hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mid/mid01021/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0177  ( 1269 res)   mid01021

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PARP     Poly(ADP-ribose) polymerase catalytic domain   259.9    3.3e-74   1
VWA      von Willebrand factor type A domain             50.9    2.8e-11   1
BRCT     BRCA1 C Terminus (BRCT) domain                  45.7      1e-09   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
BRCT       1/1      16    96 ..     1    96 []    45.7    1e-09
PARP       1/1     386   574 ..     1   245 []   259.9  3.3e-74
VWA        1/1     884  1051 ..     1   195 []    50.9  2.8e-11

Alignments of top-scoring domains:
BRCT: domain 1 of 1, from 16 to 96: score 45.7, E = 1e-09
                   *->p.eklfkgltfyl.tggldgfereeleleelieklGGkvtsslskkt
                       +  +f +++f+l+ + l+ +++++l  +  i+++GGk++  l++++
   mKIAA0177    16    MtLGIFANCIFCLkVKYLPRQQKKKL--QTDIKENGGKFSFLLNPQC 60   

                   thvislvgepkypkieiifigsleagtskk.llkakalgipivteeWlld
                   thvi  v++               + +s  +l+ ++++ + i ++ ++ d
   mKIAA0177    61 THVI--VDSA--------------DVLSRChLNSIQKNDVQIANPAFIQD 94   

                   ci<-*
                   ++   
   mKIAA0177    95 SV    96   

PARP: domain 1 of 1, from 386 to 574: score 259.9, E = 3.3e-74
                   *->LkcklepLdkdSeEykiiekylknThapthggynaYsytildIfrvq
                      L+ck+e++d+++eE++++ k+++++ ++ +      +++il+Ifrv 
   mKIAA0177   386    LRCKIEHVDQNTEEFSRVRKEVLQNNRSEQ------PVDILQIFRVG 426  

                   rdgewerFqpkkkqleknglhNinrrLLWHGSrltNfagILsqGLriapp
                   r +e+  F  k        l+N  +rLL+HGS++ N++gILs+GL+ +  
   mKIAA0177   427 RVNEATEFLSK--------LGN--VRLLFHGSPVRNILGILSRGLLLPKV 466  

                   eapvtGym.D.G.FGkGiYFAdmaSkSaDnYcptsvsegcphngsglyrs
                     +++  ++D G++G+GiYF+d +S S+  Y ++ +      +gs+l   
   mKIAA0177   467 AEDRGVQRtDvGnLGSGIYFSDSLSTSI-KYAHAGET-----DGSRL--- 507  

                   tlgmlLceVaLGdemneLtkadysaeklppgkhsvkGlGkttPawkdpse
                      +++c+VaLG+ + +L+k+d+s++++ppg++sv+G++ tt+       
   mKIAA0177   508 ---LVVCDVALGK-CVNLFKKDFSLTEAPPGYDSVHGVSETTS------- 546  

                   sfvdlDGvvvPlgklvstlydssvdntllynEYVVYdveQvrlkYLlevk
                            vP++              ++ +E+VVY+++Qv++kY+++++
   mKIAA0177   547 ---------VPTD--------------FQDDEFVVYKTNQVKMKYIVKFC 573  

                   f<-*
                   +   
   mKIAA0177   574 T    574  

VWA: domain 1 of 1, from 884 to 1051: score 50.9, E = 2.8e-11
                   *->DivFllDgSgSigeenlFekvkdFvkklveknldigpdgtrVglvqY
                       +++ lD+S+S+ +   F ++k+ +   ++     + +   V+++q+
   mKIAA0177   884    EVIICLDCSSSMEGVT-FTQAKQVALYALS----LLGEEQKVNIMQF 925  

                   ssdvrtefsLndysskddllaavlknlrylgGgTnNtgkALkyalenlfs
                   ++  ++ fs  +  + +++     +   ++ G+T+   k L+y   ++ s
   mKIAA0177   926 GTGYKELFSYPKCITDSKMATEFIMSAAPSMGNTD-FWKVLRYLSLLYPS 974  

                   stMikrnrsagsRpenapkvlillTDGksndggdve.aaaalrdkkkgvg
                   +         g R       ++l++DG+ ++++++ + +++  +     +
   mKIAA0177   975 E---------GFRN------ILLISDGHLQSESLTLqLVKRNIQH---TR 1006 

                   itvfavGvGgdvdeaeLr.iasepeseghvfyvedfdalwlelqdiqeql
                   +++ avG+   ++++ Lr+++ ++     +f+ +++++ w +  +i+ q+
   mKIAA0177  1007 VFTCAVGS--TANRHILRtLSQCGAGVFEYFNSKSKHS-WKK--QIEAQM 1051 

                   <-*
                      
   mKIAA0177     -     -    

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