hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm11192/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0259  ( 1569 res)   mpm11192

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
BRCT     BRCA1 C Terminus (BRCT) domain                 375.4     6e-109   7

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
BRCT       1/7     155   230 ..     1    96 []    67.8  2.2e-16
BRCT       2/7     249   325 ..     1    96 []    70.5  3.4e-17
BRCT       3/7     407   484 ..     1    96 []    63.4  4.8e-15
BRCT       4/7     605   677 ..     1    96 []    23.5   0.0048
BRCT       5/7     698   782 ..     1    96 []    52.3  1.1e-11
BRCT       6/7     956  1034 ..     1    96 []    55.2  1.4e-12
BRCT       7/7    1310  1388 ..     1    96 []    47.1  3.9e-10

Alignments of top-scoring domains:
BRCT: domain 1 of 7, from 155 to 230: score 67.8, E = 2.2e-16
                   *->p.eklfkgltfyltggldgfereeleleelieklGGkvtsslskktt
                      +   +++++t+++ ++ld+ +ree+  +++++++GG+v+ +l+ ++t
   mKIAA0259   155    VyNMIMSDVTVSC-TSLDKDKREEV--HKYVQMMGGRVYRDLNVSVT 198  

                   hvislvgepkypkieiifigsleagtskkllkakalgipivteeWlldci
                   h+i  +ge                g++k +l a +l++pi+ ++W++ ++
   mKIAA0259   199 HLI--AGEV---------------GSKK-YLVAANLKKPILLPSWIKTLW 230  

                   <-*
                      
   mKIAA0259     -     -    

BRCT: domain 2 of 7, from 249 to 325: score 70.5, E = 3.4e-17
                   *->p.eklfkgltfyltggldgfereeleleelieklGGkvtssl.skkt
                      +++++f g+++++ +gl g +r+ +  ++l  k+GG ++++l++ ++
   mKIAA0259   249    FkCPIFLGCIICV-TGLNGIHRKTV--QQLTAKHGGQYMGQLkMNEC 292  

                   thvislvgepkypkieiifigsleagtskkllkakalgipivteeWlldc
                   th+i  v+ep              +g +k ++ a ++++++vt +W+ d+
   mKIAA0259   293 THLI--VQEP--------------KG-QK-YECARRWNVHCVTLQWFHDS 324  

                   i<-*
                   i   
   mKIAA0259   325 I    325  

BRCT: domain 3 of 7, from 407 to 484: score 63.4, E = 4.8e-15
                   *->p.eklfkgltfyltggldgfereeleleelieklGGkvtsslskktt
                       +e+l+ g+++yl +g++g + ++l  ++li++ GG  +++l++++t
   mKIAA0259   407    ApEDLLDGCRIYL-CGFSGRKLDKL--RRLINSGGGVRFNQLNEDVT 450  

                   hvislvgepkypkieiifigsleagtskkllkakalgipivteeWlldci
                   hvi  vg+              +++ +  ++ + +++ ++v   Wll+c+
   mKIAA0259   451 HVI--VGDY-------------DDDVRQ-FWSKSSHRPHVVGAKWLLECF 484  

                   <-*
                      
   mKIAA0259     -     -    

BRCT: domain 4 of 7, from 605 to 677: score 23.5, E = 0.0048
                   *->p.eklfkgltfyltggldgfereeleleelieklGGkvtsslskktt
                       +e lf++++f +  g++ +++  +   ++i+++ Gk++s +s+ + 
   mKIAA0259   605    ReEGLFSQKSFLV-LGFSVENKCNI--VDIIREHAGKIVSLPSRIVA 648  

                   hvislvgepkypkieiifigsleagtskkllkakalgipivteeWlldci
                        v                  g++           ++vt  Wl+ ci
   mKIAA0259   649 DYA--VVPL--------------LGCEV-----DVTVGEVVTNTWLVTCI 677  

                   <-*
                      
   mKIAA0259     -     -    

BRCT: domain 5 of 7, from 698 to 782: score 52.3, E = 1.1e-11
                   *->p.eklfkgltfyltggldgfereeleleelieklGGkv.........
                      ++ ++++++++++ +   g er+ l   +l++ lG++v++   ++ +
   mKIAA0259   698    SgVTPLEDCVISF-SQCVGAERDSL--VFLANHLGASVqeffvrkan 741  

                   tsslskktthvislvgepkypkieiifigsleagtskkllkakalgipiv
                    +  +   th+i  v+ep               ++sk +++ak++ +p v
   mKIAA0259   742 AKKGMLASTHLI--VKEP---------------TGSK-YEAAKKWSLPAV 773  

                   teeWlldci<-*
                   +++Wll+     
   mKIAA0259   774 NISWLLETA    782  

BRCT: domain 6 of 7, from 956 to 1034: score 55.2, E = 1.4e-12
                   *->p.eklfkgltfyltggldgfereeleleelieklGGkvtsslskktt
                      ++ k++  +++++ +++ + +++el     + +lG+++  s+++++t
   mKIAA0259   956    EtRKPLDSVVVCV-SKKLSKKQSEL--NGVAASLGAEYRWSFDETVT 999  

                   hvislvgepkypkieiifigsleagtskkllkakalgipivteeWlldci
                   h+i + g+              ++ +++ ++ ak++g++iv+e Wll+c 
   mKIAA0259  1000 HFI-YQGRA-------------NDSNRE-YKSAKERGVHIVSEHWLLECA 1034 

                   <-*
                      
   mKIAA0259     -     -    

BRCT: domain 7 of 7, from 1310 to 1388: score 47.1, E = 3.9e-10
                   *->p.eklfkgltfyltggldgfereeleleelieklGGkv..tsslskk
                       + k+ k+++f   ++l ++er ++   +li++lGG+v + ++ +++
   mKIAA0259  1310    ThRKVKKQYVFQM-SSLNSQERIDY--CRLIKDLGGSVieKQCSDPS 1353 

                   tthvislvgepkypkieiifigsleagtskkllkakalgipivteeWlld
                   +th +  vg p               +++k +l+  a g+++++ ++l +
   mKIAA0259  1354 CTHMV--VGYP--------------LRNEK-YLASMAAGKWVLHRSYLDA 1386 

                   ci<-*
                   c    
   mKIAA0259  1387 CK    1388 

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