hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mpf/mpf00519/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0051  ( 1681 res)   mpf00519

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RasGAP   GTPase-activator protein for Ras-like GTPase   310.3    1.3e-88   1
CH       Calponin homology domain                        82.5    5.2e-20   1
IQ       Short calmodulin-binding motif containing co    80.4    2.2e-19   4

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
CH         1/1      70   179 ..     1   100 []    82.5  5.2e-20
IQ         1/4     768   790 ..     1    23 []    25.0     0.01
IQ         2/4     798   820 ..     1    23 []    30.1   0.0003
IQ         3/4     828   850 ..     1    23 []    19.9     0.35
IQ         4/4     858   880 ..     1    23 []    11.1       21
RasGAP     1/1    1016  1369 ..     1   390 []   310.3  1.3e-88

Alignments of top-scoring domains:
CH: domain 1 of 1, from 70 to 179: score 82.5, E = 5.2e-20
                   *->eeeallrWinsll.....kvtnfssdlkDGvvLckLlnslsPagsvd
                        e+++rW++++l+++ +++t+++++l++Gv L+kL n +sP + v+
   mKIAA0051    70    HLEEAKRWMEACLgedlpPTTELEEGLRNGVYLAKLGNFFSP-KVVS 115  

                   kkk..............rfkkleNinlalsfaeklgafLGvgkvvlfdpe
                    kk  ++++++ + ++ +f++++N+ ++l++++++    G++k ++ ++ 
   mKIAA0051   116 LKKiydreqtrykatglHFRHTDNVIQWLNAMDEI----GLPKIFYPETT 161  

                   DlvegnenkklilgviwtLirl<-*
                   D+++    +k+++ +i+++++l   
   mKIAA0051   162 DIYD----RKNMPRCIYCIHAL    179  

IQ: domain 1 of 4, from 768 to 790: score 25.0, E = 0.01
                   *->rleraAiiIQaawRGylaRkryk<-*
                        e  ++++Qa++RGyl+R++++   
   mKIAA0051   768    ANEGLITKLQACCRGYLVRQEFR    790  

IQ: domain 2 of 4, from 798 to 820: score 30.1, E = 0.0003
                   *->rleraAiiIQaawRGylaRkryk<-*
                      ++  a+++IQ+ wRGy++ k y+   
   mKIAA0051   798    KQIPAITCIQSQWRGYKQKKAYQ    820  

IQ: domain 3 of 4, from 828 to 850: score 19.9, E = 0.35
                   *->rleraAiiIQaawRGylaRkryk<-*
                        +  +++IQ+ +R+++aRkry+   
   mKIAA0051   828    SHKDEVVKIQSLARMHQARKRYR    850  

IQ: domain 4 of 4, from 858 to 880: score 11.1, E = 21
                   *->rleraAiiIQaawRGylaRkryk<-*
                           +i+IQa++R  +aR  yk   
   mKIAA0051   858    DHINDIIKIQAFIRANKARDDYK    880  

RasGAP: domain 1 of 1, from 1016 to 1369: score 310.3, E = 1.3e-88
                   *->lkqgelgslrlktvyttdfilpseaYeeLleLllesvdvepltasla
                      ++++++ +++++ v++t+++++s+++ee+l+L l++++   l +++ 
   mKIAA0051  1016    QMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFQTA---LQEEIK 1059 

                   saleevcsvldkdelAtkLvrlFlrrgrgkpfLraLidkEvertddpvnt
                   s +++++  ++ +++++k+v  F+r  rg++ Lr+++++ v++       
   mKIAA0051  1060 SKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKE-----IM 1104 

                   lFRgNsLatKsmevymklvGnqYLhttLkpvLkkiveekkescEvDPsKl
                   +++++++ t +++ y  +v++++ +t++ + L++ v+ ++ ++  +++K 
   mKIAA0051  1105 DDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQ-ALSHEEVKT 1153 

                   evndviSfgdpvegedletnlenLlqyverlfdaIinSsdrlPygLRdic
                                   l+++++n +++++++++aI++S+d +Pyg+R+i 
   mKIAA0051  1154 ---------------RLDNSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIA 1188 

                   kqLrqaaekrFpsatqdvrykaVssFvFLRFfcPAIlSPklFnLvde...
                   k L+ +++++Fp+a +d+ +k++++++++R+++PAI+ P++F+++d + +
   mKIAA0051  1189 KVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLsag 1238 

                   .hpdpttrRtLtLiAKvlQnLANlsesksklfgsKEpwmeplfkndflkq
                   +++  ++rR+L +iAK lQ+ A+++      f + + ++     n++l q
   mKIAA0051  1239 gQLTTDQRRNLGSIAKMLQHAASNKM-----FLGDNAHLSII--NEYLSQ 1281 

                   hkdrvkdFLdelssvdepsesL.vdkveelptkskPVstisgrelsllHs
                    ++++++F++  ++v+e  ++++vd +++l+t++kPV++is++e++++H+
   mKIAA0051  1282 SYQKFRRFFQVACDVPELQDKFnVDEYSDLVTLTKPVIYISIGEIINTHT 1331 

                   lllengdalkrkknnnrDHKAlgedpldkllfklryfrltthkltngk<-
                   lll+++da+ ++ n          dp+ +ll +l ++++++  + ++   
   mKIAA0051  1332 LLLDHQDAIAPEHN----------DPIHELLDDLGEVPTIESLIGESC   1369 

                   *
                    
   mKIAA0051     -   -    

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