hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpg/mpg00583/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0344  ( 800 res)   mpg00583

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       215.6    7.5e-61   1
Pkinase_Tyr Protein tyrosine kinase                      87.3    3.2e-22   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase       1/1     233   491 ..     1   287 []   215.6  7.5e-61
Pkinase_Tyr   1/1     233   491 ..     1   272 []    87.3  3.2e-22

Alignments of top-scoring domains:
Pkinase: domain 1 of 1, from 233 to 491: score 215.6, E = 7.5e-61
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      +++   +G+Gsf tVyk+ +  t  +VA  ++  rk  ++++++   
   mKIAA0344   233    LKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKE 279  

                   rsEiqilkrLsHpNIvrlidvfed....kdhlylVlEycegGLrlldLfd
                     E+++lk L+HpNIvr++d++e++ ++k+ + lV+E++  G     L++
   mKIAA0344   280 --EAEMLKGLQHPNIVRFYDSWEStvkgKKCIVLVTELMTSG----TLKT 323  

                   ylsetrrkgpllfsedeakkialQilrgleYLHsn..giiHRDLKPeNIL
                   yl+   r +++    ++++++++Qil+gl++LH +++ iiHRDLK +NI+
   mKIAA0344   324 YLK---RFKVM--KIKVLRSWCRQILKGLQFLHTRtpPIIHRDLKCDNIF 368  

                   ld.engvvdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggn
                   + + +g v    Ki+D GlA    +++ s ++++ GTp++mAPE     +
   mKIAA0344   369 ITgPTGSV----KIGDLGLAT---LkRASfAKSVIGTPEFMAPEM--YEE 409  

                   gygtkvDvWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefd
                   +y+ +vDv+++G  + e++t + P+s++     +  q++r++ ++  + +
   mKIAA0344   410 KYDESVDVYAFGMCMLEMATSEYPYSEC----QNAAQIYRRVTSGVKPAS 455  

                   spewdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<
                   ++++               +e k++i++c++++  +R++++++l+H +f 
   mKIAA0344   456 FDKVAI-------------PEVKEIIEGCIRQNKDERYSIKDLLNHAFF  491  

                   -*
                     
   mKIAA0344     -    -    

Pkinase_Tyr: domain 1 of 1, from 233 to 491: score 87.3, E = 3.2e-22
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtL.keigasseei
                      lk++ ++G+G+F +VykG       +t+++VA   L+   + + +e 
   mKIAA0344   233    LKFDIEIGRGSFKTVYKGLDT----ETTVEVAWCELqDR-KLTKSE- 273  

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpg.lyiVtEymegG
                    r+ F +EA+++k l +HpNiVr++          g+  + +VtE+m  G
   mKIAA0344   274 -RQRFKEEAEMLKGL-QHPNIVRFYDSWES-TVK-GKKcIVLVTELMTSG 319  

                   dLldfLrkhregrpLtlkdLlsfalQiAkGMeYLeskn..fvHRDLAARN
                    L+++L++    +  ++k L s+++Qi kG+++L+ + ++++HRDL + N
   mKIAA0344   320 TLKTYLKR---FKVMKIKVLRSWCRQILKGLQFLHTRTppIIHRDLKCDN 366  

                   cLVsenl.vVKIsDFGLaRdiynddyYvrkkgggklPv...kWmAPEslk
                   + ++ + + VKI+D GLa +        r++  +k  ++++  mAPE + 
   mKIAA0344   367 IFITGPTgSVKIGDLGLATLK-------RASF-AKSVIgtpEFMAPE-MY 407  

                   ygkFtskSDVWSFGVlLWEiftlGeqPFYpgm.sneevlellyedGyRLp
                   + k+ +  DV++FG ++ E+ t  e P Y +++  ++++ ++  +G   +
   mKIAA0344   408 EEKYDESVDVYAFGMCMLEMAT-SEYP-YSECqNAAQIYRRV-TSGVKPA 454  

                   rPen.CPdelYdlMlqCWaedPedRPtFsel..verL<-*
                     ++ + +e+ +++  C + + ++R + ++l ++ ++   
   mKIAA0344   455 SFDKvAIPEVKEIIEGCIRQNKDERYSIKDLlnHAFF    491  

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