hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg14564/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0351  ( 537 res)   mbg14564

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RasGEF   RasGEF domain                                  135.5    9.5e-37   1
PH       PH domain                                       68.2    1.7e-16   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RasGEF     1/1      77   261 ..     1   227 []   135.5  9.5e-37
PH         1/1     412   523 ..     1    92 []    68.2  1.7e-16

Alignments of top-scoring domains:
RasGEF: domain 1 of 1, from 77 to 261: score 135.5, E = 9.5e-37
                   *->LllDplelAkQLTLlEhelfkkItpfefLgsKmKHEGPqvWgkksfk
                       ++D++       +++     k+tp+ef  +        +W+kk   
   mKIAA0351    77    KSYDAV-------VFDVL---KVTPEEFAEL-----ASCGWSKK--- 105  

                   gkeerspnidktiknfNqltnfvsetIlkqeFPTNPEFSKkvdpkkRaev
                   +k   +pn  +++++fNq++ +v ++Il ++           + k Rae+
   mKIAA0351   106 EKHSLAPNVVAFTRRFNQVSFWVVREILTAQ-----------TLKIRAEI 144  

                   iqkfIqVAdhcReLnNFnSllaIisALysspIyRLkkTWekvppqslklI
                   +++f+ +A +++eLnN+ Sl++++sAL+s+pI+RL+kTW++++++++ + 
   mKIAA0351   145 LSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTT- 193  

                   feeLnkLmdsdrNfsnyRelLksigplappnLdddfvraPCVPFfGvYLs
                   fe+L  Lm+ ++N++++R+ ++s   +            P +P++G YL 
   mKIAA0351   194 FEKLDYLMSKEDNYKRTRDYIRSLKMV------------PSIPYLGIYLL 231  

                   DLtfleeGnp...dyleekKINtnlvNFsKrrk<-*
                   DL  ++++ p ++++ e+     + + ++   +   
   mKIAA0351   232 DLIYIDSAYPasgSIMENE---QRSNQMNNILR    261  

PH: domain 1 of 1, from 412 to 523: score 68.2, E = 1.7e-16
                   *->vikeGwLlkkg........gkkswkkRyfvLfndvLlyykdkk....
                      +++eG L++k+  +++++++++sw ++++vL + +Llyy  k+ +++
   mKIAA0351   412    PTMEGPLRRKTllkegrkpALSSWTRYWVVLSGATLLYYGAKSlrgt 458  

                   ......kkpkgsipLsgiqvekvpdnkrkncFeirt.dr.etlllqaese
                   ++++ +++p +++++ g  v  ++d++++  F++ ++d+++++ +q+ s 
   mKIAA0351   459 drkhykSTPGKKVSIVGWMVQLPDDPEHPDIFQLNNpDKgNVYKFQTGSR 508  

                   eerkeWvkaiqsair<-*
                    ++  W k++ +a++   
   mKIAA0351   509 FHAILWHKHLDDACK    523  

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