hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg10506/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0093  ( 904 res)   mbg10506

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
HECT     HECT-domain (ubiquitin-transferase)            601.4   5.2e-177   1
WW       WW domain                                      163.8    2.9e-45   3
C2       C2 domain                                      107.2    3.2e-28   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
C2         1/1      97   183 ..     1    88 []   107.2  3.2e-28
WW         1/3     268   297 ..     1    30 []    60.9  2.7e-14
WW         2/3     424   453 ..     1    30 []    55.3  1.3e-12
WW         3/3     479   508 ..     1    30 []    60.4  3.9e-14
HECT       1/1     598   903 ..     1   366 []   601.4 5.2e-177

Alignments of top-scoring domains:
C2: domain 1 of 1, from 97 to 183: score 107.2, E = 3.2e-28
                   *->LrVtvieAknLppkDfkngksDPYVkvslggdkkd.qk.kkTkvikk
                      +rV+vi + +L++kD + g sDPYV+v+l +  ++  ++ +Tk+ikk
   mKIAA0093    97    VRVKVIAGIGLAKKD-ILGASDPYVRVTLYDPMSGiLTsVQTKTIKK 142  

                   tlNPvWNEtFtFevpppdlqetLeieVyDydrfgrddflGevs<-*
                   +lNP+WNE+  F  ++p+ ++ + +eV+D++r++rddflG+v    
   mKIAA0093   143 SLNPKWNEEILFR-VLPQRHR-ILFEVFDENRLTRDDFLGQVD    183  

WW: domain 1 of 3, from 268 to 297: score 60.9, E = 2.7e-14
                   *->LppgWeerkdpdGrpYYyNhnTktTqWekP<-*
                      LppgWeer d  Gr+YY+Nh++++TqW +P   
   mKIAA0093   268    LPPGWEERQDVLGRTYYVNHESRRTQWKRP    297  

WW: domain 2 of 3, from 424 to 453: score 55.3, E = 1.3e-12
                   *->LppgWeerkdpdGrpYYyNhnTktTqWekP<-*
                      LppgWee  d+ Gr YY++hn+ktT+W kP   
   mKIAA0093   424    LPPGWEEKQDDRGRSYYVDHNSKTTTWSKP    453  

WW: domain 3 of 3, from 479 to 508: score 60.4, E = 3.9e-14
                   *->LppgWeerkdpdGrpYYyNhnTktTqWekP<-*
                      LppgWeer++ dGr++++Nhn k+TqWe+P   
   mKIAA0093   479    LPPGWEERTHTDGRVFFINHNIKKTQWEDP    508  

HECT: domain 1 of 1, from 598 to 903: score 601.4, E = 5.2e-177
                   *->tLlsrelfnPdygLFeysdnseakseeddsysgyvedsytlfpnPls
                      +L+s+e+fnP+ygLFeys                ++d+ytl++nP+s
   mKIAA0093   598    FLISKEMFNPYYGLFEYS----------------ATDNYTLQINPNS 628  

                   gesnpehervlkyFkflGrilGlAlydgrllDlpFsraFyKklLmagkps
                   g +n++h   l+yFkf+Gr+ G+A+y+g+llD +F r+FyK++L  +k  
   mKIAA0093   629 GLCNEDH---LSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMML--QKL- 672  

                   igivtleDlesvDPelynSLkwllendgdKkIedsLLgsledveedLeLt
                      +tl+D+esvD+e+y SL+w+lend++                +L+L 
   mKIAA0093   673 ---ITLHDMESVDSEYYSSLRWILENDPT----------------ELDLR 703  

                   FsveeessvgfeadarffGgtktveELkPnGrnipVTneNkeeYvelyvd
                   F ++ee    f       G+t ++e Lk +G++i VTn+Nk+eY+ l+++
   mKIAA0093   704 FIIDEEL---F-------GQTHQHE-LKTGGSEIVVTNKNKKEYIYLVIQ 742  

                   yrLnkgiekQfeAFrkGFsevipsrlLslFdpeELelLicGspeeiDvdd
                   +r+ ++i+kQ+ AF++GF e+ip +l+++Fd++ELelL+cG++ ++Dv+d
   mKIAA0093   743 WRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLG-DVDVND 791  

                   LkenTeYdggYtedsplktiqwFWevleeftneeraklLqFvTGssRlPv
                   ++e+T+Y++gY+++++  +i+wFW+++  +++e+r +lLqFvTG+sR+P+
   mKIAA0093   792 WREHTKYKNGYSMNHQ--VIHWFWKAVWMMDSEKRIRLLQFVTGTSRVPM 839  

                   gGFkaLqgGsnGpPkFtIvrkegggdddrLPtAhTCFNrLkLPpYsSkei
                   +GF++L+ GsnGp++Ft++ +   g++d LP+AhTCFNrL+LPpY+S + 
   mKIAA0093   840 NGFAELY-GSNGPQSFTVEQW---GTPDKLPRAHTCFNRLDLPPYESFDE 885  

                   LrekLllAInEgseGFgle<-*
                   L +kL +AI E+++GF+ +   
   mKIAA0093   886 LWDKLQMAI-ENTQGFDGV    903  

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