hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs Sequence file: /cdna4/rodent/full/goal/meh/meh01738/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA0279 ( 1484 res) meh01738 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- LamG Laminin G domain 207.3 1.4e-57 2 GPS G-protein-coupled receptor proteolytic site 99.8 3.1e-25 1 EGF Epidermal growth factor-like domain. 95.6 5.8e-24 8 HormR Domain present in hormone receptors 83.4 2.7e-20 1 EGF_CA Calcium-binding EGF-like domain 77.1 2.2e-18 5 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- EGF 1/8 26 81 .. 1 32 [] 27.1 0.0024 EGF 2/8 86 119 .. 1 32 [] 31.1 0.00015 EGF_CA 1/5 83 119 .. 1 34 [] 43.4 3.1e-08 EGF_CA 2/5 127 161 .. 1 34 [] 21.1 0.004 EGF 3/8 126 161 .. 1 32 [] 21.9 0.09 LamG 1/2 182 349 .. 1 137 [] 114.2 1.5e-29 EGF 4/8 372 405 .. 1 32 [] 31.6 0.0001 EGF_CA 3/5 373 405 .. 1 34 [] 25.0 0.0013 LamG 2/2 431 565 .. 1 137 [] 96.7 2.7e-24 EGF_CA 4/5 590 624 .. 1 34 [] 14.0 0.031 EGF 5/8 591 624 .. 1 32 [] 23.4 0.031 EGF 6/8 626 662 .. 1 32 [] 26.0 0.0052 EGF_CA 5/5 628 662 .. 1 34 [] 6.3 0.27 EGF 7/8 668 717 .. 1 32 [] -8.9 1.5e+03 EGF 8/8 720 765 .. 1 32 [] -1.3 3.3e+02 HormR 1/1 767 829 .. 1 89 [] 83.4 2.7e-20 GPS 1/1 1110 1163 .. 1 51 [] 99.8 3.1e-25 Alignments of top-scoring domains: EGF: domain 1 of 8, from 26 to 81: score 27.1, E = 0.0024 *->eCa..pCsnGgtEqnGtCi..........................sy C+++pC+n +C++ + +++ + +++ ++ ++ ++ mKIAA0279 26 ICLrePCENY-----MRCVsvlrfdssapfiasssvlfrpihpvgGL 67 tC.CpgpGytg.rCe<-* +C+Cp pG+tg++Ce mKIAA0279 68 RCrCP-PGFTGdYCE 81 EGF: domain 2 of 8, from 86 to 119: score 31.1, E = 0.00015 *->eCa..pCsnGgtEqnGtCi....sytC.CpgpGytg.rCe<-* C ++pC+++ G+C++++++ytC C +Gytg++Ce mKIAA0279 86 LCYsrPCGPH-----GRCRsregGYTClCL-DGYTGeHCE 119 EGF_CA: domain 1 of 5, from 83 to 119: score 43.4, E = 3.1e-08 *->DiDEC...pCqnGGptgtCiN.vGSYrC.CppGyt.rnCe<-* +D C ++pC+++G +C+ ++G+Y+C C +Gyt+ +Ce mKIAA0279 83 EVDLCysrPCGPHG---RCRSrEGGYTClCLDGYTgEHCE 119 EGF_CA: domain 2 of 5, from 127 to 161: score 21.1, E = 0.004 *->DiDEC...pCqnGGptgtCiN..vGSYrC.Cpp.Gyt.rnCe<-* C++++C nGG tC+N vG+++C+Cp + ++++ C+ mKIAA0279 127 ----CtpgVCKNGG---TCVNllVGGFKCdCPSgDFEkPFCQ 161 EGF: domain 3 of 8, from 126 to 161: score 21.9, E = 0.09 *->eCa..pCsnGgtEqnGtCi.....sytC.CpgpGytg.rCe<-* C ++ C nG GtC++ ++++C+Cp+ ++ + C+ mKIAA0279 126 RCTpgVCKNG-----GTCVnllvgGFKCdCPSGDFEKpFCQ 161 LamG: domain 1 of 2, from 182 to 349: score 114.2, E = 1.5e-29 *->t.lsisfsFrTtspnGlLlyag....ggdflaleLvlEDsdgdGrlv ++++ +sF T + nGlLly+g+ ++++df+ale++ + +++ mKIAA0279 182 FhFTLALSFATKERNGLLLYNGrfneKHDFVALEVI------QEQVQ 222 lrydlGssttggparltsdsdrptplnDGqWHrVsvern........... l+++ G+ +++++++ p ++DGqWH+V++ +++++ ++++ + mKIAA0279 223 LTFSAGE----STTTVSPFV--PGGVSDGQWHTVQLKYYnkpllgqtglp 266 .....grsvtLsVDg...gnpvsges.................t.Ldldk +++++++ +++sVDg ++g + + ++ + ++++++++++Ldl+ mKIAA0279 267 qgpseQKVAVVSVDGcdtGVALRFGAmlgnyscaaqgtqggskKsLDLT- 315 eesgplylGGlPe.....lpvspgFrGCirnlrvngk<-* gpl lGG+P+ +++ + +F+GC+++l+v+++ mKIAA0279 316 ---GPLLLGGVPDlpesfPVRMRHFVGCMKDLQVDSR 349 EGF: domain 4 of 8, from 372 to 405: score 31.6, E = 0.0001 *->eCa..pCsnGgtEqnGtCi....sytC.CpgpGytg.rCe<-* C+++ C+nG GtC++ + ++C+Cp G+ g++C mKIAA0279 372 VCDssICHNG-----GTCVnqwnAFSCeCP-LGFGGkSCA 405 EGF_CA: domain 3 of 5, from 373 to 405: score 25.0, E = 0.0013 *->DiDEC...pCqnGGptgtCiN.vGSYrC.CppGyt.rnCe<-* C++++C+nGG tC+N+ + ++C+Cp G+ +++C mKIAA0279 373 ----CdssICHNGG---TCVNqWNAFSCeCPLGFGgKSCA 405 LamG: domain 2 of 2, from 431 to 565: score 96.7, E = 2.7e-24 *->t.lsisfsFrTtspnGlLlyag..ggdflaleLvlEDsdgdGrlvlr +++++s++FrT++++G+Ll+a ++g + ++l+L+ G++vl+ mKIAA0279 431 QpWHLSLMFRTRQADGVLLQAVtrGRSTITLQLR------AGHVVLS 471 ydlGssttggparltsdsdrptplnDGqWHrVsvern....grsvtLsVD ++ + +++l+ ++ + nDG WH+ ++ +++ +++ Ls D mKIAA0279 472 VEGTG---LQASSLRLEP---GRANDGDWHHAQLALGasggPGHAILSFD 515 ggnpvsges....t.LdldkeesgplylGGlPe..lpvspgFrGCirnlr + ++ +e + +++ l+ +++ +GG+P + + v gFrGC++++r mKIAA0279 516 -YGQQKAEGnlgpRlHGLH---LSNITVGGVPGpaSGVARGFRGCLQGVR 561 vngk<-* v + mKIAA0279 562 VSET 565 EGF_CA: domain 4 of 5, from 590 to 624: score 14.0, E = 0.031 *->DiDEC...pCqnGGptgtCiN.vGSYrC.CppGyt.rnCe<-* D C+++pC+ ++ C N+ SY+C+C Gy++ nC+ mKIAA0279 590 --DPCdsnPCPTNS---YCSNdWDSYSCsCVLGYYgDNCT 624 [output cut off at A = 10 top alignments] //