hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbh/mbh03469/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0055  ( 1108 res)   mbh03469

Scores for sequence family classification (score includes all domains):
Model     Description                                   Score    E-value  N 
--------  -----------                                   -----    ------- ---
UCH       Ubiquitin carboxyl-terminal hydrolase         407.5   1.3e-118   1
Rhodanese Rhodanese-like domain                          60.3    4.3e-14   1
TolA      TolA protein                                 -159.3       0.86   1

Parsed for domains:
Model     Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------  ------- ----- -----    ----- -----      -----  -------
Rhodanese   1/1     212   335 ..     1   132 []    60.3  4.3e-14
TolA        1/1     394   690 ..     1   448 []  -159.3     0.86
UCH         1/1     764  1096 ..     1   273 []   407.5 1.3e-118

Alignments of top-scoring domains:
Rhodanese: domain 1 of 1, from 212 to 335: score 60.3, E = 4.3e-14
                   *->tagelkalles.apkliliDvRspefGeryeyegGHIpgAvNvplee
                      ta+el+ ++ +++ +li++D+R       + y+ ++I  +  vp ee
   mKIAA0055   212    TAKELYTMMMDkNTSLIIMDARKI-----QDYQHSCILDSLSVP-EE 252  

                   eiealldrsgilpdieklhllkdpeelaklfgelgsskdkrvivycrsgr
                   +i+  +++s+i++      l++d ++++k+ g+  +   + +  + +s +
   mKIAA0055   253 AISPGVTASWIEA-----NLSDDSKDTWKKRGSVDY---VVLLDWFSSAK 294  

                   dl.....lrnrrsalaalllkklGypeVyiLkGGykeWlak<-*
                   dl  +++lr+   al+ +++k+    e+ +L+GGy++Wl +   
   mKIAA0055   295 DLllgttLRSLKDALFKWESKTVLRHEPLVLEGGYENWLLC    335  

TolA: domain 1 of 1, from 394 to 690: score -159.3, E = 0.86
                   *->keqndklkrAiiISvvLHiiLialLilgSldetvepepgGeGggsvi
                      + q +kl                   l+     + p+  G G ++  
   mKIAA0055   394    TDQDEKLR------------------LS-----TQPALAGPGAAPRA 417  

                   dAV.mVDpgaVaqQynrlqqQkedaarkekktEPvvEEkPvePdqeRkkk
                   +A +++ p  ++  + +    k+   +                 ++  +k
   mKIAA0055   418 EASpIIQPAPATKSVPQVDRTKKPSVKLP---------------EDHRIK 452  

                   lqrqaeeleqkraaEqerlKeLekerlqaqeaakkqaEearkqaeeqqKq
                    +   +  +    +            l ++e a+  +E a     e+ Kq
   mKIAA0055   453 SENTDQSGRVLSDRSTKPVFPSPTTMLTDEEKARIHQETALL--MEKNKQ 500  

                   aEEakakqakEaakaKaeAeaaKakeeaerkakeekaaAaAakkAEeeak
                   + E+  kq kE+ k K+        ee+erka          + A e   
   mKIAA0055   501 EKELWDKQQKEQ-KEKLRR------EEQERKAGKT-------QDADERDS 536  

                   akaAAeAkkkAeaeaAelkkkakarEaaaAeAkkkaeaEAkaKaaaeAea
                    + +  Ak  +e+     ++k + rE         + a+ +  +a     
   mKIAA0055   537 TENQHKAKDGQEKKD-SKQTKTEDRE---------LSADGA-QEATGTQR 575  

                   KAkaEkAkAdaeAkaKAeaerkAdeeAAkeKAAAEAakKAaaekeraaaa
                     k E              e            A +  +K   e +r    
   mKIAA0055   576 QSKSE-------------HE------------ASD--AKVPVEGKRCPTS 598  

                   eakrKAAAEkaAaadqeaevdDifGsLssgkNapkqGggAkGagaasads
                   ea +  A    A+         + G+L  gk a++         ++    
   mKIAA0055   599 EAQKRPADVSPAS---------VSGELNAGK-AQRE-------PLTR--- 628  

                   GktkksGasGaevdqYagqiksaIqsrlldddsyaGKtCrvrikLapDGt
                             a   + + ++  +    l  +  +   t + r    p+  
   mKIAA0055   629 ----------ARSEEMGRIVPGL---PLGWAKFLDPITGTFRYYHSPTN- 664  

                   dallisvksegGDpalCqAAlaAvAktakiPkpPsddaVYeklKninldf
                     ++  + +e        A  +A         pPs++        ++ ++
   mKIAA0055   665 --TVHMYPPE-------MAPSSA---------PPSTP--------PTHKV 688  

                   kl<-*
                   k+   
   mKIAA0055   689 KP    690  

UCH: domain 1 of 1, from 764 to 1096: score 407.5, E = 1.3e-118
                RF    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   *->pgptGLvNlGNTCYmNSvLQcLfhipplrdyllsdsyeseinesnpl
                      p +tGL+NlGNTCYmNS+LQcL++ p l+dy++++ y++ in+sn l
   mKIAA0055   764    PALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLL 810  

                RF xxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   gskgsllcaladLfnalqsg.yksvvpsplkflqfkttlgkineefsgym
                   g+kg++++++  +++al++g+y++++p+ +k+     t+gkin++f+g+ 
   mKIAA0055   811 GHKGEVAEEFGIIMKALWTGqYRYISPKDFKV-----TIGKINDQFAGSS 855  

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxx xxx xxxxxxx
                   QqDAhEFllfLLdgLhedlnrvnkkpytepe.sdkrpd.kaa.eawknhs
                   QqD++E+llfL+dgLhedln++  ++++++e++++++d  aa++aw++h+
   mKIAA0055   856 QQDSQELLLFLMDGLHEDLNKADNRKRHKEEnNEHLDDlQAAeHAWQKHK 905  

                RF xxxxxxxxxxxxxxxxx                                 
                   lrneslitdlFqGqles.................................
                     nes+i+ lFqGq++s+ ++ ++++++++ +     + +  ++++++ +
   mKIAA0055   906 QLNESIIVALFQGQFKStvqcltcrrrsrtfeafmylslplastskctlq 955  

                RF                                xxxxxxxxxxxxxxxxxxx
                   ...............................rlkisrLPpiLiihLKRFk
                   ++ +  +++++ +++++  +++++ ++++ +++ i++LPp+L +hLKRF+
   mKIAA0055   956 dclrlfskeekltdnnrfycshcrarrdslkKIEIWKLPPVLLVHLKRFS 1005 

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx   xxxxxxxxxxxxxxxxx
                   ydgetgmnkKindkVefPleLdlssyctae...pplkYeLyaVvvHsGss
                   ydg+  +++K+ ++V+fPle+++ s ++ ++++   kY+L++V++H+G +
   mKIAA0055  1006 YDGR--WKQKLQTSVDFPLENLDLSQYVIGpknSLKKYNLFSVSNHYG-G 1052 

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx   
                   lsgGHYiayikkkkknnkWykfDDekVsevseeevlersssAYiLFY<-*
                   l+gGHY+ay+k ++ +++W+kfDD+ Vs++s++ v  rss+AYiLFY   
   mKIAA0055  1053 LDGGHYTAYCK-NAARQRWFKFDDHEVSDISVSSV--RSSAAYILFY    1096 

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