hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg03948/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0382  ( 1553 res)   mbg03948

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGEF   Guanine nucleotide exchange factor for Rho/R   234.2    1.1e-65   1
PDZ      Domain present in PSD-95, Dlg, and ZO-1/2.      79.5      4e-19   1
PH       Pleckstrin homology domain.                     35.4    7.9e-06   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PDZ        1/1      89   157 ..     1    80 []    79.5    4e-19
RhoGEF     1/1     801   986 ..     1   211 []   234.2  1.1e-65
PH         1/1    1030  1144 ..     1    82 []    35.4  7.9e-06

Alignments of top-scoring domains:
PDZ: domain 1 of 1, from 89 to 157: score 79.5, E = 4e-19
                   *->gglGfsivg..gifvssvvpGspAakaGrkslglLkvGDvIleVNGe
                      +g+G++++g++++fv sv+++++A +aG      ++ GD+I++VNG 
   mKIAA0382    89    NGFGLTVSGdnPVFVQSVKEDGAAMRAG------VQTGDRIIKVNG- 128  

                   tsvegltheeavdllkkaggggvGekvtLtvlRgg<-*
                   t v+   h+e+v+l+++      G+ v Ltv+ ++   
   mKIAA0382   129 TLVTHSNHLEVVKLIRS------GSYVALTVQGRP    157  

RhoGEF: domain 1 of 1, from 801 to 986: score 234.2, E = 1.1e-65
                   *->vlkELlqTErnYVrdLkilvevflkpLkkeakssllpllspdevktl
                      v++EL+ TEr++Vr+Lk+l++vf+++ ++e+      +lsp+e++++
   mKIAA0382   801    VINELFYTERAHVRTLKVLDQVFYQRVSREG------ILSPSELRKI 841  

                   FgpNieeiyefHrrFLdeLeerveewllskdlKsernsviedsgerigdv
                   F+ N+e+i+++H+ + +++++ ++  +         +svi+++ge++   
   mKIAA0382   842 FS-NLEDILQLHVGLNEQMKAVRKRNE---------TSVIDHIGEDLLIW 881  

                   FlklfsaeeffkiYseYcsnhpdalellkkLmkkkknpaFqkflkeiesk
                   F+++  +e+++++ +++csn+p ale++k    +kk+++F++f++ +es+
   mKIAA0382   882 FSGP-GEEKLKHAAATFCSNQPFALEMIKS--RQKKDSRFHTFVQDAESN 928  

                   pncrsksearltLeslLikPvQRltkYpLLLkellkhtppdhedredLkk
                   p cr     rl+L++++++ +QRltkYpLLL ++ k+t++ +++re++kk
   mKIAA0382   929 PLCR-----RLQLKDIIPTQMQRLTKYPLLLDNIAKYTEW-PPEREKVKK 972  

                   AleaikelasqvNe<-*
                   A +++++++++vN+   
   mKIAA0382   973 AADHCRQILNYVNQ    986  

PH: domain 1 of 1, from 1030 to 1144: score 35.4, E = 7.9e-06
                   *->vikeGwLlkks.k.swkkryfvLfngvLlyyksk.............
                      +i+eG L +k ++++  + y  L ++ L++ ++ +++   + +++  
   mKIAA0382  1030    MIHEGPLVWKVnRdKSIDLYTLLLEDILVLLQKQddrlvlrchskil 1076 

                   ........kpkgsipLsgcsvre.p.....cFeivt.dr...tlllqAes
                    ++ +++++ +++i Ls++ vr  + +++  F i+++d++ + ++l A +
   mKIAA0382  1077 astadskhTFSPVIKLSTVLVRQvAtdnkaLFVISMsDNgaqIYELVAQT 1126 

                   eeereeWvealqsaiaka<-*
                    +e++ W + +++++a+    
   mKIAA0382  1127 VSEKTVWQDLICRMAASV    1144 

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