hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj52294/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0089  ( 363 res)   mfj52294

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N 
--------       -----------                              -----    ------- ---
NAD_Gly3P_dh_C NAD-dependent glycerol-3-phosphate deh   293.0    3.6e-84   1
NAD_Gly3P_dh_N NAD-dependent glycerol-3-phosphate deh   259.5    4.5e-74   1
F420_oxidored  NADP oxidoreductase coenzyme F420-depe   -51.9       0.25   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
NAD_Gly3P_dh_N   1/1      18   189 ..     1   175 []   259.5  4.5e-74
F420_oxidored    1/1      19   242 ..     1   252 []   -51.9     0.25
NAD_Gly3P_dh_C   1/1     206   356 ..     1   160 []   293.0  3.6e-84

Alignments of top-scoring domains:
NAD_Gly3P_dh_N: domain 1 of 1, from 18 to 189: score 259.5, E = 4.5e-74
                   *->kkiaVlGaGsWGTALAkvLadngk.lpdeFeheVrlWgreeki.Gee
                       k++++G+G+WG+A+Ak+++ n k+l  +F  +V +W++ee+++G++
   mKIAA0089    18    LKVCIVGSGNWGSAVAKIIGSNVKtLQ-KFSSTVKMWVFEETVnGRK 63   

                   lieeINttreNvrYLPGikLPdnlvAttDLeeAlkdAdiivlaVPsqalr
                   l+++IN+++eNv+YLPG+kLP+n+vA+++L eA+ dAd++v+++P+q+++
   mKIAA0089    64 LTDIINNDHENVKYLPGHKLPENVVAVPNLSEAVQDADLLVFVIPHQFIH 113  

                   evlkqlkgllkkdaiivsltKGii.gEpgtlkllSevieEeLpiqprqia
                    +++++ g ++++a  + l+KGi++g   +lkl+S++i+E ++i+   i+
   mKIAA0089   114 KICDEITGRVPEKALGITLIKGIDeGPD-GLKLISDIIREKMGID---IS 159  

                   VLSGPslAeEVAkglptavvvAsekdqqaae<-*
                   VL+G+++A+EVA++++++++++s k +q      
   mKIAA0089   160 VLMGANIASEVAAEKFCETTIGS-KVMQNGL    189  

F420_oxidored: domain 1 of 1, from 19 to 242: score -51.9, E = 0.25
                   *->kIGiIGGaGnmGeaLArglaaaGvlppheviiansRdpekaaalaee
                      k+ i+ G+Gn G+a+A+              i+  ++ ++++++  +
   mKIAA0089    19    KVCIV-GSGNWGSAVAK--------------II-GSNVKTLQKFSST 49   

                   lg...................................vildagatavsne
                   +     +++ ++++ ++  ++++++ +  ++++ +++v     a++ + +
   mKIAA0089    50 VKmwvfeetvngrkltdiinndhenvkylpghklpenV----VAVP-NLS 94   

                   eAaeeaDvviLAVppeaapevlael.........................
                   eA+++aD+ ++ +p + + + ++e++++ +++  + +  ++ ++++++ +
   mKIAA0089    95 EAVQDADLLVFVIPHQFIHKICDEItgrvpekalgitlikgidegpdglk 144  

                   .aadllkgklVIsitngitieqleqyllrVvRVMPNTpslvgrgasglaa
                     +d+ ++k  I+i++ ++                               
   mKIAA0089   145 lISDIIREKMGIDISVLMG------------------------------- 163  

                   gdpvegsaselvaellpgvGkvveVpervvkAfnaisasglaylalpvea
                     +    ase +ae + +               ++i++++++   l+ e 
   mKIAA0089   164 --AN--IASEVAAEKFCE---------------TTIGSKVMQNGLLFKEL 194  

                   ladaavl.vggddaeAkklvaqladGAAkMllesgehPaqLkddvtGfgg
                   l+ +       dda+  +l+ +l +                   v  +g+
   mKIAA0089   195 LQTPNFRiTVVDDADTVELCGALKN------------------IV-AVGA 225  

                   vdiGgLrvlerleprtp<-*
                     + gLr +       +   
   mKIAA0089   226 GFCDGLRCGDNTKAAVI    242  

NAD_Gly3P_dh_C: domain 1 of 1, from 206 to 356: score 293.0, E = 3.6e-84
                   *->eDvvGvEigGALKNViAIAaGivDGkeylgfGdNaKAalitrGLaEm
                      +D ++vE++GALKN++A++aG++DG   l  GdN+KAa+i++GL+Em
   mKIAA0089   206    DDADTVELCGALKNIVAVGAGFCDG---LRCGDNTKAAVIRLGLMEM 249  

                   iklgaalGggpeetaTffgLaGlGDLitTCtselsRNrrvGeaLgkgGIl
                   i+++++++ g   taTf++++G++DLitTC++  +RNrrv+ea++++G  
   mKIAA0089   250 IAFAKIFCKGQVSTATFLESCGVADLITTCYG--GRNRRVAEAFARTG-- 295  

                   ksleeiekelselnGqvaEGvkTakevyelakrkglvedmPlteaVYril
                   k++ee+ekel  lnGq+++G+ T +evy+++++kgl++++Pl++aVY+i+
   mKIAA0089   296 KTIEELEKEL--LNGQKLQGPQTSAEVYRILRQKGLLDKFPLFTAVYQIC 343  

                   yeglkpeeaieeL<-*
                   yeg ++++ + +L   
   mKIAA0089   344 YEGRPVTQMLSCL    356  

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