hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mia/mia05011/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0137  ( 570 res)   mia05011

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    264.1    1.1e-74   1
TyrKc    Tyrosine kinase, catalytic domain               -7.8    1.2e-10   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TyrKc      1/1     260   536 ..     1   280 []    -7.8  1.2e-10
S_TKc      1/1     260   538 ..     1   231 []   264.1  1.1e-74

Alignments of top-scoring domains:
TyrKc: domain 1 of 1, from 260 to 536: score -7.8, E = 1.2e-10
                   *->ltlgkkLGeGaFGeVykGtlk...ieVAVKtLkeda..........k
                        l++ LG+G F eVyk+    +++  AVK  + +++ +++++++ +
   mKIAA0137   260    YLLLHLLGRGGFSEVYKAFDLyeqRYAAVKIHQLNKswrdekkenyH 306  

                   eeFlrEakiMkklGgkHpNiVkLl.GvcteegrrFmevePlmivmEymeg
                   +  +rE +i k+l  +Hp iVkL++   ++        +  + v+Ey+eg
   mKIAA0137   307 KHACREYRIHKEL--DHPRIVKLYdYFSLDT-------DTFCTVLEYCEG 347  

                   GdLldyLrknrpklslsdLlsfAlQIAkGMeYLesk..nfvHRDLAARNc
                    dL+ yL+ ++   s ++  s+  QI +  +YL + +++++H DL   N+
   mKIAA0137   348 NDLDFYLKQHKL-MSEKEARSIVMQIVNALRYLNEIkpPIIHYDLKPGNI 396  

                   Lvgenk...vvKIsDFGLsRdlyddDkkGeskdyYrkkggkggktllPir
                   L+ ++   + +KI+DFGLs+  +dd + G+ +   ++    +g     + 
   mKIAA0137   397 LLVDGTacgEIKITDFGLSKIMDDD-SYGVDGMDLTS----QGA--GTYW 439  

                   WmAPEslkdg....kFtskSDVWSFGVlLWEiftlGeqPYpgeiqq.fms
                    ++PE++  g++++k + k DVWS GV  +  + +G +P      q+++ 
   mKIAA0137   440 YLPPECFVVGkeppKISNKVDVWSVGVIFF-QCLYGRKPFGHNQSQqDIL 488  

                   neevleylkkGyRlpkPendlpiSsvtCPdelYdlMlqCWaedPedRPtF
                    e  + +  +   + kP           ++e    +++C a+  edR   
   mKIAA0137   489 QENTILKATEVQFPVKPVV---------SSEAKAFIRRCLAYRKEDRFDV 529  

                   selverl<-*
                    +l  +    
   mKIAA0137   530 HQLANDP    536  

S_TKc: domain 1 of 1, from 260 to 538: score 264.1, E = 1.1e-74
                   *->YellkklGkGaFGkVylardkktgrlvAiKvik..............
                      Y ll +lG+G+F++Vy+a d   +r+ A+K+   +++ +++++++ +
   mKIAA0137   260    YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQlnkswrdekkenyh 306  

                   erilrEikiLkk.dHPNIVkLydvfed..dklylVmEyceGdlGdLfdll
                   ++++rE +i+k+ dHP IVkLyd+f  ++d ++ V+EyceG   dL  +l
   mKIAA0137   307 KHACREYRIHKElDHPRIVKLYDYFSLdtDTFCTVLEYCEG--NDLDFYL 354  

                   kkrgrrglrkvlsE.earfyfrQilsaLeYLHsq..gIiHRDLKPeNiLL
                   k+++       +sE+ear+++ Qi++aL YL + ++ IiH DLKP NiLL
   mKIAA0137   355 KQHKL------MSEkEARSIVMQIVNALRYLNEIkpPIIHYDLKPGNILL 398  

                   ds.....hvKlaDFGlArql.............ttfvGTpeYmAPEvl..
                    +++  +++K++DFGl++++++++ + ++ + ++   GT +Y++PE +  
   mKIAA0137   399 VDgtacgEIKITDFGLSKIMdddsygvdgmdltSQGAGTYWYLPPECFvv 448  

                   .....gYgkpavDiWSlGcilyElltGkpPFp.........qldlifkki
                   ++++++ +  +vD+WS+G+i++ +l+G+ PF +++++++  q+++i+k  
   mKIAA0137   449 gkeppKISN-KVDVWSVGVIFFQCLYGRKPFGhnqsqqdilQENTILKAT 497  

                   g.........SpeakdLikklLvkdPekRlta.eaLedeldikaHPff<-
                       + ++  S+eak +i+++L +  e+R  ++++ +       +P++  
   mKIAA0137   498 EvqfpvkpvvSSEAKAFIRRCLAYRKEDRFDVhQLAN-------DPYL   538  

                   *
                    
   mKIAA0137     -   -    

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