hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg05662/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0067  ( 1162 res)   mbg05662

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
SET      SET (Su(var)3-9, Enhancer-of-zeste, Trithora   153.0    3.1e-41   1
PreSET   N-terminal to some SET domains                 149.1    4.6e-40   1
MBD      Methyl-CpG binding domain                      125.0    8.2e-33   1
TUDOR    Tudor domain                                    88.8    6.7e-22   2

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TUDOR      1/2     112   174 ..     1    60 []    41.6  1.1e-07
TUDOR      2/2     202   257 ..     1    60 []    47.5  1.7e-09
MBD        1/1     471   546 ..     1    87 []   125.0  8.2e-33
PreSET     1/1     553   658 ..     1   124 []   149.1  4.6e-40
SET        1/1     675  1143 ..     1   114 []   153.0  3.1e-41

Alignments of top-scoring domains:
TUDOR: domain 1 of 2, from 112 to 174: score 41.6, E = 1.1e-07
                   *->pkfkvGdlvaarwse.DgewYrArIikvdse..nqlyeVffiDyGne
                       k+ vG  v+a+++++++ w  A I++ +++ +n+l +++f+D+G+ 
   mKIAA0067   112    DKLFVGSRVVAKYKDgNQVWLYAGIVAETPNvkNKLRFLIFFDDGYA 158  

                   evvplsdlrqlpekfa<-*
                   ++v  s l++++++++   
   mKIAA0067   159 SYVTQSELYPICRPLK    174  

TUDOR: domain 2 of 2, from 202 to 257: score 47.5, E = 1.7e-09
                   *->pkfkvGdlvaarwseDgewYrArIikvdsenqlyeVffiDyGneevv
                      + +k G+l+++ w  +g+w++ r+++vd+  +l++++f+D+  +e++
   mKIAA0067   202    VLLKSGQLIKTEW--EGTWWKSRVEEVDG--SLVRILFLDDKRCEWI 244  

                   plsdlrqlpekfa<-*
                   ++++ r++p +++   
   mKIAA0067   245 YRGSTRLEPMFSM    257  

MBD: domain 1 of 1, from 471 to 546: score 125.0, E = 8.2e-33
                   *->edelrlPaLppGWrRetvqRksgKKssagkgDVyYisPcGkkLRsks
                      +++l +P L++++rR+t++R+++   ++++++V+Y++PcG++LR+++
   mKIAA0067   471    KNPLLVP-LLYDFRRMTARRRVN---RKMGFHVIYKTPCGLCLRTMQ 513  

                   ElarYLhkngdlslaledPLRPEYlFdFnarvpvgpkitp<-*
                   E++rYL+++g+++l+le       +F+++++v+v++k++p   
   mKIAA0067   514 EIERYLFETGCDFLFLE-------MFCLDPYVLVDRKFQP    546  

PreSET: domain 1 of 1, from 553 to 658: score 149.1, E = 4.6e-40
                   *->llDisnGkEnvPvplVeNevDedppplPpdFeYiserivgqgvvdIl
                      +lDi++GkE+vP ++V Ne+D++pp   p+  Y++eri+g+gv+   
   mKIAA0067   553    ILDITYGKEDVPLSCV-NEIDTTPP---PQVAYSKERIPGKGVF--- 592  

                   idrspsplsgCsCvdledCsssnmskCeCarknieggefaYkelrldkee
                   i+++p++l+gC+C+d  +C+++    C+C++++i+++ ++++++ +++++
   mKIAA0067   593 INTGPEFLVGCDCKD--GCRDK----CACHQLTIQATACTPGGQVNPNSG 636  

                   ekkverlngglllkakpvIYECNsrCs<-*
                        +++++l+ + ++++YECN+rC+   
   mKIAA0067   637 -----YQYKRLEECLPTGVYECNKRCN    658  

SET: domain 1 of 1, from 675 to 1143: score 153.0, E = 3.1e-41
                   *->aklevfkskgkGwGlratedIpkGefIleyvGeii............
                      ++l++fk+ +kGwG+r+++dI+kG+f++ y+G i++++  ++++ + 
   mKIAA0067   675    VRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILtddfadkeglem 721  

                   ..................................................
                   +++   + ++ ++ ++ +++ +++ ++++++++ + ++++++++++++++
   mKIAA0067   722 gdeyfanldhiesvenfkegyesdvptssdssgvdmkdqedgnsgsedpe 771  

                   ..................................................
                   ++++++++++  ++++ ++++  ++  ++++++++++++ ++ +++++++
   mKIAA0067   772 esnddssddnfckdedfstssvwrsyatrrqtrgqkenelsemtskdsrp 821  

                   ..................................................
                   ++ ++++ + +++ + ++ ++++++++++++  +  + ++ ++++  +++
   mKIAA0067   822 pdlgpphvpipssvsvggcnppsseetpknkvaswlscnsvseggfadsd 871  

                   ..................................................
                   ++++ +++++++++ ++++++ ++ ++++ + ++++++++++++++++++
   mKIAA0067   872 srssfktseggdgragggrgeaerastsglsfkdegdnkqpkkedpenrn 921  

                   ..................................................
                   + +  ++++++++++++ ++++ +++ ++ +  ++++  +++++++++  
   mKIAA0067   922 kmpvvtegsqnhghnppmkseglrrsaskmsvlqsqrvvtstqsnpddil 971  

                   ..................................................
                   + +++++++++++++++++ ++++ +  ++++ ++ ++++++++ +++++
   mKIAA0067   972 tlssstesegesgtsrkptaghtsatavdsddiqtissgsdgddfedkkn 1021 

                   .................................................f
                    +++++++   +++++   +++++   ++++  + +++++ + ++++++f
   mKIAA0067  1022 lsgptkrqvavkstrgfalksthgiaikstnmasvdkgesapvrkntrqF 1071 

                   ylfd....ciDatranggkGniarfiNHSCePNcelifvevdgfdprgas
                   y  +++   iDa+      Gn++r++NHSC+PN+ +++v+vd++d+r   
   mKIAA0067  1072 YDGEescyIIDAKL----EGNLGRYLNHSCSPNLFVQNVFVDTHDLR--- 1114 

                   dsadprivifAlrdIkpGEELtidYgddyege<-*
                      +p++++fA ++I++G+ELt+dY+++ ++    
   mKIAA0067  1115 ---FPWVAFFASKRIRAGTELTWDYNYEVGSV    1143 

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