hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg05659/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0277  ( 584 res)   mbg05659

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RasGEF   Guanine nucleotide exchange factor for Ras-l   349.1   2.8e-100   1
RasGEFN  Guanine nucleotide exchange factor for Ras-l   131.4      1e-34   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RasGEFN    1/1      70   204 ..     1   172 []   131.4    1e-34
RasGEF     1/1     344   584 .]     1   261 []   349.1 2.8e-100

Alignments of top-scoring domains:
RasGEFN: domain 1 of 1, from 70 to 204: score 131.4, E = 1e-34
                   *->ckggliKgGtlekLiehLteardk.gkvdlkaDptfvetFLlTYRsF
                      ++++++ +Gt+ek++ehL+++++  + v+ k+ +t++++FLlTY +F
   mKIAA0277    70    SDRYVVVSGTPEKILEHLLNDLHLaE-VQHKETETLLDDFLLTYTVF 115  

                   ittqeLlqkLldrYnaippeivsrSlelkateaseglsfedysknaipvg
                   +tt +L+q+Ll++Y a +++                              
   mKIAA0277   116 MTTDDLCQALLRHYSAKKYQ------------------------------ 135  

                   faetdiivkekvnprriqnrVlnilrlWvenywedFeedpklnlfLeelf
                           +e+++ ++++++Vl+++++W+++y  +  ed ++++fL++++
   mKIAA0277   136 ------GEEENSDVPCRKRKVLHLVSQWISLYKDWLHEDEHSKMFLKTIY 179  

                   lelvedkkdkgpglekslanilerls<-*
                    ++++d + ++p lek+l++++++l+   
   mKIAA0277   180 RNVLDDVY-EYPILEKELKEFQKILG    204  

RasGEF: domain 1 of 1, from 344 to 584: score 349.1, E = 2.8e-100
                   *->lllldpeelAeQLTlldfelFrkIepsEllgsvwgkrskkspsplap
                      +l +++++lA  L+++d++lF++I+++El++++++++   +++    
   mKIAA0277   344    ILGMNTWDLALELMSFDWSLFNSIHEQELIYFTFSRQGNGENTV--- 387  

                   qnleafierfNevsnwVateIlkqttlkpkkRaevlskFIkVAkhcreLn
                    nl ++ +r+Nev+ wVateIl++ +  + kR+++++kFIk+A+hc+ ++
   mKIAA0277   388 -NLSLLLQRCNEVQLWVATEILLCSQ--LGKRVQLVKKFIKIAAHCKAQQ 434  

                   NFnSlmAIvsaLssspIsRLkkTWeklsskykklfeeLeelldpserNfk
                   N+nS++AIv++L+++++sRL+ TWek++ k+kklf+eLe+l+dps  N+k
   mKIAA0277   435 NLNSFFAIVMGLNTASVSRLSQTWEKIPGKFKKLFSELESLTDPS-LNHK 483  

                   nYReaLkscnkspnvqppcvPflGvyLkDLtfidegnpdflengtkglvN
                   +YR+a+k+++      pp++Pf++++LkD tfi+egn++fl+    +lvN
   mKIAA0277   484 AYRDAFKKMK------PPKIPFMPLLLKDVTFIHEGNKTFLD----NLVN 523  

                   FeKrrkiakilreirqlqsacqpynlkpnr.ndiqellrasrplevlpee
                   FeK+++ia+++r++r+++ +  + ++ p ++++++++ ++   l v++++
   mKIAA0277   524 FEKLHMIADTVRTLRHCRTNQFGSDVSPKEqQELKSYVNH---LYVIDSQ 570  

                   edelyelSlriEPrv<-*
                   +  l+elS+r+EPr    
   mKIAA0277   571 Q-ALFELSHRLEPRA    584  

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