hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs Sequence file: /cdna4/rodent/full/goal/mbj/mbj00784/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mKIAA0148 ( 722 res) mbj00784 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- ArfGap Putative GTP-ase activating proteins for the 206.5 2.4e-57 1 ANK ankyrin repeats 33.9 2.1e-05 3 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- ArfGap 1/1 41 166 .. 1 139 [] 206.5 2.4e-57 ANK 1/3 174 203 .. 1 30 [] 7.6 4.5e+02 ANK 2/3 208 237 .. 1 30 [] 14.0 21 ANK 3/3 241 270 .. 1 30 [] 12.3 68 Alignments of top-scoring domains: ArfGap: domain 1 of 1, from 41 to 166: score 206.5, E = 2.4e-57 *->eealqlLRsikpgNkkCfDCGavpnPtWaSvnlGvflCieCSGiHRs +++++LRs++ +C+DC+ p+P WaSvn+G+f+C eC+++HRs mKIAA0148 41 GTMSKRLRSSD----VCADCNG-PDPSWASVNRGTFICDECCSVHRS 82 LfGvHiSkVnvRSltLDtWteeeLrllesckgGNenansfwesnlddfsl L G+HiS+V R+l++++W+++ L+++e +++N++ans+we+ l d+++ mKIAA0148 83 L-GRHISQV--RHLKHTAWPPTLLQMVE--TLYNNGANSIWEHSLLDPAS 127 kpkdsda.aasv.KCeddrqkyesfiaaKYeeklfrvdkesaee<-* +++++ ++a++++K +++++ +fi+aKY++++f v++++++e mKIAA0148 128 IMSGR-RkANPQdK---VHPNKAEFIRAKYQMLAF-VHRLPCRE 166 ANK: domain 1 of 3, from 174 to 203: score 7.6, E = 4.5e+02 *->dGrTpLHlAaengnlevvklLldkgadina<-* d LH +++gnle++ Ll+ ga n mKIAA0148 174 DLSKQLHSSVRTGNLETCLRLLSLGAQANF 203 ANK: domain 2 of 3, from 208 to 237: score 14.0, E = 21 *->dGrTpLHlAaengnlevvklLldkgadina<-* G TpLH+A + g++ ++lL +gad+ mKIAA0148 208 KGSTPLHVASKAGQILQAELLAVYGADPGT 237 ANK: domain 3 of 3, from 241 to 270: score 12.3, E = 68 *->dGrTpLHlAaengnlevvklLldkgadina<-* G+Tp +A + g++e+++ L++ ++++ mKIAA0148 241 SGKTPVDYARQGGHHELAERLIEIQYELTD 270 //