hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg03233/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0313  ( 1138 res)   mbg03233

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RasGEF   Guanine nucleotide exchange factor for Ras-l   347.2    1.1e-99   1
RA       Ras association (RalGDS/AF-6) domain            91.0    1.4e-22   1
PDZ      Domain present in PSD-95, Dlg, and ZO-1/2.      56.6    3.2e-12   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PDZ        1/1      37   109 ..     1    80 []    56.6  3.2e-12
RA         1/1     248   334 ..     1   102 []    91.0  1.4e-22
RasGEF     1/1     355   592 ..     1   261 []   347.2  1.1e-99

Alignments of top-scoring domains:
PDZ: domain 1 of 1, from 37 to 109: score 56.6, E = 3.2e-12
                   *->gglGfsivg......gifvssvvpGspAakaGrkslglLkvGDvIle
                      ++l f + g+++++ gifv sv   s A  aG      Lk GD+Ile
   mKIAA0313    37    APLPFILLGgsekgfGIFVDSVDSCSKATEAG------LKRGDQILE 77   

                   VNGetsvegltheeavdllkkaggggvGekvtLtvlRgg<-*
                   VNG ++ e+     a+++l++      ++++++tv+ +    
   mKIAA0313    78 VNG-QNFENIQLSKAMEILRN------NTHLSITVKTNL    109  

RA: domain 1 of 1, from 248 to 334: score 91.0, E = 1.4e-22
                   *->dtyvlrVyvddlsavdpgqtyktlrvskrtTardViqqllekfhltd
                        +vlrV+ +d       q+++++++sk+tTa++V+ q++++f +t+
   mKIAA0313   248    PDQVLRVFKAD-------QQSRYIMISKDTTAKEVVIQAIREFAVTA 287  

                   edpeeYvLvevlpsggkErvLlddenPlqlqklwprdaksprqsslrFvL
                    +pe+Y+L+ev+  +  E v++++++P ql kl+ r+     q s r++L
   mKIAA0313   288 -TPEQYSLCEVS--VTPEGVIKQRRLPDQLSKLADRI-----QLSGRYYL 329  

                   rkrdd<-*
                   ++++    
   mKIAA0313   330 KNNME    334  

RasGEF: domain 1 of 1, from 355 to 592: score 347.2, E = 1.1e-99
                   *->lllldpeelAeQLTlldfelFrkIepsEllgsvwgkrskkspsplap
                      ll+l+++e+A+QL+++ felFr+Iep+E+++ +++ +sk s++    
   mKIAA0313   355    LLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLKSKTSCA---- 397  

                   qnleafierfNevsnwVateIlkqttlkpkkRaevlskFIkVAkhcreLn
                    nl++f e+ N+ ++wVa+eIl++t+    kR++++++FIk+A hcre++
   mKIAA0313   398 -NLKKFEEVINQETFWVASEILRETN--QLKRMKIIKHFIKIALHCRECK 444  

                   NFnSlmAIvsaLssspIsRLkkTWeklsskykklfeeLeelldpserNfk
                   NFnS++AI+s+L+ +p+ RL+ TWekl++ky+klf++L++l+dps rN+ 
   mKIAA0313   445 NFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDLQDLFDPS-RNMA 493  

                   nYReaLkscnkspnvqppcvPflGvyLkDLtfidegnpdflengtkglvN
                   +YR++L+  n+    qpp++P ++v+ kDLtf++egn+  ++    glvN
   mKIAA0313   494 KYRNVLSGQNL----QPPVIPLFPVIKKDLTFLHEGNDSKVD----GLVN 535  

                   FeKrrkiakilreirqlqsacqpynlkpnrndiqellrasrplevlpeee
                   FeK+r+iak +r++ +++s  ++++++ ++++ ++ +r+   l++l++  
   mKIAA0313   536 FEKLRMIAKEIRHVGRMAS--VNMDPALMFRTRKKKWRS---LGSLSQG- 579  

                   delyelSlriEPrv<-*
                      ++  l +   +   
   mKIAA0313   580 -SANATVLDVAQTG    592  

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