +++K++q+k+  ++++VLdl+CGKGGDLlK++k++Is+l+++DIa++S++
   mKIAA0398   178 ILEKVRQRKT--RDITVLDLGCGKGGDLLKWRKGRISRLVCADIADISMK 225  

                   qaqeRYtnsndlnsrskskyykfdFeaefitgDcflesvrevleppfPqk
                   q+q+RY   +d+++r++++++   F+aefit+Dc +e++ e++++p    
   mKIAA0398   226 QCQQRY---EDMRCRRDNEHI---FSAEFITADCSKELLVEKFRDP---- 265  

                   erkFPvDivScQFAiHYSFeseekArtiLrNvaelLasGGkfIgTtpDgd
                   e++F  D++ScQFA+HYSFes+ +A+t+LrN++ +L++GG+fIgTtp+++
   mKIAA0398   266 EMYF--DVCSCQFACHYSFESQVQADTMLRNACGRLNPGGYFIGTTPNSF 313  

                   fIikkLtakktevekksfGNsvYkvsFekeYskedtkfrPpfGqkyvfnL
                   ++i++L+a    +e++sfGN++Y+v+F+k+      +++P+fG+ky+fnL
   mKIAA0398   314 ELIRRLEA----SETESFGNEIYTVKFQKK------GNYPLFGCKYDFNL 353  

                   edavtdvpEYlVpFetLvelaeeYgleLvdkktFadiyeEeikkerskml
                   e++v dvpE+lV+F+ L+e+a++Y+++L++kktF+++yeE+ik++++kml
   mKIAA0398   354 EGVV-DVPEFLVYFPLLTEMAKKYNMKLIYKKTFLEFYEEKIKNNENKML 402  

                   lkrmsgLesrkatkNsKLvSeknddyehavsnnffelnrlalgtlegdEw
                   lkrm++Le+++a++NsKL+Sek++dy+ha+++++++++rl+lgtl+++Ew
   mKIAA0398   403 LKRMQALEQYPAHENSKLASEKVGDYTHAAEYLKKSQVRLPLGTLSKSEW 452  

                   EAalnlYlvFvFeKrk<-*
                   EA++ +YlvF+FeK++   
   mKIAA0398   453 EATS-IYLVFAFEKQQ    467  

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