hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh04731/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0282  ( 831 res)   mbh04731

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N 
--------        -----------                             -----    ------- ---
SPRY            SPRY domain                              49.3    8.6e-11   1
fn3             Fibronectin type III domain              39.1      1e-07   1
zf-B_box        B-box zinc finger                        28.2    0.00019   2
zf-C3HC4        Zinc finger, C3HC4 type (RING finger)    16.5       0.02   1
TFIIB_Zn_Ribbon TFIIB zinc-binding                        8.6       0.15   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
TFIIB_Zn_Ribbon   1/1      51    90 ..     1    43 []     8.6     0.15
zf-C3HC4          1/1      53    90 ..     1    50 []    16.5     0.02
zf-B_box          1/2     208   255 ..     1    46 []     3.7     0.31
zf-B_box          2/2     269   309 ..     1    46 []    33.3  5.7e-06
fn3               1/1     482   568 ..     1    84 []    39.1    1e-07
SPRY              1/1     715   819 ..     1   154 []    49.3  8.6e-11

Alignments of top-scoring domains:
TFIIB_Zn_Ribbon: domain 1 of 1, from 51 to 90: score 8.6, E = 0.15
                   *->mkCPeCGs...teiveDyerGelvCtdCGlVieeniIDsgpEWraf<
                      +kCP CGs  ++ i+   +++   C +C      ni ++ pE +   
   mKIAA0282    51    LKCPVCGSfyrEPIILPCSHN--LCQACAR----NILVQTPESESP  90   

                   -*
                     
   mKIAA0282     -    -    

zf-C3HC4: domain 1 of 1, from 53 to 90: score 16.5, E = 0.02
                   *->CrICleelkepsndfplilpCgHsGslkyfCrsClerwlss...sgn
                      C++C   + ep      ilpC H       C++C ++ l ++++s++
   mKIAA0282    53    CPVCGSFYREPI-----ILPCSHN-----LCQACARNILVQtpeSES 89   

                   ttCplC<-*
                            
   mKIAA0282    90 P-----    90   

zf-B_box: domain 1 of 2, from 208 to 255: score 3.7, E = 0.31
                   *->ervCpeHg...ekaslfCedDqalLCvvCdesgeHsanklargHtvv
                      + +C+ +++ +++a++ Ce+++ + C  C++   H   +  ++H+ v
   mKIAA0282   208    ALKCQLCEkapKEATVMCEQCDVFYCDPCRLR-CHPPRGPLAKHRLV 253  

                   pl<-*
                   p    
   mKIAA0282   254 PP    255  

zf-B_box: domain 2 of 2, from 269 to 309: score 33.3, E = 5.7e-06
                   *->ervCpeHg.ekaslfCedDqalLCvvCdesgeHsanklargHtvvpl
                         C+ H+ e  s++C+++ ++ C +C e g+H      + H v+ l
   mKIAA0282   269    VSTCTDHElENHSMYCVQCKMPVCYQCLEEGKH------SSHEVKAL 309  

                   <-*
                      
   mKIAA0282     -     -    

fn3: domain 1 of 1, from 482 to 568: score 39.1, E = 1e-07
                   *->P.saPtnltvtdv..tstsltlsWsppt.gngpitgYevtyRqpkng
                      P +a   l+ ++  + ++s+tlsW+ p+      +gY +++  + +g
   mKIAA0282   482    PvPATPILQLEECctHNNSATLSWKQPPlSTVAADGYILEL-DDGSG 527  

                   gewneltvpgtttsytltgLkPgteYevrVqAvnggG.GpeS<-*
                   g+ +e+ v + t  +t+ gL  +++Y+ rV+A n  G +p+S   
   mKIAA0282   528 GQFREVYVGKET-MCTVDGLHFNSTYNARVKAFNKTGvSPYS    568  

SPRY: domain 1 of 1, from 715 to 819: score 49.3, E = 8.6e-11
                   *->sGkhYfEVevdtgggepthwrvGwatksvhlppgfdlrsskrkgger
                      +G+hY+E ++d ++    + ++G+a+ +v               ++ 
   mKIAA0282   715    KGVHYWELTIDRYDN-HPDPAFGVARIDV--------------MKDM 746  

                   llGddegswgydgsggkkyhagesgepyglpfqekgdviGcflDyeagVt
                   +lG+d++ w++       + +g +          kg +iG++lD+    t
   mKIAA0282   747 MLGKDDKAWAI-------TEGGIT----------KGATIGVLLDLNRK-T 778  

                   isFtkNGkyLgdsEshiyaFrnvtfdkkpggpLyPavslgsadgggeair
                   ++F++N ++ g       aF+nv++       ++Pavsl+     +++ +
   mKIAA0282   779 LTFFVNNEQQGP-----IAFENVEGL------FFPAVSLN-----RNVQV 812  

                   lnfgqlp<-*
                   +   +lp   
   mKIAA0282   813 TLHTGLP    819  

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