hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj34062/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0327  ( 933 res)   mfj34062

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
Cadherin   Cadherin domain                              277.2    2.2e-79   6
Cadherin_2 Cadherin-like                                186.1    5.7e-52   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
Cadherin     1/6      32   110 ..     1   107 []     8.1     0.22
Cadherin_2   1/1      30   113 ..     1    84 []   186.1  5.7e-52
Cadherin     2/6     139   234 ..     1   107 []    48.1    2e-10
Cadherin     3/6     248   339 ..     1   107 []    76.4    6e-19
Cadherin     4/6     353   444 ..     1   107 []    33.9  3.6e-06
Cadherin     5/6     458   554 ..     1   107 []    67.0  4.1e-16
Cadherin     6/6     576   666 ..     1   107 []    49.4  7.7e-11

Alignments of top-scoring domains:
Cadherin: domain 1 of 6, from 32 to 110: score 8.1, E = 0.22
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr
                         svpE +  Gt v+++      +P+ + +r +   ++g  ++ F+
   mKIAA0327    32    IRYSVPEETDKGTVVGNISKDLGLEPRELAERGVRIVSRGR-SQLFS 77   

                   IdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggppls
                   ++p+ G+    + t+ ++DREe              +          ++s
   mKIAA0327    78 LNPRGGS----LVTAGRIDREEL-------------C----------AQS 100  

                   statvtitVl<-*
                   +++ v+i++l   
   mKIAA0327   101 TPCLVNINIL    110  

Cadherin_2: domain 1 of 1, from 30 to 113: score 186.1, E = 5.7e-52
                   *->gqirYSVpEEterGsfVGNlAKDLGLdvqeLaaRgaRivSggnkqyF
                      gqirYSVpEEt++G++VGN+ KDLGL+++eLa+Rg+RivS+g+ q+F
   mKIAA0327    30    GQIRYSVPEETDKGTVVGNISKDLGLEPRELAERGVRIVSRGRSQLF 76   

                   qlnletGdLlvnERiDREeLCgqsepCvLhlevllEn<-*
                   +ln++ G+L++++RiDREeLC+qs+pC+++ ++l+E    
   mKIAA0327    77 SLNPRGGSLVTAGRIDREELCAQSTPCLVNINILVEE    113  

Cadherin: domain 2 of 6, from 139 to 234: score 48.1, E = 2e-10
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr
                       ++ + E a++G +     A+D+D   g N+  +Y ++++    +F+
   mKIAA0327   139    LEVKINEIAAPGARYPLPEAVDPD--VGINSLQSYQLSPNR---HFS 180  

                   IdpdtGdnegi...isttkpLDREeifngeYeLtveAtDadpllasgggp
                   ++ +tGd+  i++++ + + LDREe   ++++L++ A+D+       g+p
   mKIAA0327   181 LHLQTGDDGTInpeLVLERTLDREEE--PTHHLVLTASDG-------GEP 221  

                   plsstatvtitVl<-*
                    +ssta + itVl   
   mKIAA0327   222 RRSSTALIQITVL    234  

Cadherin: domain 3 of 6, from 248 to 339: score 76.4, E = 6e-19
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnp..ggw
                      y + v En+++Gt +ltv+A+D+D  +g Ng+++Y++ + n++++  
   mKIAA0327   248    YRVKVLENVAPGTLLLTVRASDPD--EGVNGKVTYKFRKINEkqSLL 292  

                   FrIdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggpp
                   F+++++tG+     +++k+LD+Ee+  + Ye  + A D +         +
   mKIAA0327   293 FHLHENTGE----MTVAKNLDYEEC--SLYEMEIQAEDVG---------A 327  

                   lsstatvtitVl<-*
                   l ++  v+i V+   
   mKIAA0327   328 LLGRSKVIIMVE    339  

Cadherin: domain 4 of 6, from 353 to 444: score 33.9, E = 3.6e-06
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr
                          v En+ +Gt ++ ++++D D  +g Ng+++     ++ +  F+
   mKIAA0327   353    LFNPVLENSLPGTVIAFLNVHDQD--SGKNGQVVCY--THD-NLPFK 394  

                   IdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggppls
                   +++ + dn   + t k LDRE+   ++Y++tv+A+D        g ppls
   mKIAA0327   395 LEK-SIDNYYRLVTWKYLDREKV--STYNITVIASDL-------GAPPLS 434  

                   statvtitVl<-*
                   +++++  tV    
   mKIAA0327   435 TETYIALTVA    444  

Cadherin: domain 5 of 6, from 458 to 554: score 67.0, E = 4.1e-16
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnp.....
                      y+a +pEn  +G ++ ++tA+D+D  +  N++++Ys +++  ++ + 
   mKIAA0327   458    YTAYLPENNLRGASIFSLTAHDPD--SQENAQVTYSVSEDTIqgvpl 502  

                   ggwFrIdpdtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgg
                   +   +I++dtG     ++  ++ D E+i  +   L v+AtD+       g
   mKIAA0327   503 SSYISINSDTGI----LYALQSFDFEKI--QDLQLLVIATDS-------G 539  

                   gpplsstatvtitVl<-*
                   +pplss +++   Vl   
   mKIAA0327   540 SPPLSSNVSLSLFVL    554  

Cadherin: domain 6 of 6, from 576 to 666: score 49.4, E = 7.7e-11
                   *->ysasvpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnpggwFr
                       +   +  +p G  v+ v A+D+D  +g+N+ ++Y++l+ +++g F+
   mKIAA0327   576    VELAPRSAEP-GYLVTKVVAVDKD--SGQNAWLSYRLLKASEPGLFS 619  

                   IdpdtGdnegiisttkp.LDREeifngeYeLtveAtDadpllasgggppl
                   +  +tG+    ++t++  LDR +    + +L++ ++D+       g+ppl
   mKIAA0327   620 VGLHTGE----VRTARAlLDRDAL--KQ-NLVMAVQDH-------GQPPL 655  

                   sstatvtitVl<-*
                   s+t+t+t+ V    
   mKIAA0327   656 SATVTLTVAVA    666  

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