hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mpj/mpj02836/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0175  ( 648 res)   mpj02836

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    364.4   7.2e-105   1
TyrKc    Tyrosine kinase, catalytic domain               52.8    2.1e-14   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
S_TKc      1/1      16   268 ..     1   231 []   364.4 7.2e-105
TyrKc      1/1      16   268 ..     1   280 []    52.8  2.1e-14

Alignments of top-scoring domains:
S_TKc: domain 1 of 1, from 16 to 268: score 364.4, E = 7.2e-105
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik........erilrE
                      Yel +++G G+F+kV+la ++ tg+ vAiK+++++  +++  r++ E
   mKIAA0175    16    YELYETIGTGGFAKVKLACHVLTGEMVAIKIMDknalgsdlPRVKTE 62   

                   ikiLkk.dHPNIVkLydvfed.dklylVmEyceGdlGdLfdllkkrgrrg
                   i+ Lk+ +H +I++Ly v e+++k+++V+Eyc+G  G+Lfd++ ++ r  
   mKIAA0175    63 IDALKSlRHQHICQLYHVLETkNKIFMVLEYCPG--GELFDYIISQDR-- 108  

                   lrkvlsE.earfyfrQilsaLeYLHsqgIiHRDLKPeNiLLds..hvKla
                       lsE+e+r +frQilsa++Y Hsqg  HRDLKPeN+L+d+++ +Kl+
   mKIAA0175   109 ----LSEeETRVVFRQILSAVAYVHSQGYAHRDLKPENLLFDEnhKLKLI 154  

                   DFGlArql........ttfvGTpeYmAPEvl...gYgkpavDiWSlGcil
                   DFGl+++ +++++ +  t++G++ Y APE++++++Y + ++D+WS G++l
   mKIAA0175   155 DFGLCAKPkgnkdyhlQTCCGSLAYAAPELIqgkSYLGSEADVWSMGILL 204  

                   yElltGkpPFp..qldlifkkig..........SpeakdLikklLvkdPe
                   y l++G  PF+++++++++kki++++++ +++ Sp+ + L++++L++dP+
   mKIAA0175   205 YVLMCGFLPFDddNVMALYKKIMrgkyevpkwlSPSSILLLQQMLQVDPK 254  

                   kRlta.eaLedeldikaHPff<-*
                   kR++ + +L+       HP++   
   mKIAA0175   255 KRISMrNLLN-------HPWV    268  

TyrKc: domain 1 of 1, from 16 to 268: score 52.8, E = 2.1e-14
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda....keeFlrE
                       +l +++G G F +V ++    ++++VA+K + ++a ++++     E
   mKIAA0175    16    YELYETIGTGGFAKVKLACHVltgEMVAIKIMDKNAlgsdLPRVKTE 62   

                   akiMkklGgkHpNiVkLlGvcteegrrFmevePlmivmEymegGdLldyL
                   +  +k+l  +H++i +L+ v  ++         +++v+Ey++gG L dy+
   mKIAA0175    63 IDALKSL--RHQHICQLYHVLETK-------NKIFMVLEYCPGGELFDYI 103  

                   rknrpklslsdLlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenkvvK
                    +  + ls ++      QI +  +Y +s+++ HRDL   N L +en+  K
   mKIAA0175   104 ISQDR-LSEEETRVVFRQILSAVAYVHSQGYAHRDLKPENLLFDENHKLK 152  

                   IsDFGLsRdlyddDkkGeskdyYrkkggkggktllPirWmAPEslkdgkF
                     DFGL+ + +         + Y+ ++  ++     +   APE ++ + +
   mKIAA0175   153 LIDFGLCAKPKGN-------KDYHLQT--CC---GSLAYAAPELIQGKSY 190  

                   .tskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGyRlpk
                     s+ DVWS G+lL+ ++  G  P  +      +   +++++++G++  +
   mKIAA0175   191 lGSEADVWSMGILLY-VLMCGFLPFDD-----DNVMALYKKIMRGKYEVP 234  

                   PendlpiSsvtCPdelYdlMlqCWaedPedRPtFsel..verl<-*
                               ++    l +q  + dP++R ++++l ++      
   mKIAA0175   235 KWL---------SPSSILLLQQMLQVDPKKRISMRNLlnHPWV    268  

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