hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh03533/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0131  ( 935 res)   mbh03533

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGAP   RhoGAP domain                                  223.5      3e-63   1
FCH      Fes/CIP4 homology domain                        78.5    1.4e-19   1
SH3_1    SH3 domain                                      53.7    4.1e-12   1
SH3_2    Variant SH3 domain                              46.1      8e-10   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
FCH        1/1       1   103 [.     1   107 []    78.5  1.4e-19
RhoGAP     1/1     512   665 ..     1   155 []   223.5    3e-63
SH3_1      1/1     740   794 ..     1    58 []    53.7  4.1e-12
SH3_2      1/1     741   794 ..     1    69 []    46.1    8e-10

Alignments of top-scoring domains:
FCH: domain 1 of 1, from 1 to 103: score 78.5, E = 1.4e-19
                   *->dgFwselnsddgykaLlkrlddglrlledlkkFlreRakiEeeYAkk
                       +++++l  ++++++L+ + + +++ll++l++F+r+Ra++E eY++ 
   mKIAA0131     1    -EMRWQL--SEQLHCLELQGELRRDLLQELAEFMRRRAEVELEYSRG 44   

                   LqklskkyfnkkRkSdgsvskdsltekgpdslsslkkawnvllsetdqls
                   L kl++++ +++ + +gs+ + ++++k+p+ ls+l ++w+vll++t q+s
   mKIAA0131    45 LDKLAERFTSRSGRLGGSSQEQQSFRKEPTLLSPL-HCWAVLLEHTRQQS 93   

                   klHsqlseqL<-*
                   +   +lse L   
   mKIAA0131    94 RESAALSEVL    103  

RhoGAP: domain 1 of 1, from 512 to 665: score 223.5, E = 3e-63
                   *->PlivekCieflekrGLdtEGIyRvsGsksrikeLreafdrgedvdln
                      Pl+ve+Ci+f+  +GL+ EGI+RvsG ++ri e+r+af+rged+ ++
   mKIAA0131   512    PLVVESCIRFINLNGLQHEGIFRVSGAQARISEIRDAFERGEDPLEK 558  

                   dleeedvhvvAslLKlFLReLPePLltfelyeefieaaaksedeeerlea
                       +d  +vA++LKl++R+L  PL++ ++++e+++  a++e   er+e 
   mKIAA0131   559 GCTVHDLDSVAGVLKLYFRSLEPPLFPLDMFNELLA-SAELEVVGERVEP 607  

                   lrellrkLPpaNrdtLryLlahLnrVaqnsevNkMtahNLAivFgPtLlr
                   ++ ll kLP++   +LryL+ +Ln+ aq+s++N+M+++NLA++FgPtLl+
   mKIAA0131   608 VSHLLFKLPRPVLVVLRYLFTFLNHLAQYSDENMMDSYNLAVCFGPTLLP 657  

                   ppdgdsad<-*
                    p+g+ +    
   mKIAA0131   658 VPAGQDPV    665  

SH3_1: domain 1 of 1, from 740 to 794: score 53.7, E = 4.1e-12
                   *->kkvvALYDYearesdELsFkkGDvitvleksddgWWkgrlkgtgGke
                        +vA ++Y++r+++EL+F++GDv+ + ++  ++WW+g+     G +
   mKIAA0131   740    LEAVACFAYTGRTAQELTFQRGDVLRLYARASSDWWRGEHA---GVQ 783  

                   GliPsNYVepv<-*
                   GliP+ Y+++    
   mKIAA0131   784 GLIPHKYITLC    794  

SH3_2: domain 1 of 1, from 741 to 794: score 46.1, E = 8e-10
                   *->ygraiedyvaAtdknenleeeeLslkkGdvvkvidvggskdddgwwl
                       ++a++ y++ + ++e      L++++Gdv++++     + + +ww+
   mKIAA0131   741    EAVACFAYTG-RTAQE------LTFQRGDVLRLY----ARASSDWWR 776  

                   geslggGrrrRGlvPssaveel<-*
                   ge    G+   Gl+P++++  +   
   mKIAA0131   777 GEH--AGVQ--GLIPHKYITLC    794  

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