hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mia/mia05011/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0137  ( 570 res)   mia05011

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       229.6    4.5e-65   1
Pkinase_Tyr Protein tyrosine kinase                      35.3    4.5e-14   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase_Tyr   1/1     260   536 ..     1   272 []    35.3  4.5e-14
Pkinase       1/1     260   538 ..     1   287 []   229.6  4.5e-65

Alignments of top-scoring domains:
Pkinase_Tyr: domain 1 of 1, from 260 to 536: score 35.3, E = 4.5e-14
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtLk..........
                        l++ LG+G F eVyk+        ++   AVK+   +++ +++++
   mKIAA0137   260    YLLLHLLGRGGFSEVYKAFDL----YEQRYAAVKIHQlnkswrdekk 302  

                   eigasseeieredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyi
                   e +++ ++       rE +i k+l dHp iV+L+ + + + +      + 
   mKIAA0137   303 E-NYHKHA------CREYRIHKEL-DHPRIVKLYDYFSLDTDT----FCT 340  

                   VtEymegGdLldfLrkhregrpLtlkdLlsfalQiAkGMeYLeskn..fv
                   V+Ey+eg dL+ +L++h   +  + k+  s+ +Qi +++ YL + +++++
   mKIAA0137   341 VLEYCEGNDLDFYLKQH---KLMSEKEARSIVMQIVNALRYLNEIKppII 387  

                   HRDLAARNcLVse...nlvVKIsDFGLaRdiynddyYvrkkgggklPv..
                   H DL   N+L+ +++  + +KI+DFGL++ + +dd Y  + g      + 
   mKIAA0137   388 HYDLKPGNILLVDgtaCGEIKITDFGLSKIM-DDDSY-GVDGMDLTSQga 435  

                   ..kWm.APEslkygk....FtskSDVWSFGVlLWEiftlGeqPF.....Y
                   ++ W+ +PE++  gk++++ + k DVWS GV  +  +  G++PF+++++ 
   mKIAA0137   436 gtYWYlPPECFVVGKeppkISNKVDVWSVGVIFFQCLY-GRKPFghnqsQ 484  

                   pgmsneevlellyedGyRLprPenCPdelYdlMlqCWaedPedRPtFsel
                   +++  e ++ + +e     ++    + e    +++C a+  edR    +l
   mKIAA0137   485 QDILQENTILKATEVQFPVKPVV--SSEAKAFIRRCLAYRKEDRFDVHQL 532  

                   verL<-*
                    ++    
   mKIAA0137   533 ANDP    536  

Pkinase: domain 1 of 1, from 260 to 538: score 229.6, E = 4.5e-65
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKi..ikkrkekskkdkta
                      y ll  lG+G+f++Vyka +  +++  AvKi++++k+ +++kk+ ++
   mKIAA0137   260    YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIhqLNKSWRDEKKENYH 306  

                   rrr.sEiqilkrLsHpNIvrlidvfed.kdhlylVlEycegGLrlldLfd
                    ++ +E +i+k+L+Hp Iv+l+d+f  + d  + VlEyceg     dL  
   mKIAA0137   307 KHAcREYRIHKELDHPRIVKLYDYFSLdTDTFCTVLEYCEGN----DLDF 352  

                   ylsetrrkgpllfsedeakkialQilrgleYLHsn..giiHRDLKPeNIL
                   yl+   +++ +  se+ea++i+ Qi+ +l YL + ++ iiH DLKP NIL
   mKIAA0137   353 YLK---QHKLM--SEKEARSIVMQIVNALRYLNEIkpPIIHYDLKPGNIL 397  

                   ldengvvdaflKiaDFGlAkkls.....t.sss.lttfvGTpwYmAPEvl
                   l+ +g+ +  +Ki+DFGl+k +++++ + +    ++  +GT+wY++PE  
   mKIAA0137   398 LV-DGTACGEIKITDFGLSKIMDddsygVdGMDlTSQGAGTYWYLPPECF 446  

                   l...ggngygtkvDvWSlGvilyelltGkpPFs.gevqds.ldqlqlirk
                     +++ ++++ kvDvWS+Gvi+++ l G+ PF +++   s+ d lq    
   mKIAA0137   447 VvgkEPPKISNKVDVWSVGVIFFQCLYGRKPFGhNQ---SqQDILQENTI 493  

                   ilgpplefdspewdsisrsefrrlpnlseeakdLikkcLnkDPskRltae
                    + +++ f+   + s             +eak +i++cL++  ++R   +
   mKIAA0137   494 LKATEVQFPVKPVVS-------------SEAKAFIRRCLAYRKEDRFDVH 530  

                   eilqHPwf<-*
                   ++ ++P++   
   mKIAA0137   531 QLANDPYL    538  

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