hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj34112/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0167  ( 1029 res)   mfj34112

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
ArfGap   Putative GTPase activating protein for Arf     219.3    5.8e-62   1
PH       PH domain                                       55.1    1.5e-12   1
Ank      Ankyrin repeat                                  34.6    2.2e-06   2
Ras      Ras family                                     -21.4    7.5e-07   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Ras        1/1     265   425 ..     1   174 []   -21.4  7.5e-07
PH         1/1     534   747 ..     1    92 []    55.1  1.5e-12
ArfGap     1/1     768   888 ..     1   137 []   219.3  5.8e-62
Ank        1/2     927   959 ..     1    33 []    28.6  0.00014
Ank        2/2     960   992 ..     1    33 []     6.2       26

Alignments of top-scoring domains:
Ras: domain 1 of 1, from 265 to 425: score -21.4, E = 7.5e-07
                   *->KlVlvGDgGVGKSsLliRFtdnkFp..eeYipTIGv.DFytktvevd
                       l ++GD   GKSsL +RF ++++   e+    I +++ y k + vd
   mKIAA0167   265    RLGVLGDVRSGKSSLIHRFLTGSYQvlEK----I-EsEQYKKEMLVD 306  

                   gktvkLqIWDTAGQErFralrpaYYRgAqGfLLVYDITsrdSFenvkkWl
                   g+t    I      E+  a    +   A++++ V++  +++SF+ v + +
   mKIAA0167   307 GQTHLVLIR-----EEAGAPDAKFSGWADAVIFVFSLEDESSFQAVSRLH 351  

                   eeilrhad..kdenvpivLVGNKcDLeddedlele.kqkRqVsteeGeal
                    ++    ++++      +LVG+  D  +       +   R+V  ++++al
   mKIAA0167   352 GQLSSLRGegRGG-LALALVGTQ-DRIS------AsSP-RVVGDARARAL 392  

                   AkelgAlpFmETSAKtneNVeeaFeelareilk<-*
                   + +++ + ++ET A  + NV+ +F+e+a+++     
   mKIAA0167   393 CTDMKRCSYYETCATYGLNVDRVFQEVAQKVVT    425  

PH: domain 1 of 1, from 534 to 747: score 55.1, E = 1.5e-12
                   *->vikeGwLlkkg...gkkswkkRyfvLfndvLlyykdkk.....kkpk
                      +ik+ +Llk+++++ +k+wkk y++L ++ +l+y ++ ++  ++++ 
   mKIAA0167   534    PIKQSFLLKRSgnsLNKEWKKKYVTLSSNGFLLYHPSIndyihSTHG 580  

                   gsipLsgiqvekvpdn..................................
                   + ++L   +v+ + + +++  +  +++ + ++  ++ ++ + +++++ ++
   mKIAA0167   581 KEMDLLRTTVKVPGKRppraisafgpsasinglvkdmstvqmgegpeast 630  

                   ..................................................
                   + +++++++++ + ++++++++  +++++  +  +++ +++++ ++ +++
   mKIAA0167   631 pmpspspspsslqlptdqtskhllkpdrnlaralstdctpsgdlsplsre 680  

                   .............................krkncFeirt.dretlllqae
                   +++++  +++++++ +++++++++  + +++++ F i++++++t++++a+
   mKIAA0167   681 pppspmvkkqrrkklstpsktegsavqaeEENFEFLIVSsTGQTWHFEAA 730  

                   seeerkeWvkaiqsair<-*
                   s eer+ Wv+ai+s+i    
   mKIAA0167   731 SFEERDAWVQAIESQIL    747  

ArfGap: domain 1 of 1, from 768 to 888: score 219.3, E = 5.8e-62
                   *->qrvlqlLrsldpgNkkCfDCgavpnPtWaSvnlGvflCieCSGiHRn
                      + ++q +r+ + gN+ C DCga pnPtWaS+nlG+++CieCSGiHRn
   mKIAA0167   768    AVAIQAIRNAK-GNSTCVDCGA-PNPTWASLNLGALICIECSGIHRN 812  

                   LfGvHiSkVnvRSltLDsWtpeeLrklesckgGNenansfwEsnlddfsl
                   L G+H+S+V  RSl+LD W++ eL +++ +++GN+ an++wEs+ + +++
   mKIAA0167   813 L-GTHLSRV--RSLDLDDWPR-ELTLVL-TAIGNDTANRVWESDTRGRAK 857  

                   kpkdsdaaavKCqddrqkyesfiaaKYeeklfvlkeeqee<-*
                   +++ds+         r+++es+i+aKYe++lf+ +++  e   
   mKIAA0167   858 PTRDSS---------REERESWIRAKYEQLLFLAPLGTTE    888  

Ank: domain 1 of 2, from 927 to 959: score 28.6, E = 0.00014
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                        ++PLHlAa+  ++ + +lLl +GAd+ a+d    
   mKIAA0167   927    QLRSPLHLAAELAHVVITQLLLWYGADVAARDA    959  

Ank: domain 2 of 2, from 960 to 992: score 6.2, E = 26
                   *->dGfTPLHlAalrgnlevvklLlsqGAdlnaqdd<-*
                       G+T+L +A + g+  ++  Ll++G+          
   mKIAA0167   960    QGRTALFYARQAGSQLCADILLQHGCPGEGGST    992  

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