hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj01557/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0031  ( 976 res)   mfj01557

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
GTP_EFTU    Elongation factor Tu GTP binding domain     212.8    5.1e-60   1
EFG_C       Elongation factor G C-terminus              122.6    7.4e-33   1
EFG_IV      Elongation factor G, domain IV               91.5    1.7e-23   1
GTP_EFTU_D2 Elongation factor Tu domain 2                49.2    9.4e-11   1
MMR_HSR1    GTPase of unknown function                  -11.4      0.073   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
MMR_HSR1      1/1     134   265 ..     1   140 []   -11.4    0.073
GTP_EFTU      1/1     131   446 ..     1   299 []   212.8  5.1e-60
GTP_EFTU_D2   1/1     493   570 ..     1    75 []    49.2  9.4e-11
EFG_IV        1/1     709   828 ..     1   124 []    91.5  1.7e-23
EFG_C         1/1     830   919 ..     1    93 []   122.6  7.4e-33

Alignments of top-scoring domains:
MMR_HSR1: domain 1 of 1, from 134 to 265: score -11.4, E = 0.073
                   *->lrvaivGrPNVGKSTLiNaLtgk................kraiVsdy
                        v + G    GK+ ++  L+ +++++ +++ +++   +++  ++  
   mKIAA0031   134    RNVTLCGHLHHGKTCFVDCLIEQthpeirkrydqdlcytDILFTEQE 180  

                   PGtTrdpnegrvel.....dgrqiilvDTPGiiegaskgegelgertlea
                    G+ +  + ++v l++++++ + + + DTPG +  ++++         + 
   mKIAA0031   181 RGVGIKSTPVTVVLpdtkgKSYLFNIMDTPGHVNFSDEVT--------AG 222  

                   ieeaDlilfVvDasegltedytieeDleiadllydeerernleltLqele
                   ++ +D +++ +Da eg+       + +++++ +                e
   mKIAA0031   223 LRISDGVVLFIDAAEGVM-----LNTERLIKHA----V----------QE 253  

                   kkgkPvilvlNKiD<-*
                   +++  v +++NKiD   
   mKIAA0031   254 RLA--VTVCINKID    265  

GTP_EFTU: domain 1 of 1, from 131 to 446: score 212.8, E = 5.1e-60
                   *->krhrNigiiGHVDHGKTTLtdrLlyytgaisertleklegeakegge
                      + +rN++ +GH +HGKT  +d+L+++t+   +       +  ++   
   mKIAA0031   131    ELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRK------RYDQDL-- 169  

                   rkgsfklaaviDkmeeErERGITIksahvsfewkdededletkakegkkr
                           +++D +  E+ERG+ Iks+ v+    d++             
   mKIAA0031   170 --------CYTDILFTEQERGVGIKSTPVTVVLPDTK------------- 198  

                   gnelTekrhiniIDTPGHvDFtkevirGlaqaDGAiLVVdAveGvmpGfk
                       ++++++ni DTPGHv F+ ev++Gl+  DG++L +dA+eGvm    
   mKIAA0031   199 ----GKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVML--- 241  

                   GQTrehlrlArqlgvppiilvVaiNKiDrvgaelklppvpeelyeeleke
                     T++++++A q+++  + ++  iNKiDr++ elkl   p ++y +l+++
   mKIAA0031   242 -NTERLIKHAVQERL-AVTVC--INKIDRLILELKL--PPTDAYYKLRHI 285  

                   vrellkpIg.e.df.gvidli.............................
                   v e++ +I+ +++++  i  +  ++   ++++ +   + ++  +   ++ 
   mKIAA0031   286 VDEVNGLISmYsTDeNLILSPllgnvcfsssqysicftlgsfakiyadtf 335  

                   ...............................lae.vae.ddelmeyyleg
                   ++ + ++  ++  ++   ++++++ +++ ++ + ++++  ++l+++y++ 
   mKIAA0031   336 gdinyqefakrlwgdiyfnpktrkftkkapsSSSqRSFvEFILEPLYKIL 385  

                   eeipiipiSalggdnidelsiknkLk.kd.dlslvPwykgvSalknkgrd
                    +++ +     +  ++del+i+  L++++ +l++ P++  v+ ++++   
   mKIAA0031   386 AQVVGDVD-TSLPRTLDELGIH--LTkEElKLNIRPLLRLVCKKFFG--- 429  

                   rgaiptLLealddylPsPe<-*
                         ++++ ++++PsP+   
   mKIAA0031   430 -E-FTGFVDMCVQHIPSPK    446  

GTP_EFTU_D2: domain 1 of 1, from 493 to 570: score 49.2, E = 9.4e-11
                   *->GtVatgRvesGtlkkGdeveigg.ngt.kky.vpevtrVtslemfhg
                       + a+gRv sGt++ G+ v ++g+n+t +++++ ++++V++l++  +
   mKIAA0031   493    QFHAFGRVLSGTIHAGQPVKVLGeNYTlEDEeDSQICTVGRLWISVA 539  

                   .ldeavaGdnaGlivagiglkdaaikrGdvla<-*
                   +  ++v  ++aG+ v + g+++  i +  +++   
   mKIAA0031   540 rYHIEVNRVPAGNWVLIEGVDQP-IVKTATIT    570  

EFG_IV: domain 1 of 1, from 709 to 828: score 91.5, E = 1.7e-23
                   *->pqVayrETIrkdvkereykhkkQsGgdgqyakviiriePlpgggneF
                       q+        ++k   ++++ ++++d   a+ i++++P+ +g+n+ 
   mKIAA0031   709    VQITWN-----RKK-LGEFFQTKYDWDLLAARSIWAFGPDATGPNIL 749  

                   vdetkG..vGgqiPkEyipavekGfreamkeGpLaGepvvdvkvtLvDGs
                   vd+t  ++v  +++ ++++++++Gf++ ++eGpL++e +++vk++++D++
   mKIAA0031   750 VDDTLPseVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAV 799  

                   yHeDAVdSseaaFkpAarrAfkeAllkAk<-*
                       + ++++++++p+arr+++ A+l A    
   mKIAA0031   800 VAQEPLHRGGGQIIPTARRVVYSAFLMAT    828  

EFG_C: domain 1 of 1, from 830 to 919: score 122.6, E = 7.4e-33
                   *->vlLEPimkveIivPeeylGaViglLnkRRGqildmeyrgggaPlrvr
                      +l+EP++ ve+++P + ++aV+++L +RRG+++   +++g  Pl++ 
   mKIAA0031   830    RLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGS-PLYT- 874  

                   ikaevPlaEmfGDFatdLrSlTqGrAsfsmeFdhYepvpgviadel<-*
                   ika +P+  +fG F tdLr++TqG+A+   +F+h++ vpg+ +d+    
   mKIAA0031   875 IKAFIPAIDSFG-FETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKS    919  

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