hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg14966/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0318  ( 884 res)   mbg14966

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
SH3      Src homology 3 domains                         157.0    1.9e-42   3
FN3      Fibronectin type 3 domain                       65.7    5.8e-15   3

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
SH3        1/3       1    59 [.     1    58 []    32.6  5.3e-05
FN3        1/3     123   203 ..     1    69 []    19.9     0.36
FN3        2/3     217   289 ..     1    69 []    25.4   0.0081
FN3        3/3     313   399 ..     1    69 []    22.2    0.074
SH3        2/3     683   747 ..     1    58 []    51.8  8.8e-11
SH3        3/3     787   850 ..     1    58 []    74.6  1.2e-17

Alignments of top-scoring domains:
SH3: domain 1 of 3, from 1 to 59: score 32.6, E = 5.3e-05
                   *->eyvvAlYDyea......qnedELsFkkGDiitvleks.ddgWweGel
                            Y+y++ +++++  e EL++++G  ++v  + ++dg +eGel
   mKIAA0318     1    -----RYSYNPfdgpneNPEAELPLTAGKYLYVYGDMdEDGFYEGEL 42   

                   nrtGkeGlfPsnYVeeie<-*
                     +G++Gl+Psn+V  i+   
   mKIAA0318    43 L-DGQRGLVPSNFVDFIQ    59   

FN3: domain 1 of 3, from 123 to 203: score 19.9, E = 0.36
                   *->PgpPsnptelrvtdvtststsdltsvtlsWepP........ivgYr.
                       + P+    +++    +       sv + WepP  +++ + + +Y +
   mKIAA0318   123    VPYPRK---ITLIKQLAK------SVIVGWEPPavppgwgtVSSYNv 160  

                   .................ytltgLkPgaepwteYefrVrAvngndaGeg<-
                    ++++++ +   ++++++ ++ L   a    +Y+++V++v++  +G +  
   mKIAA0318   161 lvdketrmslalgrrtkALIEKLNTAA---CTYRISVQCVTS--RGNS   203  

                   *
                    
   mKIAA0318     -   -    

FN3: domain 2 of 3, from 217 to 289: score 25.4, E = 0.0081
                   *->PgpPsnptelrvtdvtststsdltsvtlsWepP......ivgYr...
                        +Ps    lrv ++t        s++lsW p ++++++i+   +++
   mKIAA0318   217    VVAPSQ---LRVDNITQI------SAQLSWLPTnsnyshIIFLNeee 254  

                   ..........ytltgLkPgaepwteYefrVrAvngndaGeg<-*
                    + ++  + +y + +L+P+      Y+++V A  +  + +    
   mKIAA0318   255 ldivkaarykYQFFNLRPN----MAYKVKVLAQPH--QMPW    289  

FN3: domain 3 of 3, from 313 to 399: score 22.2, E = 0.074
                   *->PgpPsnptelrvtdvtststsdltsvtlsWepP............iv
                      P pP++   ++v++  +      +sv++sW+pP   + + +++ +++
   mKIAA0318   313    PAPPQD---VTVHAGATA-----ASVQVSWKPPaltptglsnganVT 351  

                   gYr....................ytltgLkPgaepwteYefrVrAvngnd
                   gY +  +++++ ++  ++ +++ + l  L+          ++Vr  +   
   mKIAA0318   352 GYGvyakgqrvaeviaptadgtaVELIRLRSL----EAKAVSVRTLSV-- 395  

                   aGeg<-*
                   +Ge+   
   mKIAA0318   396 QGES    399  

SH3: domain 2 of 3, from 683 to 747: score 51.8, E = 8.8e-11
                   *->eyvvAlYDyea........qnedELsFkkGDiitvleks.ddgWweG
                      + +vAl+Dy++ + +++++  e+EL+Fk+G+ii v  + + dg ++G
   mKIAA0318   683    RIFVALFDYDPltmspnpdAAEEELPFKEGQIIKVYGDKdADGFYRG 729  

                   elnrtGkeGlfPsnYVeeie<-*
                   e +   + Gl+P+n V ei+   
   mKIAA0318   730 ETC--ARLGLIPCNMVSEIH    747  

SH3: domain 3 of 3, from 787 to 850: score 74.6, E = 1.2e-17
                   *->eyvvAlYDyea.......qnedELsFkkGDiitvleks.ddgWweGe
                      +++vAlYDy++++++++ + e EL+F  GDiitv  ++++dg ++Ge
   mKIAA0318   787    RRMVALYDYDPresspnvDVEAELPFCTGDIITVFGEIdEDGFYYGE 833  

                   lnrtGkeGlfPsnYVeeie<-*
                   ln  G++Gl+Psn++ee++   
   mKIAA0318   834 LN--GQKGLVPSNFLEEVP    850  

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