hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mph/mph00209/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0123  ( 509 res)   mph00209

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N 
--------        -----------                             -----    ------- ---
Peptidase_M16   Insulinase (Peptidase family M16)       237.1    2.4e-67   1
Peptidase_M16_C Peptidase M16 inactive domain           163.1    4.9e-45   1
LNS2            LNS2 (Lipin/Ned1/Smp2)                  -63.5       0.89   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
Peptidase_M16     1/1      61   211 ..     1   160 []   237.1  2.4e-67
Peptidase_M16_C   1/1     216   415 ..     1   198 []   163.1  4.9e-45
LNS2              1/1     392   504 ..     1   159 []   -63.5     0.89

Alignments of top-scoring domains:
Peptidase_M16: domain 1 of 1, from 61 to 211: score 237.1, E = 2.4e-67
                   *->rVasesdppadtsavglwidaGSryEpddnnGlAHFLEHmaFkGTkk
                      rVas+++  +++++vg++i++GSryE +++ G+AHFLE++aF++T++
   mKIAA0123    61    RVASQNK-FGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSSTAR 106  

                   ypseneleeeleklGGslaRDvNAyTsrEhTvYyvevlnddkqkllpkav
                   + s++e+ ++lek+GG++     ++Tsr+ T+Y v+++++     l+++v
   mKIAA0123   107 FDSKDEILLTLEKHGGIC----DCQTSRDTTMYAVSADSKG----LDTVV 148  

                   DrLadvllnPlftesevererlvvlyEveavdaeprpqevlldnlhaaay
                   D+Ladv+l+P++t++e+e++r++v++E+e+ +++p+p+++l++++h+aa+
   mKIAA0123   149 DLLADVVLHPRLTDEEIEMTRMAVQFELEDLNMRPDPEPLLTEMIHEAAF 198  

                   rgtpLgrsllgPg<-*
                   r++++g++ ++P    
   mKIAA0123   199 RENTVGLHRFCPV    211  

Peptidase_M16_C: domain 1 of 1, from 216 to 415: score 163.1, E = 4.9e-45
                   *->sltredLkdFykkhYspdnmvlvvvGdvdhdellalaekyfgdlpas
                      +++re L+++ k++Y+pd+mvl++vG v+h+ l+++a+ky+ + +  
   mKIAA0123   216    KIDREVLHSYLKNYYTPDRMVLAGVG-VEHEHLVECARKYLVGAEPA 261  

                   kekalvpplneAkgkpr.pprepakl.g.evvvp.k.........dv.pq
                   ++          ++   +++r +a+++g+++ v+++ ++ + +++++++ 
   mKIAA0123   262 WG----------APGTVdVDRSVAQYtGgIIKVErDmsnvslgptPIpEL 301  

                   ahlalafpgpplsddpdsaaldvLnelLggg......g.g.gmsSrLfqe
                   +h++++++ +++  + d +++ vLn+++ggg++ + +g+g+gm SrL+ +
   mKIAA0123   302 THIMVGLESCSF-LEDDFIPFAVLNMMMGGGgsfsagGpGkGMFSRLYLN 350  

                   lrekegLpaysvsafndsysyndddtGlfgiya.tdpegenleeRvleli
                   +++++++  y++ ++++sy+    dtGl+ i+a++dp   ++ e ++e i
   mKIAA0123   351 VLNRHHW-MYNATSYHHSYE----DTGLLCIHAsADPR--QVRE-MVEII 392  

                   leeleklaeeGiteeeleraknql<-*
                    +e+  + ++ ++  elerak+ql   
   mKIAA0123   393 TKEFILMGRT-VDLVELERAKTQL    415  

LNS2: domain 1 of 1, from 392 to 504: score -63.5, E = 0.89
                   *->vViSDIDGTITkSDvLGHvlpiiGkDPWthaGVadLyr....kiqen
                               ITk       + ++G++       +dL+  ++ k q  
   mKIAA0123   392    ---------ITKE------FILMGRT-------VDLVEleraKTQLM 416  

                   GYkIiYLTaRaiGQadrTrsYLsqvkQdGknLPdGpViLSPdrlfaALkR
                     +++ L +R++   d+ r+ L+ +   + +LP+ +  L          R
   mKIAA0123   417 SMLMMNLESRPVIFEDVGRQVLATH---SRKLPHELCTLI---------R 454  

                   EvIekkPeeFKiacLrdIrnlFppdngnpFyAGFGNritDvisYraVgvp
                   +v   kPe+ K  + + +r         p +A+ G   tD  +Y+++   
   mKIAA0123   455 NV---KPEDIKRVASKMLRGK-------PAVAALGDL-TDLPTYEHIQAA 493  

                   psrIFtInpkgevhqe<-*
                    s      ++g + ++   
   mKIAA0123   494 LS-----SRNGHLPRS    504  

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