hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file: /cdna4/rodent/full/goal/mbg/mbg05848/w3open/interpro/cnk_1/seq.in
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Query: mKIAA0302 ( 1972 res) mbg05848
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Spectrin Spectrin repeat 1135.9 0 16
PH PH domain 59.6 6.8e-14 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Spectrin 1/16 9 113 .. 1 108 [] 95.9 8.2e-25
Spectrin 2/16 115 223 .. 1 108 [] 91.9 1.3e-23
Spectrin 3/16 225 329 .. 1 108 [] 73.2 5.3e-18
Spectrin 4/16 331 434 .. 1 108 [] 86.6 5.1e-22
Spectrin 5/16 436 540 .. 1 108 [] 84.2 2.6e-21
Spectrin 6/16 542 647 .. 1 108 [] 95.7 9e-25
Spectrin 7/16 649 754 .. 1 108 [] 74.9 1.7e-18
Spectrin 8/16 756 860 .. 1 108 [] 63.6 4.3e-15
Spectrin 9/16 862 965 .. 1 108 [] 85.6 9.8e-22
Spectrin 10/16 967 1070 .. 1 108 [] 90.7 2.9e-23
Spectrin 11/16 1072 1170 .. 1 108 [] 70.7 3e-17
Spectrin 12/16 1172 1276 .. 1 108 [] 92.9 6.4e-24
Spectrin 13/16 1278 1383 .. 1 108 [] 91.4 1.8e-23
Spectrin 14/16 1385 1489 .. 1 108 [] 74.9 1.7e-18
Spectrin 15/16 1491 1595 .. 1 108 [] 68.0 2e-16
Spectrin 16/16 1597 1684 .. 1 108 [] 12.9 0.064
PH 1/1 1803 1912 .. 1 92 [] 59.6 6.8e-14
Alignments of top-scoring domains:
Spectrin: domain 1 of 16, from 9 to 113: score 95.9, E = 8.2e-25
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
+l +F r+a+ e W+se ++l+s++++g +l++v+a ++kHea+e
mKIAA0302 9 QLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIE 55
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
+++ a+ +rv+++++ a +L +e+ ++d ++i +r++ + ++W+ L++
mKIAA0302 56 TDIVAYS-GRVQAVDAVAAELAAEH--YHDIKRIAARQNNVARLWDFLRQ 102
laaeRkqkLee<-*
++a+R+++L+
mKIAA0302 103 MVAARRERLLL 113
Spectrin: domain 2 of 16, from 115 to 223: score 91.9, E = 1.3e-23
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
l+lq+ ++d+ l+ W+ e++ l+s+d+gk+l++v++Ll+ He e
mKIAA0302 115 LELQKVFQDLLYLMDWMAEMKGRLQSQDLGKHLAGVEDLLQLHELVE 161
aelaahqqdrvdqlnelaqkLieeged..hpdseeikerleeLnerWeaL
a++a++ +rv+++ + a ++ + g + +++d + er++ L++ +eaL
mKIAA0302 162 ADIAVQA-ERVRAVSASALRFCDPGKEyrPCDPQLVSERVATLEQSYEAL 210
lelaaeRkqkLee<-*
+elaa+R+++Lee
mKIAA0302 211 CELAATRRARLEE 223
Spectrin: domain 3 of 16, from 225 to 329: score 73.2, E = 5.3e-18
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
+l++F +++ e+e+W +e++ ll+s d g+Dl++v +Ll kH a++
mKIAA0302 225 RRLWRFLWEVGEAEAWVREQQHLLASADTGRDLTGVLRLLNKHAALR 271
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
e+ ++ + ++ e++q+L++eg hp + + +r +eL ++We+L++
mKIAA0302 272 GEMSGRL-GPLKLTLEQGQQLVAEG--HPGANQASTRAAELQAQWERLEA 318
laaeRkqkLee<-*
la+eR q+L +
mKIAA0302 319 LAEERAQQLAQ 329
Spectrin: domain 4 of 16, from 331 to 434: score 86.6, E = 5.1e-22
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
l+qFq da+++e+W+ ++ +l+ss + g+D+ s+qaL ++H+a+e
mKIAA0302 331 ASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQHRALE 377
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
+e+ ah+ + +d+l e+a +L + ++e++ r+ L++++e+L++
mKIAA0302 378 EEIRAHR-PTLDALREQAAALPPAL---SHTPEVQGRVPTLEQHYEELQT 423
laaeRkqkLee<-*
+a eR ++Le+
mKIAA0302 424 RAGERARALEA 434
Spectrin: domain 5 of 16, from 436 to 540: score 84.2, E = 2.6e-21
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
l ++ + +a + +W +eke++l+ +++ le+++ ++++e++e
mKIAA0302 436 LAFYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLE 482
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
e++a+ +rv ++n++a++L+ ++ +p +++i ++e+Ln+rW++ +
mKIAA0302 483 PEMNALA-ARVTAVNDIAEQLLKAS--PPGKDRIIGTQEQLNQRWQQFRS 529
laaeRkqkLee<-*
la+ +k++L
mKIAA0302 530 LADGKKAALTS 540
Spectrin: domain 6 of 16, from 542 to 647: score 95.7, E = 9e-25
*->lllqqFqrdadelesWisekeallssedygk.DlesvqaLlkkHeaf
l +q ++ ++ e ++W++ek + ++s++ ++Dl++v aL++k+ +
mKIAA0302 542 LSIQNYHLECTETQAWMREKTKVIESTQGLGnDLAGVLALQRKLAGT 588
eaelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLl
e++l+a+ +rv +l+++a++L + + + ++++i +rl e+ + We+L+
mKIAA0302 589 ERDLEAIS-ARVGELTQEANALAAGH--PAQAPAINTRLGEVQAGWEDLR 635
elaaeRkqkLee<-*
+ + +R++ L e
mKIAA0302 636 ATMRRREESLGE 647
Spectrin: domain 7 of 16, from 649 to 754: score 74.9, E = 1.7e-18
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
+lq F r +d++++W++ +++ ++se+ + +l +++aLl +H a++
mKIAA0302 649 RRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLAQHAALR 695
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
e++ q + + l l+++++ +++d p+ +++rle+L + We+L +
mKIAA0302 696 GEVERAQ-SEYSRLRTLGEEVTRDQAD-PQCLFLRQRLEALGTGWEELGR 743
laaeRkqkLee<-*
+++ R+ +L +
mKIAA0302 744 MWESRQGRLAQ 754
Spectrin: domain 8 of 16, from 756 to 860: score 63.6, E = 4.3e-15
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
+ +q F rda+++e +s +e ls ++++++l+++ a +kk+e+f+
mKIAA0302 756 HGFQGFLRDARQAEGVLSSQEYVLSHTEMPGTLQAADAAIKKLEDFM 802
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
++a++ +r+++l e +++L+++g +e+i+e+ + +++r ++ +e
mKIAA0302 803 STMDANG-ERIRGLLEAGRQLVSKG--NIHAEKIQEKADSIEKRHRKNQE 849
laaeRkqkLee<-*
++++ +L++
mKIAA0302 850 AVQQLLGRLRD 860
Spectrin: domain 9 of 16, from 862 to 965: score 85.6, E = 9.8e-22
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
++q F +d++el++Wi+ek+ ++++ +y + ++ +++kH+af+
mKIAA0302 862 REQQHFLQDCQELKLWIDEKMLTAQDVSYD-EARNLHTKWQKHQAFM 907
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
aelaa++ d++d +++++++L+ e+ ++ + + e+le+L++rW++L++
mKIAA0302 908 AELAANK-DWLDKVDKEGRELTLEK--PELKVVVSEKLEDLHRRWDELET 954
laaeRkqkLee<-*
++++ + L +
mKIAA0302 955 TTQAKARSLFD 965
Spectrin: domain 10 of 16, from 967 to 1070: score 90.7, E = 2.9e-23
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
++ ++F++ ++ lesW++ +a+l s+dygkDl+sv Llkk++ +e
mKIAA0302 967 NRAELFAQSCSALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLE 1013
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
+e+a+++ +v++++++aq+L +e +++ e++ + +++e+++aL++
mKIAA0302 1014 REMAVRE-KEVEAIQAQAQALAQE---DQSAGEVERTSRAVEEKFRALCQ 1059
laaeRkqkLee<-*
++eR ++L++
mKIAA0302 1060 PMKERCRRLHA 1070
Spectrin: domain 11 of 16, from 1072 to 1170: score 70.7, E = 3e-17
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
+++qF+rd++++ +W +e +++ss ++gkDl svq L+kk ++++
mKIAA0302 1072 REQHQFHRDVEDEILWVTERLPMASSLEHGKDLPSVQLLMKKNQTLQ 1118
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
+e+++h+ +r+ +l e + L ++ + l+eL e W++L
mKIAA0302 1119 KEIQGHE-PRIADLKERQRTLGTAAAG--------PELAELQEMWKRLSH 1159
laaeRkqkLee<-*
++ R ++Lee
mKIAA0302 1160 ELELRGKRLEE 1170
Spectrin: domain 12 of 16, from 1172 to 1276: score 92.9, E = 6.4e-24
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
l+ qqF+rda+e+e+W++e+e ++++kD+ s+qa +kkH+ +e
mKIAA0302 1172 LRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQAEVKKHQVLE 1218
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
+ la + ++ql + q++i+ hp+s +++ r++++++++++L+e
mKIAA0302 1219 QALADYA-QTIKQLAASSQDMIDHE--HPESTRLTIRQAQVDKLYASLKE 1265
laaeRkqkLee<-*
la eR+++L+e
mKIAA0302 1266 LAGERRERLQE 1276
Spectrin: domain 13 of 16, from 1278 to 1383: score 91.4, E = 1.8e-23
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
l+l q+ r++d+le+Wi+e e ++s ++g+D e+v L +k+++f
mKIAA0302 1278 LRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFS 1324
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
++ +++q+rvd+ n+la+ Li+ g h + + e+++ Lne+W++Lle
mKIAA0302 1325 KDTSTIGQERVDSANALANGLIAGG--HAARATVAEWKDSLNEAWADLLE 1372
laaeRkqkLee<-*
l+++R q L +
mKIAA0302 1373 LLDTRGQVLAA 1383
Spectrin: domain 14 of 16, from 1385 to 1489: score 74.9, E = 1.7e-18
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
++lq+F + a+++++ + k+++l + g+Dl +++aL+++H a+e
mKIAA0302 1385 YELQRFLHGARQALARVQHKQQQLPDG-TGRDLNAAEALQRRHCAYE 1430
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
++++a+ ++v+q+++ +q+L+ +++ ++ +eei ++++ e+W++L+
mKIAA0302 1431 HDIQALS-TQVQQVQDDGQRLQKAYA-GDKAEEIGRHMQAVAEAWAQLQG 1478
laaeRkqkLee<-*
a+R+q+L++
mKIAA0302 1479 SSAARRQLLLD 1489
Spectrin: domain 15 of 16, from 1491 to 1595: score 68.0, E = 2e-16
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
+ ++F++ ++el++W++ + + ++ ++D++s+ +k +++++
mKIAA0302 1491 TDKFRFFKAVRELMLWMDGINLQMDAQERPRDVSSADLVIKNQQGIK 1537
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
ae++a+ dr++++ +++q+L++++ h+++eei e+l++L +r+++ +
mKIAA0302 1538 AEIEARA-DRFSSCIDMGQELLARS--HYAAEEISEKLSQLQSRRQETAD 1584
laaeRkqkLee<-*
+++e+ +L+
mKIAA0302 1585 KWQEKMDWLQL 1595
Spectrin: domain 16 of 16, from 1597 to 1684: score 12.9, E = 0.064
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeafe
l+ F rda +e+W+ +e+l++s ++g ++++v++L+k+Heaf+
mKIAA0302 1597 LEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQ 1643
aelaahqqdrvdqlnelaqkLieegedhpdseeikerleeLnerWeaLle
+ a++ +r+++l +kL++ ++e+ ++r ee
mKIAA0302 1644 KSAVAWE-ERFSAL----EKLTALE--ERENERKRKREEE---------- 1676
laaeRkqkLee<-*
eR+++
mKIAA0302 1677 ---ERRKQPPT 1684
PH: domain 1 of 1, from 1803 to 1912: score 59.6, E = 6.8e-14
*->vikeGwLlkkg.........gkkswkkRyfvLfndvLlyykdkk...
+eG L +k + + +++ +++sw+ +y+vL++++L +ykd +
mKIAA0302 1803 EQMEGMLCRKQemeafnkkaANRSWQNVYCVLRRGSLGFYKDARaas 1849
..kkpkgsipLsgiqvekvpdn...krkncFeirt.dretlllqaeseee
+ + g +p+s ++ ++ + +krk++F++ +d++++l+qa++e e
mKIAA0302 1850 agVPYHGEVPVSLARAQGSVAFdyrKRKHVFKLGLqDGKEYLFQAKDEAE 1899
rkeWvkaiqsair<-*
+ +W++ + ai+
mKIAA0302 1900 MSSWLRVVNAAIA 1912
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