hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg03233/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0313  ( 1138 res)   mbg03233

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RasGEF   RasGEF domain                                  198.7    9.1e-56   1
RA       Ras association (RalGDS/AF-6) domain            76.2    6.9e-19   1
PDZ      PDZ domain (Also known as DHR or GLGF)          44.0    3.3e-09   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PDZ        1/1      29   106 ..     1    82 []    44.0  3.3e-09
RA         1/1     248   334 ..     1    98 []    76.2  6.9e-19
RasGEF     1/1     356   541 ..     1   227 []   198.7  9.1e-56

Alignments of top-scoring domains:
PDZ: domain 1 of 1, from 29 to 106: score 44.0, E = 3.3e-09
                   *->evtlekevkrgglGfsikggsdk..givvsevlpGsgaAeagGrLke
                      ++t++      +l f + ggs+k+ gi+v +v   s a eag  Lk 
   mKIAA0313    29    TLTKPS--REAPLPFILLGGSEKgfGIFVDSVDSCSKATEAG--LKR 71   

                   GDqIlsvNGqdvenlsheravlalkgsggsevtLtil<-*
                   GDqIl+vNGq++en+++ +a+++l++    ++++t++   
   mKIAA0313    72 GDQILEVNGQNFENIQLSKAMEILRNNT--HLSITVK    106  

RA: domain 1 of 1, from 248 to 334: score 76.2, E = 6.9e-19
                   *->dsgvlrVygedgtpgtyktilvskntTaeeViralLrKfgldaddpe
                       + vlrV++ d++   ++ i++sk+tTa+eV+ ++ r f + + +pe
   mKIAA0313   248    PDQVLRVFKADQQ---SRYIMISKDTTAKEVVIQAIREFAV-TATPE 290  

                   dyvLvEvslvlerggeerrvLpddEkPlqiqlqlkrdaqvrsrFlLrrre
                    y+L+Evs+  e  +++r +Lpd+   l  + ql      ++r++L+++ 
   mKIAA0313   291 QYSLCEVSVTPEGVIKQR-RLPDQLSKLADRIQL------SGRYYLKNNM 333  

                   d<-*
                   +   
   mKIAA0313   334 E    334  

RasGEF: domain 1 of 1, from 356 to 541: score 198.7, E = 9.1e-56
                   *->LllDplelAkQLTLlEhelfkkItpfefLgsKmKHEGPqvWgkksfk
                      L l+ +e+A+QL  +++elf++I+p e  +         + + k   
   mKIAA0313   356    LQLSTVEVATQLSMRNFELFRNIEPTEYID--------DLFKLK--- 391  

                   gkeerspnidktiknfNqltnfvsetIlkqeFPTNPEFSKkvdpkkRaev
                    +  +  n+ k+    Nq t +v+++Il+++           +  kR+++
   mKIAA0313   392 -SKTSCANLKKFEEVINQETFWVASEILRET-----------NQLKRMKI 429  

                   iqkfIqVAdhcReLnNFnSllaIisALysspIyRLkkTWekvppqslklI
                   i++fI +A hcRe +NFnS++aIis+L+ +p+ RL+ TWek+p ++ kl 
   mKIAA0313   430 IKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKL- 478  

                   feeLnkLmdsdrNfsnyRelLksigplappnLdddfvraPCVPFfGvYLs
                   f++L+ L+d++rN  +yR++L+  +            + P++P f+v+ +
   mKIAA0313   479 FQDLQDLFDPSRNMAKYRNVLSGQNL-----------QPPVIPLFPVIKK 517  

                   DLtfleeGnpdyleekKINtnlvNFsKrrk<-*
                   DLtfl+eGn+++        +lvNF+K r+   
   mKIAA0313   518 DLTFLHEGNDSKVD------GLVNFEKLRM    541  

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