hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg01653/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0317  ( 826 res)   mbg01653

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
HECT     HECT-domain (ubiquitin-transferase)            434.6     9e-127   1
Filamin  Filamin/ABP280 repeat                          -18.0      0.046   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Filamin    1/1      57   158 ..     1   101 []   -18.0    0.046
HECT       1/1     515   826 .]     1   366 []   434.6   9e-127

Alignments of top-scoring domains:
Filamin: domain 1 of 1, from 57 to 158: score -18.0, E = 0.046
                   *->agDasKVkAyGPGLeggGVkvgkPaeFtVdtVdkdGepkgAGgG...
                       +D+  +k++     +   +vg +  F V+         ++G+  + 
   mKIAA0317    57    YLDPRSCKVSWDWKDPY--EVGHSMAFRVHL------FYKNGQPfpa 95   

                   ...........gLsVkVeGPsGaeAvvevkvtDngDGtYtVsYtPtepGd
                   +++ + + + ++++++V  P  +    ev  + n +    V++t +++G 
   mKIAA0317    96 hrpvglrvhisHVELAVDIPVTQ----EVLQEPNSNV-VKVAFTVRKAGR 140  

                   YtvnVtygGehIPgSPFk<-*
                   Y+++V++gG +++ SP+    
   mKIAA0317   141 YEITVKLGGLNVAYSPYY    158  

HECT: domain 1 of 1, from 515 to 826: score 434.6, E = 9e-127
                   *->tLlsrelfnPdygLFeysdnseakseeddsysgyvedsytlfpnPls
                       L++++lf++   LF +                  +ds++  ++P++
   mKIAA0317   515    ELICKALFDTTSQLFAR-----------------FTDSNQALVHPNP 544  

                   gesnpehervlkyFkflGrilGlAlyd.......grllDlpFsraFyKkl
                     +++++   lk+++f Gr++G++ly+++ ++   +l+ ++F+r+F+ ++
   mKIAA0317   545 NRPAHLR---LKMYEFAGRLVGKCLYEsslggayKQLVRARFTRSFLAQI 591  

                   LmagkpsigivtleDlesvDPelynS.LkwllendgdKkIedsLLgsled
                   +  g++    ++++ +e  DPe+y+S+ + +l+nd +             
   mKIAA0317   592 I--GLR----MHYKYFETDDPEFYKSkVCFILNNDMS------------- 622  

                   veedLeLtFsveeessv.g.feadarffGgtktveELkPnGrnipVTneN
                      ++eL F +ee  +++g++          k ve L  +G+++pVTn+N
   mKIAA0317   623 ---EMELVF-AEEKYNKsGqL---------DKIVE-LMTGGAQTPVTNAN 658  

                   keeYvelyvdyrLnkgiekQfeAFrkGFsevipsrlLslFdpeELelLic
                   k+ Y++l+++yrL  ++++ +e+F+kG++e++p++lL++Fd++ELelL+c
   mKIAA0317   659 KIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMC 708  

                   GspeeiDvddLkenTeYdggYtedsplktiqwFWevleeftneeraklLq
                   G + +i+v+d+k++++  gg+++  + k+ +wFW v++++t+ee a+lLq
   mKIAA0317   709 GTG-DINVSDFKAHAVVVGGSWHFRE-KVMRWFWAVVSSLTQEELARLLQ 756  

                   FvTGssRlPvgGFkaLqgGsnGpPkFtIvrkegggdddrLPtAhTCFNrL
                   F+TGss+lP+gGF+aL       P+F+I  +   ++++ LPtAhTCFN+L
   mKIAA0317   757 FTTGSSQLPPGGFAALC------PSFQIIAA---PTHSTLPTAHTCFNQL 797  

                   kLPpYsSkeiLrekLllAInEgseGFgle<-*
                   +LP Y S+e  +++L lAI+Eg+eGFg++   
   mKIAA0317   798 CLPTYDSYEEVHRMLQLAISEGCEGFGML    826  

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