hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpj/mpj02836/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0175  ( 648 res)   mpj02836

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       336.2    3.8e-97   1
KA1         Kinase associated domain 1                   82.1    1.1e-20   1
Pkinase_Tyr Protein tyrosine kinase                      68.9    1.1e-16   1
Kdo         Lipopolysaccharide kinase (Kdo/WaaP) fami   -86.6       0.53   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Kdo           1/1      10   190 ..     1   223 []   -86.6     0.53
Pkinase_Tyr   1/1      16   266 ..     1   272 []    68.9  1.1e-16
Pkinase       1/1      16   268 ..     1   287 []   336.2  3.8e-97
KA1           1/1     599   648 .]     1    50 []    82.1  1.1e-20

Alignments of top-scoring domains:
Kdo: domain 1 of 1, from 10 to 190: score -86.6, E = 0.53
                   *->defWqlqgkvvgeanGRrttwFvvaeklFGvngalrhYyRGglwgkL
                      de+    +k ++  ++ +t+ F   ++         h   G + +  
   mKIAA0175    10    DEL----LKYYELYETIGTGGFAKVKL-------ACHVLTGEMVAIK 45   

                   vrDryrfpGlgrtrsvrEfrllrrLreaGvpVPkpvAagavkvgleryqA
                   + D   + G + +r   E ++l+ Lr   +  ++ v   + k + +    
   mKIAA0175    46 IMD-KNALGSDLPRVKTEIDALKSLRHQHICQLYHV--LETKNKIF---- 88   

                   dLLtEklegaqDLvtwlaqWaddPpaeelrqalweavGrlIakmHragvn
                     + E  +g +  + +  q   d+++ee ++ + +++  ++a  H+ g  
   mKIAA0175    89 -MVLEYCPGGELFDYIISQ---DRLSEEETRVVFRQILSAVAYVHSQGYA 134  

                   HtDLnahnILldqeesvegkfkvwlIDfdKcrrrlrvgdrWreknLarLk
                   H+DL + n L+d+        k+ lIDf  c+ +   g+++    L    
   mKIAA0175   135 HRDLKPENLLFDENH------KLKLIDFGLCAKPK--GNKDYH--LQT-- 172  

                   RSflKErGkrsigfteaDwaallrg..Y<-*
                             + g       +l++g++Y   
   mKIAA0175   173 ----------CCGSLAYAAPELIQGksY    190  

Pkinase_Tyr: domain 1 of 1, from 16 to 266: score 68.9, E = 1.1e-16
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtL.ke.igassee
                       +l +++G G F +V ++        t+  VA+K+++k+ +g++ + 
   mKIAA0175    16    YELYETIGTGGFAKVKLACHV----LTGEMVAIKIMdKNaLGSDLP- 57   

                   ieredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegG
                           E+  +k+l +H++i +L+ v    +      +++V+Ey++gG
   mKIAA0175    58 ----RVKTEIDALKSL-RHQHICQLYHVLET-KNK----IFMVLEYCPGG 97   

                   dLldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcL
                    L d+  +   +++L+ ++   + +Qi ++ +Y +s+++ HRDL   N L
   mKIAA0175    98 ELFDYIIS---QDRLSEEETRVVFRQILSAVAYVHSQGYAHRDLKPENLL 144  

                   VsenlvVKIsDFGLaRdi.ynddyYvrkkgggklPvkWmAPEslkygkF.
                    +en++ K  DFGL+   + n+dy +++           APE ++ + + 
   mKIAA0175   145 FDENHKLKLIDFGLCAKPkGNKDYHLQTCC---GSLAYAAPELIQGKSYl 191  

                   tskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPenC
                    s+ DVWS G+lL+ ++  G  P + +  +  +++++ +  y  p+    
   mKIAA0175   192 GSEADVWSMGILLYVLMC-GFLP-FDDDNVMALYKKIMRGKYEVPKWL-- 237  

                   PdelYdlMlqCWaedPedRPtFselverL<-*
                   ++    l +q  + dP++R +++ l+++    
   mKIAA0175   238 SPSSILLLQQMLQVDPKKRISMRNLLNHP    266  

Pkinase: domain 1 of 1, from 16 to 268: score 336.2, E = 3.8e-97
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr
                      yel e++G G+f++V++a+h+ tg++VA+Ki++k    s+ ++ ++ 
   mKIAA0175    16    YELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSDLPRVKT- 61   

                   rsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrlldLfdylse
                     Ei  lk+L+H +I++l++v e+k+++ +VlEyc+gG    +Lfdy+  
   mKIAA0175    62 --EIDALKSLRHQHICQLYHVLETKNKIFMVLEYCPGG----ELFDYII- 104  

                   trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldengv
                     ++ +l  se+e + +++Qil++++Y Hs+g  HRDLKPeN+L+den  
   mKIAA0175   105 --SQDRL--SEEETRVVFRQILSAVAYVHSQGYAHRDLKPENLLFDENHK 150  

                   vdaflKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggngygtkvD
                   +    K++DFGl++k + +++ +l+t +G++ Y+APE+++g ++ g+++D
   mKIAA0175   151 L----KLIDFGLCAKPKGnKDYhLQTCCGSLAYAAPELIQGKSYLGSEAD 196  

                   vWSlGvilyelltGkpPFsgevqdsldqlqlirkilgpplefdspewdsi
                   vWS+G++ly l++G +PF+++     + ++l++ki+++++e + + +   
   mKIAA0175   197 VWSMGILLYVLMCGFLPFDDD-----NVMALYKKIMRGKYEVPKWLS--- 238  

                   srsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                               ++ + L+  +L++DP+kR++ + +l+HPw+   
   mKIAA0175   239 ------------PSSILLLQQMLQVDPKKRISMRNLLNHPWV    268  

KA1: domain 1 of 1, from 599 to 648: score 82.1, E = 1.1e-20
                   *->ddksksvvkFEiqlyKlprldlyGvdfqRisGpqwlFkdLcsailne
                      +d++k++++FE+++++l+r+d++G+++qR++G++w++k+L+++il+ 
   mKIAA0175   599    SDFGKVTMQFELEVCQLQRPDVVGIRRQRLKGDAWVYKRLVEDILSG 645  

                   Lkv<-*
                   +k    
   mKIAA0175   646 CKM    648  

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