hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg03948/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0382  ( 1553 res)   mbg03948

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGEF   RhoGEF domain                                   78.2    1.7e-19   1
PDZ      PDZ domain (Also known as DHR or GLGF)          50.5    3.6e-11   1
PH       PH domain                                       15.2       0.95   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PDZ        1/1      81   154 ..     1    82 []    50.5  3.6e-11
RhoGEF     1/1     801   986 ..     1   207 []    78.2  1.7e-19
PH         1/1    1030  1142 ..     1    92 []    15.2     0.95

Alignments of top-scoring domains:
PDZ: domain 1 of 1, from 81 to 154: score 50.5, E = 3.6e-11
                   *->evtlekevkrgglGfsikggsdkgivvsevlpGsgaAeagGrLkeGD
                       v+++k    +g+G++++g  d++++v +v ++ gaA ++G  + GD
   mKIAA0382    81    CVIIQK--DDNGFGLTVSG--DNPVFVQSVKED-GAAMRAG-VQTGD 121  

                   qIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                   +I++vNG+ v+   h+++v+++++ +   v+Lt++   
   mKIAA0382   122 RIIKVNGTLVTHSNHLEVVKLIRSGS--YVALTVQ    154  

RhoGEF: domain 1 of 1, from 801 to 986: score 78.2, E = 1.7e-19
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskpvltpddietiF
                      v++El+ TE++ vr+L  ld+v+ +++ ++      +l+p ++  iF
   mKIAA0382   801    VINELFYTERAHVRTLKVLDQVFYQRVSREG-----ILSPSELRKIF 842  

                   sNiediyefhreFLkssLearisssqfedlDekkiepsaqrlGdlFlklk
                   sN+edi+++h+ +    ++a+                +++++  + ++l+
   mKIAA0382   843 SNLEDILQLHVGLNE-QMKAVRKR------------NETSVIDHIGEDLL 879  

                   epflqv........YgeYcsnkpyAqelleklrqaasnpqFaefldevea
                     f+++++++ ++ ++ +csn+p A e++++    ++   F  f+++ e 
   mKIAA0382   880 IWFSGPgeeklkhaAATFCSNQPFALEMIKS--RQKKDSRFHTFVQDAES 927  

                   ssntgAkddavkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedqpdre
                   ++++       +l L + +   +qR+++YpLLL+ + k+t      p+re
   mKIAA0382   928 NPLCR------RLQLKDIIPTQMQRLTKYPLLLDNIAKYTE---WPPERE 968  

                   dLkkaldllqdlaksiNe<-*
                     kka d  + +++++N+   
   mKIAA0382   969 KVKKAADHCRQILNYVNQ    986  

PH: domain 1 of 1, from 1030 to 1142: score 15.2, E = 0.95
                   *->vikeGwLlkkg.gkkswkkRyfvLfndvLlyykdkk...........
                       i+eG L  k ++ ks   + + L +   l+ k +++   + +++  
   mKIAA0382  1030    MIHEGPLVWKVnRDKSIDLYTLLLEDILVLLQKQDDrlvlrchskil 1076 

                   .......kkpkgsipLsgiqvekvpdnkrkncFeirt.dr..etlllqae
                    ++ +++++   +i Ls++ v+ v +  +k  F+i+++d++ + ++l a 
   mKIAA0382  1077 astadskHTFSPVIKLSTVLVRQVATD-NKALFVISMsDNgaQIYELVAQ 1125 

                   seeerkeWvkaiqsair<-*
                   +  e++ W + i++ ++   
   mKIAA0382  1126 TVSEKTVWQDLICRMAA    1142 

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