hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/Pfam Sequence file: /cdna4/rodent/full/goal/msj/msj09203/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA0265 ( 412 res) msj09203 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- Kelch_1 Kelch motif 142.8 6.2e-39 5 Kelch_2 Kelch motif 106.0 7.5e-28 5 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- Kelch_1 1/5 61 118 .. 1 45 [] 29.9 6e-05 Kelch_2 1/5 61 118 .. 1 54 [] 17.8 0.26 Kelch_1 2/5 123 171 .. 1 45 [] 6.2 5.2 Kelch_2 2/5 123 171 .. 1 54 [] 16.0 0.92 Kelch_1 3/5 176 221 .. 1 45 [] 29.9 6e-05 Kelch_2 3/5 176 221 .. 1 54 [] 25.1 0.0016 Kelch_1 4/5 229 276 .. 1 45 [] 38.3 1.7e-07 Kelch_2 4/5 229 276 .. 1 54 [] 16.3 0.73 Kelch_1 5/5 285 330 .. 1 45 [] 42.0 1.3e-08 Kelch_2 5/5 285 330 .. 1 54 [] 31.5 2e-05 Alignments of top-scoring domains: Kelch_1: domain 1 of 5, from 61 to 118: score 29.9, E = 6e-05 *->pRsgagvvvldgkiYviGGydg.............qslnsvevYDpe +Rsg+ +v+ + +Yv+GGy+++ ++++++++++ ++ ++Y+ mKIAA0265 61 ARSGHRCVADNTNLYVFGGYNPdydesggpdnedyPLFRELWRYHFA 107 tntWtklpsmp<-* t+ W+++ + + mKIAA0265 108 TGVWHQMGTDG 118 Kelch_2: domain 1 of 5, from 61 to 118: score 17.8, E = 0.26 *->pryphasvvpggklyvvGGs..fkgnrgtgngdes..ssdllvldpe r++h +v + lyv+GG++++ ++g++++ +++ ++ l+++++ mKIAA0265 61 ARSGHRCVADNTNLYVFGGYnpDYDESGGPDNEDYplFRELWRYHFA 107 tnvWeklpalp<-* t vW+ + ++ mKIAA0265 108 TGVWHQMGTDG 118 Kelch_1: domain 2 of 5, from 123 to 171: score 6.2, E = 5.2 *->pRsgagvvvldgkiYviGGydg....qslnsvevYDpetntWtklps ++++ v +++ + v+GG + +++ n+v v +++ ++W l+ mKIAA0265 123 ELASMSLVLHGNNLLVFGGTGIpfgeSNGNDVHVCNVKYKRWALLSC 169 mp<-* + mKIAA0265 170 RG 171 Kelch_2: domain 2 of 5, from 123 to 171: score 16.0, E = 0.92 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW ++++++v+ g+ l+v+GG g + g + +d++v++ + ++W mKIAA0265 123 ELASMSLVLHGNNLLVFGGT-----GIPFGESNGNDVHVCNVKYKRW 164 eklpalp<-* l++ + mKIAA0265 165 ALLSCRG 171 Kelch_1: domain 3 of 5, from 176 to 221: score 29.9, E = 6e-05 *->pRsgagvvvldgkiYviGGydg.qslnsvevYDpetntWtklpsmp< + +g +++ ++g +Yv+GG +g ++ + ++D+ t Wt+l + + mKIAA0265 176 RIYGQAMALINGSLYVFGGTTGyIYSTDLHKLDLNTMVWTQLKPNN 221 -* mKIAA0265 - - Kelch_2: domain 3 of 5, from 176 to 221: score 25.1, E = 0.0016 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW + y++a+++++g lyv+GG g +s dl+ ld++t vW mKIAA0265 176 RIYGQAMALINGSLYVFGGT--------TGYIYSTDLHKLDLNTMVW 214 eklpalp<-* + l++ mKIAA0265 215 TQLKPNN 221 Kelch_1: domain 4 of 5, from 229 to 276: score 38.3, E = 1.7e-07 *->pRsgagvvvldgkiYviGGydg...qslnsvevYDpetntWtklpsm R+++ ++ + +iY+ GG ++ + sln++ +Y++etn W+++++ mKIAA0265 229 ERYRHEIAHDGQRIYILGGGTSwtaYSLNKIHAYNLETNAWEEIATK 275 p<-* p mKIAA0265 276 P 276 Kelch_2: domain 4 of 5, from 229 to 276: score 16.3, E = 0.73 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW ry+h ++ g+++y+ GG t + s+++++ +++etn+W mKIAA0265 229 ERYRHEIAHDGQRIYILGGG------TSWTAYSLNKIHAYNLETNAW 269 eklpalp<-* e+++ p mKIAA0265 270 EEIATKP 276 Kelch_1: domain 5 of 5, from 285 to 330: score 42.0, E = 1.3e-08 *->pRsgagvvvldgkiYviGGydg.qslnsvevYDpetntWtklpsmp< +R+++++v +++ ++++GGy+g+++l +++++++ t +W klp + mKIAA0265 285 ARRCHSCVQIKNDVFICGGYNGeVILGDIWKLNLQTFQWVKLPATM 330 -* mKIAA0265 - - Kelch_2: domain 5 of 5, from 285 to 330: score 31.5, E = 2e-05 *->pryphasvvpggklyvvGGsfkgnrgtgngdesssdllvldpetnvW r +h++v + + ++++GG+ ng + d++ l+++t +W mKIAA0265 285 ARRCHSCVQIKNDVFICGGY--------NGEVILGDIWKLNLQTFQW 323 eklpalp<-* klpa mKIAA0265 324 VKLPATM 330 //