hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpg/mpg04132/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0224  ( 1224 res)   mpg04132

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N 
--------   -----------                                  -----    ------- ---
DUF1605    Domain of unknown function (DUF1605)         110.9    2.5e-29   1
HA2        Helicase associated domain (HA2)              95.5      1e-24   1
Helicase_C Helicase conserved C-terminal domain          61.4      2e-14   1
DEAD       DEAD/DEAH box helicase                        55.6    1.1e-12   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
DEAD         1/1     538   699 ..     1   266 []    55.6  1.1e-12
Helicase_C   1/1     771   865 ..     1    76 []    61.4    2e-14
HA2          1/1     919  1009 ..     1   124 []    95.5    1e-24
DUF1605      1/1    1043  1145 ..     1   140 []   110.9  2.5e-29

Alignments of top-scoring domains:
DEAD: domain 1 of 1, from 538 to 699: score 55.6, E = 1.1e-12
                RF    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   *->ptpiQaeaipaileneGfalredvlssggmdrlvlqApTGSGKTlaf
                       +++Q+e + +i   ++      v+        v +++TGSGKT+  
   mKIAA0224   538    IFAVQQELLTIIR--DN---S-IVI--------V-VGETGSGKTTQL 569  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   llPilygqrllkgpksarggksqgggknergfkidspqalvlaPTreLae
                      +   +    +                       +++ +  P+r  a+
   mKIAA0224   570 TQYLH--EDGYTDY----------------------GMIGCTQPRRVAAM 595  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   QiyeelkkllkilalsplgvnellrrigtglrvavlslyGGsslkdqldk
                    +++++++ ++                         +  G      ++  
   mKIAA0224   596 SVAKRVSEEMG-------------------------GNLG------EEVG 614  

                RF x xxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   l.rgkres.kggpdIvvgTPgrLldllrngrinikievssertgklklkn
                   +  ++++++++++ I ++T g Ll+                    l+  +
   mKIAA0224   615 YaIRFEDCtSENTLIKYMTDGILLRES------------------LREAD 646  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   lkhlkllVlDEahrlldmghgFgedleeilrrlprneplraqllgtilHq
                   l+h++ +++DEah+ + +++     l+e+++r+++   l+          
   mKIAA0224   647 LDHYSAVIMDEAHERSLNTDVLFGLLREVVARRSD---LK---------- 683  

                RF xxxxxxxxxxxxxxxxxxxxx   
                   kpniQtllfSATlpprevedl<-*
                        +++ SAT++ ++ + +   
   mKIAA0224   684 -----LIVTSATMDAEKFAAF    699  

Helicase_C: domain 1 of 1, from 771 to 865: score 61.4, E = 2e-14
                   *->ll.epgikvarlhGglsqeeReeilekFrsgkskvLvaTdvaarGlD
                      l ++p + v++++++l+++ + +i++k  +g +k++vaT++a+++l+
   mKIAA0224   771    LEnAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLT 817  

                   ipdvnlVInydl..................pwnpesyiQRiGRaGRaG<-
                   + ++ +VI+ ++ + +  +++ + +  +  p + ++  QR GRaGR G  
   mKIAA0224   818 VDGIMFVIDSGYcklkvfnprigmdalqiyPISQANANQRSGRAGRTG   865  

                   *
                    
   mKIAA0224     -   -    

HA2: domain 1 of 1, from 919 to 1009: score 95.5, E = 1e-24
                   *->aAlelLyeLgAlrDsdgeLTsplGrlmarlPldPrLgkmLvllaalf
                      ++   L +LgAl D+ g LT ++Grlm+++PldP L+kmL + ++  
   mKIAA0224   919    NSMYQLWILGAL-DNTGGLT-STGRLMVEFPLDPALSKML-IVSCDM 962  

                   gcldealiiaaiLsvrgspfvntGvDRdaqrlpldksekakrWNiSrdla
                   gc+ e+l+i+++Lsv + +f++          p +++e+ +     +   
   mKIAA0224   963 GCSSEILLIVSMLSV-PAIFYR----------PKGREEESD-----Q--I 994  

                   rakfegrsleksarsrltslsDhlall<-*
                   r+kf       + ++     sDhl++l   
   mKIAA0224   995 REKF-------AVPE-----SDHLTYL    1009 

DUF1605: domain 1 of 1, from 1043 to 1145: score 110.9, E = 2.5e-29
                   *->kQLlrilkrlglplnsssgdiellrkailaGlypNvArresdrggkg
                       QL++i+  + + l s++ d++++rk+i+a++++++A++     g g
   mKIAA0224  1043    AQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKL----KGIG 1085 

                   sYktlr.svrlpvrkkanisdvkdgeekgfktndgnVsiHPsSvLfntkk
                   +Y+ +r++ +                          +++HP+S+Lf+++ 
   mKIAA0224  1086 EYVNIRtGMP--------------------------CHLHPTSSLFGMGY 1109 

                   kppkwvvytel.vetskkgdgskvYardvtaispewllllapgki<-*
                   +p  ++vy+el ++t k      +Y+ +vta++ ewl++l+p  +   
   mKIAA0224  1110 TP-DYIVYHELvMTT-K------EYMQCVTAVDGEWLAELGP-MF    1145 

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