hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg14564/w3open/interpro/cnk_1/seq.in
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query:  mKIAA0351  ( 537 res)   mbg14564

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RasGEF   Guanine nucleotide exchange factor for Ras-l   301.1      8e-86   1
PH       Pleckstrin homology domain.                     60.4    2.2e-13   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RasGEF     1/1      86   313 ..     1   261 []   301.1    8e-86
PH         1/1     412   525 ..     1    82 []    60.4  2.2e-13

Alignments of top-scoring domains:
RasGEF: domain 1 of 1, from 86 to 313: score 301.1, E = 8e-86
                   *->lllldpeelAeQLTlldfelFrkIepsEllgsvwgkrskkspsplap
                      +l++ pee+A                 El ++ w+k++k+s++p   
   mKIAA0351    86    VLKVTPEEFA-----------------ELASCGWSKKEKHSLAP--- 112  

                   qnleafierfNevsnwVateIlkqttlkpkkRaevlskFIkVAkhcreLn
                    n+ af++rfN+vs+wV+ eIl+++t  +k Rae+ls+F+k+Ak+++eLn
   mKIAA0351   113 -NVVAFTRRFNQVSFWVVREILTAQT--LKIRAEILSHFVKIAKKLLELN 159  

                   NFnSlmAIvsaLssspIsRLkkTWeklsskykklfeeLeelldpserNfk
                   N++Slm++vsaL+s+pI RL+kTW+ l++k+k++fe+L++l++ + +N+k
   mKIAA0351   160 NLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKE-DNYK 208  

                   nYReaLkscnkspnvqppcvPflGvyLkDLtfidegnpdflengtkglvN
                   + R++++s++     ++p +P+lG+yL DL++id ++p         ++N
   mKIAA0351   209 RTRDYIRSLK-----MVPSIPYLGIYLLDLIYIDSAYPASGS----IMEN 249  

                   FeKrrkiakilreirqlqsacqpynlkpnrndiqellrasrplevlpeee
                    +  +++ +ilr i  lq++c++++l+   +++q++l+++r++e l+++ 
   mKIAA0351   250 EQRSNQMNNILRIIADLQVSCSYDHLTTL-PHVQKYLKSVRYIEELQKFV 298  

                   .delyelSlriEPrv<-*
                   +d+ y+lSlriEP +   
   mKIAA0351   299 eDDNYKLSLRIEPGS    313  

PH: domain 1 of 1, from 412 to 525: score 60.4, E = 2.2e-13
                   *->vikeGwLlkks.........k.swkkryfvLfngvLlyyksk.....
                      +++eG L++k+  + ++++ ++sw+++++vL + +Llyy  k+ +++
   mKIAA0351   412    PTMEGPLRRKTllkegrkpaLsSWTRYWVVLSGATLLYYGAKslrgt 458  

                   .......kpkgsipLsgcsvre.p......cFeivt.dr..tlllqAese
                   ++++ +++p +++++ g  v+ ++++++++ F++ ++d+++++ +q+ s 
   mKIAA0351   459 drkhyksTPGKKVSIVGWMVQLpDdpehpdIFQLNNpDKgnVYKFQTGSR 508  

                   eereeWvealqsaiaka<-*
                    ++  W ++l +a++++   
   mKIAA0351   509 FHAILWHKHLDDACKSS    525  

//