hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mib/mib13036/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0216  ( 2048 res)   mib13036

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
MYSc     Myosin. Large ATPases.                         171.6    7.9e-47   1
PDZ      Domain present in PSD-95, Dlg, and ZO-1/2.      47.9    1.3e-09   1
IQ       Short calmodulin-binding motif containing co    26.8      0.003   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PDZ        1/1     242   324 ..     1    80 []    47.9  1.3e-09
MYSc       1/1     412  1195 ..     1   771 []   171.6  7.9e-47
IQ         1/1    1196  1218 ..     1    23 []    26.8    0.003

Alignments of top-scoring domains:
PDZ: domain 1 of 1, from 242 to 324: score 47.9, E = 1.3e-09
                   *->gglGfsivg.............gifvssvvpG.spAakaGrkslglL
                      g +Gfs++ ++  ++ ++++    +v   +pG +  + a +     L
   mKIAA0216   242    GDFGFSLRRttmldrapegqayRRVVHFAEPGaGTKDLALG-----L 283  

                   kvGDvIleVNGetsvegltheeavdllkkaggggvGekvtLtvlRgg<-*
                    +GD+++e+NG ++ve+++ +e+v++++++g+     +v+L+v++ +   
   mKIAA0216   284 VPGDRLVEING-QNVENKSRDEIVEMIRQSGD-----SVRLKVQPIP    324  

MYSc: domain 1 of 1, from 412 to 1195: score 171.6, E = 7.9e-47
                   *->rnppkfegVeDmvlLtyLnEpavlhNLkkRYlkdlIYTYiGlvLvav
                       n p ++  eD++ L yLnE +vlh+L++RY   l +TY+G+ L ++
   mKIAA0216   412    ANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVL 458  

                   NPYkqlppiYtdevikkYrekkdldGksrgElpPHvFAiADeAYrnMlre
                      +  p +Y++ v+++++      G++r++++PH++A+A  AYr+Ml  
   mKIAA0216   459 -STRGAPAVYSEKVMHMFK------GCRREDMAPHIYAVAQTAYRAMLMS 501  

                   keNQsIiISGESGAGKTEatKkimqYLAavsg....svesve..dqiLes
                   +++QsI+  G SG+GKT +  ++ qYLA ++g+++++v sve+ + +   
   mKIAA0216   502 RQDQSIVLLGSSGSGKTTSFQHLVQYLATIAGtsgtKVFSVEkwQALST- 550  

                   NPiLEAFGNAKTvRNnNSSRFGKfieIhFdekGkivGAkIenYLLEKSRV
                     +LEAFGN  T+ N    RF     + Fd+ G +  A+I + LLEK RV
   mKIAA0216   551 --LLEAFGNSPTIMNGSATRFSQILSLDFDQAGQVASASIQTMLLEKLRV 598  

                   VsQakgERNYHIFYQLLaGaseelkkelgLskFSksped..YkYLnqggt
                    + +  E  + +FY+LLa  ++ l+ el+L +    +e++ +  +  ++ 
   mKIAA0216   599 ARRPASEATFNVFYYLLACGDATLRTELHLNH---LAENnvFGIVPLSK- 644  

                   pfankryssgcltvdgiDDaeeFkeTdEvtlkAmrvlGfseeEqesIFri
                                 +    a+ F +    ++ Am+vl +s eEq  ++ i
   mKIAA0216   645 ------------PEEKQKAAQQFSK----LQAAMKVLAISPEEQKTCWLI 678  

                   lAAILHLGNieFeegrntgdnaavtslkvadeeelqkaAeLLgvdpeeLe
                   lA+I HLG    ++++   ++a+  ++  a +e +qkaA+LLg++ eeL 
   mKIAA0216   679 LASIYHLGAAGATKEA---AEAGRKQF--ARHEWAQKAAYLLGCSLEELS 723  

                   kaL.........tkRkiktggeggsvitkpl...nveqAvyaRDALAKai
                    a+ +++ ++++++R++  + +      + l+++++  A+     +A ++
   mKIAA0216   724 SAIfkhqlkggtLQRSTSFRQG---PEESGLgegTKLSALECLEGMASGL 770  

                   YsRLFdWLVkrINksl.....sayfIGVLDIyGFEiFekN..........
                   Ys LF  L++ +N++l+++++s  ++ + D  GF     N++ +++ ++ 
   mKIAA0216   771 YSELFTLLISLVNRALkssqhSLCSMMIVDTPGF----QNpewggsarga 816  

                   SFEQfCINyaNEKLQQfFnqhvFKlEQEEYerEGIeWtf..IdFfliDNQ
                   SFE +C Nya  +LQ +F +++F +E E Y++  Ie  f++ + +  D  
   mKIAA0216   817 SFEELCHNYAQDRLQRLFHERTFLQELERYKEDNIELAFddLEPVADDSV 866  

                   pciD....LIEkKg..krPlGIlslLDEeClfHAqPkgTDqtFleKLnka
                   +++D+ ++L+   ++  +  G+l lL+Ee l+   P +T + +l++L   
   mKIAA0216   867 AAVDqashLVRSLAhaDEARGLLWLLEEEALV---PGATEDALLDRL--- 910  

                   lyhqhhkkhphfskprkSlkk.gkp.kkrfgrtaFiikHYAGd..VtYnv
                        ++     ++     kk++ p  +  + ++F + H  G++ V+Ynv
   mKIAA0216   911 -----FSYYGPQEGD----KKgQSPlLRSSKPRHFLLGHSHGTnwVEYNV 951  

                   eGFL...eKNkDtLfedlieLlqsSknpliasLFpeeadqsssaakekss
                    G+L+ +  N  +  ++   Llq S+ ++i +LF   a++++        
   mKIAA0216   952 AGWLnytKQN--PATQNAPRLLQDSQKKIISNLFLGRAGSAT-------- 991  

                   ggagksrkagrreps.k...................gt..i.sskkrppT
                               ++s++  + +++++   ++ ++ ++t + ++   ++++
   mKIAA0216   992 ------------VLSgSiagleggsqlalrratsmrKTftTgMAAVKKKS 1029 

                   vGsqFk.sLneLmetLnstnPHFIRCIKPNeeKkpg..............
                   +  q+k +   L++t+  +  HF+ C  P  e  pg++++ ++++ ++++
   mKIAA0216  1030 LCIQIKlQVDALIDTIKRSKMHFVHCFLPVAEGWPGeprsassrrvssss 1079 

                   ...............vFdaslVlhQLrylGvLEniRIRraGFPyRlpfde
                   + + +++++ + +  + d sl + QLr + +L++ R  r G+P  + f+e
   mKIAA0216  1080 eldlppgdpceagllQLDVSLLRAQLRGSRLLDAMRMYRQGYPDHMVFSE 1129 

                   FlqRYkvLlpktwppwggewknr..lfgdakkacealLqslglgiegdnl
                   F++R+ vL+p   +  g     r+    d+k a+e lL+sl        l
   mKIAA0216  1130 FRRRFDVLAPHLTKKHG-----RnyIVVDEKRAVEELLESLD-------L 1167 

                   deeeyqiGkTKvFlRnpgqlaeLEelRee<-*
                   +++   +G + vF+R +g+la+LEe+R+e   
   mKIAA0216  1168 EKSSCCLGLSRVFFR-AGTLARLEEQRDE    1195 

IQ: domain 1 of 1, from 1196 to 1218: score 26.8, E = 0.003
                   *->rleraAiiIQaawRGylaRkryk<-*
                      +  r  +++Qaa+RGylaR+++k   
   mKIAA0216  1196    QTSRHLTLFQAACRGYLARQHFK    1218 

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