hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mni/mni13228/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0118  ( 253 res)   mni13228

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RAB      Rab subfamily of small GTPases                 258.2    6.4e-73   1
RAS      Ras subfamily of RAS small GTPases             127.4    1.6e-33   1
RHO      Rho (Ras homology) subfamily of Ras-like sma    41.9    1.2e-12   1
RAN      Ran (Ras-related nuclear proteins) /TC4 subf    34.4    6.5e-06   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RAB        1/1      49   212 ..     1   172 []   258.2  6.4e-73
RAS        1/1      46   212 ..     1   167 []   127.4  1.6e-33
RHO        1/1      51   212 ..     1   180 []    41.9  1.2e-12
RAN        1/1      54   244 ..     1   202 []    34.4  6.5e-06

Alignments of top-scoring domains:
RAB: domain 1 of 1, from 49 to 212: score 258.2, E = 6.4e-73
                   *->FKiilIGDSGVGKSsLLsRFtddkFsedsksTIGVDFktktievdGk
                      FK++l+G+ +VGK+sL++R++++kF+++++ T  + F+tk ++++Gk
   mKIAA0118    49    FKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGK 95   

                   rvKLQIWDTAGQERFRSiTssYYRGAvGalLVYDiTnreSFenlknWlke
                   rv L IWDTAGQERF+++ + YYR+++Ga+LVYD+T+++SF+++knW+ke
   mKIAA0118    96 RVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKE 145  

                   lreyadpppenvvimLVGNKsDLeeqRqVstEeaekficDcAeehgllFi
                   lr++ ++    ++  +VGNK+DLe++R+Vs +eae +    Ae  g + +
   mKIAA0118   146 LRKMLGN---EICLCIVGNKIDLEKERHVSIQEAESY----AESVGAKHY 188  

                   fETSAKtntNVeeAFeelakkIlkr<-*
                     TSAK n  +ee F+ l k+++ +   
   mKIAA0118   189 -HTSAKQNKGIEELFLDLCKRMIET    212  

RAS: domain 1 of 1, from 46 to 212: score 127.4, E = 1.6e-33
                   *->mreYKlVVlGgGGVGKSALTiQFiqghFvdeYDPTIEDSY.RKqiei
                         +K+V lG G VGK++L+++ +++ F d++  T   S+ +K+ +i
   mKIAA0118    46    AYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFlTKKLNI 92   

                   DgevalLDILDTAGQeEFsAMRdqYmRtGeGFlLVYSitsrqSFeeikkf
                    g+ + L I DTAGQe F A+   Y R+ +G +LVY +t+ +SF+ +k+ 
   mKIAA0118    93 GGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNW 142  

                   reqIlRVKdrddvPivLVGNKcDLeneRqVsteEGkeLAkqlncpFlEtS
                    + +  + ++ ++ + +VGNK DLe eR+Vs +E+++ A++ +++ + tS
   mKIAA0118   143 VKELRKMLGN-EICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTS 191  

                   AKerinVdeaFydLVReirks<-*
                   AK++  ++e F dL +++      
   mKIAA0118   192 AKQNKGIEELFLDLCKRMIET    212  

RHO: domain 1 of 1, from 51 to 212: score 41.9, E = 1.2e-12
                   *->lVvVGDGaVGKTCLLisYTtnaFPedYVPTVFENYsadvev......
                      +V+ G G+VGKT+L  +Y +n+F         + ++++++ +  +++
   mKIAA0118    51    VVLLGEGCVGKTSLVLRYCENKF--------NDKHITTLQAsfltkk 89   

                   ..pDgkpvnLgLWDTAGQEdYDRLRPLSYPqtDVfLiCFSVdspaSfeNV
                    + +gk+vnL+ WDTAGQE +  L P  Y +++  ++ ++V+  +Sf+ V
   mKIAA0118    90 lnIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKV 139  

                   keKWyPEvkhfcPnvPii.LVGtKlDLRnDedtleelsekkqePvtteqG
                   k+ W+ E++    n  ++  VG+K+DL   ++ +   +e ++        
   mKIAA0118   140 KN-WVKELRKMLGNEICLcIVGNKIDLE--KERHVSIQEAES-------- 178  

                   eanskialAkeIGAvkYlECSAltqeGvkeVFeeAiraaLnk<-*
                           A ++GA k+  +SA++++G++e F    +  ++    
   mKIAA0118   179 -------YAESVGA-KHYHTSAKQNKGIEELFLDLCKRMIET    212  

RAN: domain 1 of 1, from 54 to 244: score 34.4, E = 6.5e-06
                   *->vGDGGtGKttFvKRHLtGEFEKKYvatlGvEvHPLvFftnrGkirFn
                       G+G  GKt  v R     F  K + tl              ++   
   mKIAA0118    54    LGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLA 100  

                   vWDtAGqEKFGGLRDGYYiqgqCAiimFDvtaRvtYKnvPnWHRDLvRvC
                   +WDtAGqE+F  L   YY  +  Ai+++Dvt    ++ v nW ++L ++ 
   mKIAA0118   101 IWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKML 150  

                   En.iPivLCGnKvDv.KdRkvKAKqi.tFHRKKnLqYYdisAKsnYnFEK
                    n+i + + GnK+D++K+R+v  ++ + +      + Y  sAK n   E 
   mKIAA0118   151 GNeICLCIVGNKIDLeKERHVSIQEAeSYAESVGAKHYHTSAKQNKGIEE 200  

                   PFLyLARKLlGDpnLeFvamPALAPPEvqlDiAlaakyEkDLeaAaa.aa
                    FL L ++++                  q+D  ++ +      aA ++ +
   mKIAA0118   201 LFLDLCKRMIETA---------------QVDERAKGNGSSQAGAARRgVQ 235  

                   LPDddDDdl<-*
                   + Dd+  +    
   mKIAA0118   236 IIDDEPQAQ    244  

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