hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg19517/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0345  ( 962 res)   mbg19517

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
Cadherin   Cadherin domain                              270.4    2.4e-77   5
Cadherin_2 Cadherin-like                                164.5    1.8e-45   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
Cadherin_2   1/1      46   129 ..     1    84 []   164.5  1.8e-45
Cadherin     1/5     155   250 ..     1   107 []    49.3  8.7e-11
Cadherin     2/5     264   358 ..     1   107 []    80.7    3e-20
Cadherin     3/5     372   463 ..     1   107 []    57.3  3.3e-13
Cadherin     4/5     477   573 ..     1   107 []    60.7  3.1e-14
Cadherin     5/5     585   684 ..     1   107 []    29.0  0.00011

Alignments of top-scoring domains:
Cadherin_2: domain 1 of 1, from 46 to 129: score 164.5, E = 1.8e-45
                   *->gqirYSVpEEterGsfVGNlAKDLGLdvqeLaaRgaRivSggnkqyF
                      gq++YSVpEE+++G+fVG +A+DLGL+++eL  R +R++S+++  ++
   mKIAA0345    46    GQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKDRGDLL 92   

                   qlnletGdLlvnERiDREeLCgqsepCvLhlevllEn<-*
                   ++nl++G L+vn RiDREeLCg+s+ C++hlev+++    
   mKIAA0345    93 EVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDR    129  

Cadherin: domain 1 of 5, from 155 to 250: score 49.3, E = 8.7e-11
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr
                       +  + E  p G++    +A+DaD   g+N+ ++Ys+ + +    F+
   mKIAA0345   155    KNLFIYESRPLGSRFSLEGASDAD--IGTNSLLSYSLNSSE---YFS 196  

                   IdpdtGdnegi....isttkpLDREeifngeYeLtveAtDadpllasggg
                   +d     +e i++ ++ ++k L+RE i  +e++L + A+D+       g 
   mKIAA0345   197 LDV-KRKDEEIkslgLVLKKLLNREDI--PEHNLLITAVDG-------GK 236  

                   pplsstatvtitVl<-*
                   p l++t++v itVl   
   mKIAA0345   237 PELTGTTQVKITVL    250  

Cadherin: domain 2 of 5, from 264 to 358: score 80.7, E = 3e-20
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnp...gg
                      y +++pEnap+Gt v  v A+D D  +g N  i+Ys+ ++ + +   
   mKIAA0345   264    YKVRLPENAPNGTVVVDVDASDLD--EGVNKDIVYSFHQDMSleiLS 308  

                   wFrIdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggp
                   +F++dp +G     i+++ ++D Ee+    +e+ +eA D        g+p
   mKIAA0345   309 KFHLDPISGY----ITVKGNIDFEET--KSFEIQIEAADK-------GTP 345  

                   plsstatvtitVl<-*
                   p+++ +tv +++    
   mKIAA0345   346 PMTDHCTVLVEIV    358  

Cadherin: domain 3 of 5, from 372 to 463: score 57.3, E = 3.3e-13
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr
                       s  v En+++ t ++ + ++D+D  +g+Ng+++ s++++ p +  +
   mKIAA0345   372    LSLPVLENSAPSTVIALISVSDRD--SGANGQVTCSLTPQVPFKLVS 416  

                   IdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggppls
                     ++  +    + +   LDRE+i  + Y+++v A+D+       g+ppl 
   mKIAA0345   417 TFKNYYS----LVLDSVLDRETI--SNYNVVVTARDG-------GSPPLC 453  

                   statvtitVl<-*
                   +ta+v ++V    
   mKIAA0345   454 TTASVSVEVA    463  

Cadherin: domain 4 of 5, from 477 to 573: score 60.7, E = 3.1e-14
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnp.....
                      y++ v+En p+G ++ tv A DaD     N+ ++Ys+++  ++++  
   mKIAA0345   477    YTVFVKENNPPGAHIFTVSAMDAD--AQENALVSYSLVERRVgerll 521  

                   ggwFrIdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgg
                   +   +++ ++G     ++  +pLD Ee   +   + v+A+Da       g
   mKIAA0345   522 SSYVSVHAESGK----VFALQPLDHEEL--ELLQFQVSARDA-------G 558  

                   gpplsstatvtitVl<-*
                    p+l s +t+ + Vl   
   mKIAA0345   559 VPALGSNVTLQVFVL    573  

Cadherin: domain 5 of 5, from 585 to 684: score 29.0, E = 0.00011
                   *->ysa..svpEnap....vGtevltvtAtDaDdPlgpNgrirYsilggn
                      ++a++ v+E ++++ + G  v+ v+A+DaD  +g N+ ++Y + +  
   mKIAA0345   585    PHAgsAVSELVSrtvgAGHVVTKVRAVDAD--SGYNAWLSYELQSAA 629  

                   p..ggwFrIdpdtGdnegiisttkpLDREeif.ngeYeLtveAtDadpll
                    +++  Fr+  +tG+    istt+ LD    +++++ +L v+++D+    
   mKIAA0345   630 GsgRLPFRVGLYTGE----ISTTRVLDE---TdAPRQRLLVLVKDH---- 668  

                   asgggpplsstatvtitVl<-*
                      g+p l++tat+ +++    
   mKIAA0345   669 ---GEPVLTATATLLVSLV    684  

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