hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/msj/msj04008/w3open/interpro/cnk_1/seq.in
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Query:  mKIAA0012  ( 727 res)   msj04008

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
TIR      Toll - interleukin 1 - resistance              151.8      7e-41   1
LRR_TYP  Leucine-rich repeats, typical (most populate    56.9    2.6e-12   6
LRRCT    Leucine rich repeat C-terminal domain           52.2    6.7e-11   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
LRR_TYP    1/6       3    26 ..     1    24 []    14.7      6.7
LRR_TYP    2/6      48    72 ..     1    24 []     0.3  3.8e+02
LRR_TYP    3/6     306   329 ..     1    24 []    12.8       11
LRR_TYP    4/6     332   355 ..     1    24 []     7.0       57
LRR_TYP    5/6     380   401 ..     1    24 []     6.2       73
LRR_TYP    6/6     402   426 ..     1    24 []    15.5      5.3
LRRCT      1/1     459   513 ..     1    55 []    52.2  6.7e-11
TIR        1/1     571   714 ..     1   147 []   151.8    7e-41

Alignments of top-scoring domains:
LRR_TYP: domain 1 of 6, from 3 to 26: score 14.7, E = 6.7
                   *->LpnLreLdLsnNqLtsLPpgaFqg<-*
                      L++Lr+L  s+N+L+ L   +F     
   mKIAA0012     3    LSKLRVLIMSYNRLQYLNISVFKF    26   

LRR_TYP: domain 2 of 6, from 48 to 72: score 0.3, E = 3.8e+02
                   *->LpnLreLdLsnNqLtsLP..pgaFqg<-*
                       ++L++LdLs+N++ +LP   + F++   
   mKIAA0012    48    TVSLKHLDLSFNAFDALPicKE-FGN    72   

LRR_TYP: domain 3 of 6, from 306 to 329: score 12.8, E = 11
                   *->LpnLreLdLsnNqLtsLPpgaFqg<-*
                      L+ L++L+L+ NqL+ L + ++ +   
   mKIAA0012   306    LVRLKTLSLQKNQLKNLENIILTS    329  

LRR_TYP: domain 4 of 6, from 332 to 355: score 7.0, E = 57
                   *->LpnLreLdLsnNqLtsLPpgaFqg<-*
                      +++L++Ld s N L+    g+      
   mKIAA0012   332    MTSLQKLDISQNSLRYSDGGIPCA    355  

LRR_TYP: domain 5 of 6, from 380 to 401: score 6.2, E = 73
                   *->LpnLreLdLsnNqLtsLPpgaFqg<-*
                       p+ ++LdL+nN++ s+P ++  +   
   mKIAA0012   380    -PKVKVLDLHNNRIMSIPKDV-TH    401  

LRR_TYP: domain 6 of 6, from 402 to 426: score 15.5, E = 5.3
                   *->LpnLreLdLsnNqLtsLP.pgaFqg<-*
                      L +L+eL+  +N Lt LP+ gaF++   
   mKIAA0012   402    LQALQELNVASNSLTDLPgCGAFSS    426  

LRRCT: domain 1 of 1, from 459 to 513: score 52.2, E = 6.7e-11
                   *->NPfnCDCeLrwLlrwleaqnnealqdpvsslrCasPeslrGqpllll
                      NPf C+CeLr+++ ++  + +e+++++ +s+rC++Pes rG+ l+++
   mKIAA0012   459    NPFQCTCELRDFVKNIGWVAREVVEGWPDSYRCDYPESSRGTALRDF 505  

                   lpsefsCp<-*
                   ++s  sC+   
   mKIAA0012   506 HMSPLSCD    513  

TIR: domain 1 of 1, from 571 to 714: score 151.8, E = 7e-41
                   *->eydvFiSfrg.deedvrnefvshLlkalrgkgklcvFiDdfepgggd
                      ++ +F+S++g+d+++v ne+++ L+k+     ++c+++++f+pg+++
   mKIAA0012   571    QFHAFVSYSGhDSAWVKNELLPNLEKDDI---QICLHERNFVPGKSI 614  

                   aenkllpelfeaIekSriaivvlSpnYaeSeWCldlElvaalecale.gg
                   +en     ++  IekS ++i+vlSp++++SeWC   El +a+++ +++g+
   mKIAA0012   615 VEN-----IINFIEKSYKSIFVLSPHFIQSEWCHY-ELYFAHHNLFHeGS 658  

                   lrvIPIfyevi..sdvrkqtgkfgkvfkkngpedtylkwted......fW
                   +++I+I + +i+++ ++    k+++++ ++    tyl+w+ ++++++ fW
   mKIAA0012   659 DNLILILLAPIpqYSIPTNYHKLKTLMSRR----TYLEWPTEknkhglFW 704  

                   kkalysvpnk<-*
                    ++++s+ +k   
   mKIAA0012   705 ANLRASINVK    714  

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